Search Results - "Sandoval, Cristian"

Role of copper nanoparticles in wound healing for chronic wounds: literature review by Salvo, Jessica, Sandoval, Cristian

“…Abstract Chronic wounds are defined as wounds that fail to proceed through the normal phases of wound healing in an orderly and timely manner. The most common…”
Get full text

Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy by Sandoval-Acuña, Cristian, Torrealba, Natalia, Tomkova, Veronika, Jadhav, Sukanya B, Blazkova, Kristyna, Merta, Ladislav, Lettlova, Sandra, Adamcová, Miroslava K, Rosel, Daniel, Brábek, Jan, Neuzil, Jiri, Stursa, Jan, Werner, Lukas, Truksa, Jaroslav

“…Deferoxamine (DFO) represents a widely used iron chelator for the treatment of iron overload. Here we describe the use of mitochondrially targeted deferoxamine…”
Get full text

First Web-Based Database on Total Phenolics and Oxygen Radical Absorbance Capacity (ORAC) of Fruits Produced and Consumed within the South Andes Region of South America by Speisky, Hernan, López-Alarcón, Camilo, Gómez, Maritza, Fuentes, Jocelyn, Sandoval-Acuña, Cristian

“…This paper reports the first database on antioxidants contained in fruits produced and consumed within the south Andes region of South America. The database…”
Get full text

An Updated Overview of the Role of CYP450 during Xenobiotic Metabolization in Regulating the Acute Myeloid Leukemia Microenvironment by Sandoval, Cristian, Calle, Yolanda, Godoy, Karina, Farías, Jorge

“…Oxidative stress is associated with several acute and chronic disorders, including hematological malignancies such as acute myeloid leukemia, the most…”
Get full text

Editorial: Advances in novel pharmacotherapeutics and drug discovery: computational, experimental, translational, and clinical models by Sandoval, Cristian, Torrens, Francisco, Souza-Mello, Vanessa, Farías, Jorge

Get full text

Effectiveness of mRNA, protein subunit vaccine and viral vectors vaccines against SARS-CoV-2 in people over 18 years old: a systematic review by Sandoval, Cristian, Guerrero, Daniela, Muñoz, Joham, Godoy, Karina, Souza-Mello, Vanessa, Farías, Jorge

“…Vaccines prevent disease and disability; save lives and represent a good assessment of health interventions. Several systematic reviews on the efficacy and…”
Get full text

Aesthetic Rib Cage Remodeling with Osteosynthesis: Body Structural High-Definition Reshaping (RIBOSS) by Aguilar Villa, Hugo, Villabona-Florez, Silvia J, Hoyos, Alfredo E, Perez Pachon, Mauricio E, Serrano-Reyes, Hector Mauricio, Diaz Sandoval, Cristian J

“…Rib cage remodeling has shown promising aesthetic results as a new technique for body contouring yet risks and complications associated with the procedure have…”
Get full text

Effectiveness of Cerium Oxide Nanoparticles in Non-Alcoholic Fatty Liver Disease Evolution Using In Vivo and In Vitro Studies: A Systematic Review by Sandoval, Cristian, Reyes, Carolina, Rosas, Pamela, Godoy, Karina, Souza-Mello, Vanessa, Farías, Jorge

“…Nonalcoholic fatty liver disease (NAFLD) describes a spectrum of liver abnormalities, from benign steatosis to nonalcoholic steatohepatitis (NASH). Because of…”
Get full text

Application of Quantitative Structure-Activity Relationships in the Prediction of New Compounds with Anti-Leukemic Activity by Sandoval, Cristian, Torrens, Francisco, Godoy, Karina, Reyes, Camila, Farías, Jorge

“…Leukemia invades the bone marrow progressively and, through unknown mechanisms, outcompetes healthy hematopoiesis. Protein arginine methyltransferases 1…”
Get full text

β-Carotene Supplementation Improves Pancreas Function during Moderate Ethanol Consumption: Initial Characterization from a Morphological Overview by Sandoval, Cristian, Vera, Angeles, Birditt, Katherine, Godoy, Karina, Carmine, Florencia, Caamaño, José, Farías, Jorge

“…Alcohol is believed to harm acinar cells, pancreatic ductal epithelium, and pancreatic stellate cells. After giving ethanol and/or β-carotene to mice, our goal…”
Get full text

