Search Results - "Sandoval, Nichole"

Discovery of novel N-acylpyrazoles as potent and selective thrombin inhibitors by Short, Kevin M., Estiarte, M. Angels, Pham, Son M., Williams, David C., Igoudin, Lev, Dash, Subhadra, Sandoval, Nichole, Datta, Anirban, Pozzi, Nicola, Di Cera, Enrico, Kita, David B.

“…Direct oral anticoagulants (DOACs), which includes thrombin and factor Xa inhibitors, have emerged as the preferred therapeutics for thrombotic disorders,…”
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Novel Class of Direct Thrombin Inhibitors Prevent Thrombosis By Inhibiting Fibrinogen Cleavage While Preserving Platelet Function by Sivaraja, Mohan, Sizikov, Sivan, Sandoval, Nichole, Lin, Kenneth, Igoudin, Lev, Dash, Subhadra, Xu, Chengpei, Clemens, Daniel, Estiarte, Angels, Shiau, Timothy, Short, Kevin, Williams, David, Datta, Anirban, Kita, David

“…We have developed a new class of direct thrombin inhibitors (VE-DTIs) that act through reversible covalent enzyme inhibition. These compounds inhibit thrombin…”
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Abstract 15865: Novel, Highly Selective Direct Thrombin Inhibitors: Efficacy, Safety, and Tolerability Studies by Xu, Chengpei, Dash, Subhadra, Clemens, Daniel, Lin, Kenneth, Neckermann, Georg, Yau, Simon, To, Elaine, Igoudin, Lev, Keutzer, Samuel, Sandoval, Nichole, Sizikov, Sivan, Estiarte, Angels, Short, Kevin, Shiau, Timothy, Williams, David, Sivaraja, Mohan, Datta, Anirban, Kita, David

“…Patients with atrial fibrillation and venous thromboembolism require anticoagulation prophylaxis/treatment. Direct oral anticoagulants (DOACs) offer certain…”
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