Search Results - "Sandmann, Axel"

Evolutionary implications of bacterial polyketide synthases by Jenke-Kodama, Holger, Sandmann, Axel, Müller, Rolf, Dittmann, Elke

“…Polyketide synthases (PKS) perform a stepwise biosynthesis of diverse carbon skeletons from simple activated carboxylic acid units. The products of the complex…”
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Completing the puzzle of aurachin biosynthesis in Stigmatella aurantiaca Sg a15 by Pistorius, Dominik, Li, Yanyan, Sandmann, Axel, Müller, Rolf

“…The aurachins are a family of secondary metabolites, with the main members aurachin A, B, C, and D, produced by the myxobacterium Stigmatella aurantiaca Sg…”
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A Type II Polyketide Synthase from the Gram-Negative Bacterium Stigmatella aurantiaca Is Involved in Aurachin Alkaloid Biosynthesis by Sandmann, Axel, Dickschat, Jeroen, Jenke-Kodama, Holger, Kunze, Brigitte, Dittmann, Elke, Müller, Rolf

“…A closer look: The path for the biosynthesis of aurachin alkaloids (aurachin A is shown) has been deduced by molecular biological methods, including the…”
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Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase by Petković, Hrvoje, Sandmann, Axel, Challis, Iain R, Hecht, Hans-Jürgen, Silakowski, Barbara, Low, Lindsey, Beeston, Nicola, Kuscer, Enej, Garcia-Bernardo, Jose, Leadlay, Peter F, Kendrew, Steven G, Wilkinson, Barrie, Müller, Rolf

“…The production of epothilone mixtures is a direct consequence of the substrate tolerance of the module 3 acyltransferase (AT) domain of the epothilone…”
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DKxanthene Biosynthesis—Understanding the Basis for Diversity-Oriented Synthesis in Myxobacterial Secondary Metabolism by Meiser, Peter, Weissman, Kira J., Bode, Helge B., Krug, Daniel, Dickschat, Jeroen S., Sandmann, Axel, Müller, Rolf

“…The DKxanthenes are a family of yellow pigments which play a critical role in myxobacterial development. Thirteen unique structures from Myxococcus xanthus…”
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Critical variations of conjugational DNA transfer into secondary metabolite multiproducing Sorangium cellulosum strains So ce12 and So ce56: development of a mariner-based transposon mutagenesis system by Kopp, Maren, Irschik, Herbert, Gross, Frank, Perlova, Olena, Sandmann, Axel, Gerth, Klaus, Müller, Rolf

“…Myxobacteria increasingly gain attention as a source of bioactive natural products. The genus Sorangium produces almost half of the secondary metabolites…”
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A TypeII Polyketide Synthase from the Gram-Negative Bacterium Stigmatella aurantiaca Is Involved in Aurachin Alkaloid Biosynthesis by Sandmann, Axel, Dickschat, Jeroen, Jenke-Kodama, Holger, Kunze, Brigitte, Dittmann, Elke, Muller, Rolf

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Aurachin‐Biosynthese im Gram‐negativen Bakterium Stigmatella aurantiaca: Beteiligung einer Typ‐II‐Polyketidsynthase by Sandmann, Axel, Dickschat, Jeroen, Jenke‐Kodama, Holger, Kunze, Brigitte, Dittmann, Elke, Müller, Rolf

“…Unter der Lupe: Der Biosyntheseweg zur Bildung der Aurachin‐Alkaloide (gezeigt ist Aurachin A) wurde mithilfe molekularbiologischer Methoden, einschließlich…”
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Identification and Analysis of the Core Biosynthetic Machinery of Tubulysin, a Potent Cytotoxin with Potential Anticancer Activity by Sandmann, Axel, Sasse, Florenz, Müller, Rolf

“…Myxobacteria are well known for their biosynthetic potential, especially for the production of cytotoxic compounds with potential anticancer activities. The…”
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Aurachin-Biosynthese im Gram-negativen Bakterium Stigmatella aurantiaca: Beteiligung einer Typ-II-Polyketidsynthase by Sandmann, Axel, Dickschat, Jeroen, Jenke-Kodama, Holger, Kunze, Brigitte, Dittmann, Elke, Müller, Rolf

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