Effectiveness of Copper Nanoparticles in Wound Healing Process Using In Vivo and In Vitro Studies: A Systematic Review by Sandoval, Cristian, Ríos, Gemima, Sepúlveda, Natalia, Salvo, Jessica, Souza-Mello, Vanessa, Farías, Jorge

“…Chronic wounds are defined as wounds that do not heal in an orderly and timely manner through the various stages of the healing process. Copper nanoparticles…”
Get full text

Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene by Novakova, Zora, Milosevic, Mirko, Kutil, Zsofia, Ondrakova, Marketa, Havlinova, Barbora, Kasparek, Petr, Sandoval-Acuña, Cristian, Korandova, Zuzana, Truksa, Jaroslav, Vrbacky, Marek, Rohlena, Jakub, Barinka, Cyril

“…In humans, disruptions in the heme biosynthetic pathway are associated with various types of porphyrias, including variegate porphyria that results from the…”
Get full text

NDRG1 acts as an oncogene in triple-negative breast cancer and its loss sensitizes cells to mitochondrial iron chelation by Jadhav, Sukanya B, Vondrackova, Michaela, Potomova, Petra, Sandoval-Acuña, Cristian, Smigova, Jana, Klanicova, Kristyna, Rosel, Daniel, Brabek, Jan, Stursa, Jan, Werner, Lukas, Truksa, Jaroslav

“…Multiple studies indicate that iron chelators enhance their anti-cancer properties by inducing NDRG1, a known tumor and metastasis suppressor. However, the…”
Get full text

Healing Effect of a Nano-Functionalized Medical-Grade Honey for the Treatment of Infected Wounds by Salvo, Jessica, Sandoval, Cristian, Schencke, Carolina, Acevedo, Francisca, del Sol, Mariano

“…Based on the qualities of Ulmo honey (Eucryphia cordifolia), a medical-grade honey (Ulmoplus®) has been developed. Relevant to this, the use of copper…”
Get full text

Vitamin Supplements as a Nutritional Strategy against Chronic Alcohol Consumption? An Updated Review by Sandoval, Cristian, Farías, Jorge, Zamorano, Mauricio, Herrera, Christian

“…Several studies have shown that blood vitamin levels are low in alcoholic patients. In effect, alcohol use abuse is considered a chronic disease that promotes…”
Get full text

Effectiveness of antioxidant treatments on cytochrome P450 2E1 (CYP2E1) activity after alcohol exposure in humans and in vitro models: A systematic review by Carrasco, Danitza, Carrasco, Camila, Souza-Mello, Vanessa, Sandoval, Cristian

“…This systematic review aimed to describe the effects of antioxidant treatments after alcohol exposure in humans and in vitro models. A systematic review of…”
Get full text

β-Carotene Increases Activity of Cytochrome P450 2E1 during Ethanol Consumption by Sandoval, Cristian, Mella, Luciana, Godoy, Karina, Adeli, Khosrow, Farías, Jorge

“…One of the key routes through which ethanol induces oxidative stress appears to be the activation of cytochrome P450 2E1 at different levels of ethanol intake…”
Get full text

Effect of hypoxia on the post-hatching growth of the body of the fry and the caudal fin of the Atlantic Salmon (Salmo salar) by Rojas, Mariana, Salvatierra, Renato, Smok, Carolina, Sandoval, Cristian, Souza-Mello, Vanessa, del Sol, Mariano

“…IntroductionHypoxia is a recurring problem in the fish farming industry. Currently, it is known that the exposure of fish and fry to a hypoxic environment…”
Get full text

Genotype analysis to clarify RhD variants in discrepant samples of Chilean population by Aburto, Andrés, Zapata, Diego, Retamales, Eduardo, Fernández, Jorge, Barra, Gisselle, Peña, Francisca, Cárcamo, Sofía, Saavedra, Nicolás, Sandoval, Cristian, Orellana, Juan, Caamaño, José

“…The D antigen variants are classified as weak, partial, and extremely weak (DEL) and can be differentiated using molecular tests. In Chile, the laboratories of…”
Get full text

Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model by Seborova, Karolina, Koucka, Kamila, Spalenkova, Alzbeta, Holy, Petr, Ehrlichova, Marie, Sychra, Tomas, Chen, Lei, Bendale, Hersh, Ojima, Iwao, Sandoval-Acuña, Cristian, Truksa, Jaroslav, Soucek, Pavel, Vaclavikova, Radka

“…Taxanes are widely used in the treatment of ovarian carcinomas. One of the main problems with conventional taxanes is the risk of development of multidrug…”
Get full text