Correlation of postmortem MRI and CT appearances with neuropathology in brain trauma: a comparison of two methods

Correlation of postmortem MRI and CT appearances with neuropathology in brain trauma: a comparison of two methods

Postmortem magnetic resonance (MR) scans were performed on the brains of 12 victims of fatal head injuries. These were compared with neuropathological studies of the entire brain. The first six subjects were imaged with the brain in situ and comparison was also made with antemortem computed tomograp...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical neuroscience Vol. 5; no. 1; pp. 73 - 79
Main Authors: Jones, Nigel R, Blumbergs, Peter C, Brown, Christopher J, McLean, A.Jack, Manavis, James, Perrett, Lance V, Sandhu, Avinder, Scott, Grace, Simpson, Donald A
Format: Journal Article
Language:English
Published: Amsterdam Elsevier Ltd 1998
Elsevier
Subjects:
axonal injury
Biological and medical sciences
head injury
Injuries of the nervous system and the skull. Diseases due to physical agents
Medical sciences
MRI
neuropathology
Traumas. Diseases due to physical agents
CT
axonal injury
MRI
head injury
neuropathology
Human
Nervous system diseases
Correlation
Radiodiagnosis
Craniocerebral
Diseases of the osteoarticular system
Postmortem
Exploration
Nuclear magnetic resonance imaging
Trauma
Cerebral disorder
Pathology
Central nervous system disease
Skull disease
Medical imagery
Computerized axial tomography
Comparative study
Brain (vertebrata)
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Postmortem magnetic resonance (MR) scans were performed on the brains of 12 victims of fatal head injuries. These were compared with neuropathological studies of the entire brain. The first six subjects were imaged with the brain in situ and comparison was also made with antemortem computed tomography (CT). The brains from the subsequent six subjects were removed at autopsy, fixed in formalin and then imaged in a mitre box designed to overcome the problems encountered in the pilot study. Although both CT and MR imaging (MRI) detected all clinically relevant haemorrhagic lesions, many pathologically significant lesions were missed. MRI detected many more lesions than CT, but still failed to visualize areas of non-haemorrhagic axonal injury.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0967-5868
1532-2653
DOI:10.1016/S0967-5868(98)90207-7