Search Results - "Sandfort, Veit"
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Data augmentation using generative adversarial networks (CycleGAN) to improve generalizability in CT segmentation tasks
Published in Scientific reports (15-11-2019)“…Labeled medical imaging data is scarce and expensive to generate. To achieve generalizable deep learning models large amounts of data are needed. Standard data…”
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Automated Liver Fat Quantification at Nonenhanced Abdominal CT for Population-based Steatosis Assessment
Published in Radiology (01-11-2019)“…Background Nonalcoholic fatty liver disease and its consequences are a growing public health concern requiring cross-sectional imaging for noninvasive…”
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Risk score overestimation: the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort
Published in European heart journal (21-02-2017)“…To evaluate the 2013 American Heart Association (AHA)-American College of Cardiology (ACC)-Atherosclerotic Cardiovascular Disease (ASCVD) risk score among four…”
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Automated CT biomarkers for opportunistic prediction of future cardiovascular events and mortality in an asymptomatic screening population: a retrospective cohort study
Published in The Lancet. Digital health (01-04-2020)“…Body CT scans are frequently done for a wide range of clinical indications, but potentially valuable biometric information typically goes unused. We aimed to…”
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Fully automated CT imaging biomarkers of bone, muscle, and fat: correcting for the effect of intravenous contrast
Published in Abdominal radiology (New York) (01-03-2021)“…Purpose Fully automated CT-based algorithms for quantifying bone, muscle, and fat have been validated for unenhanced abdominal scans. The purpose of this study…”
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Spectral photon-counting CT in cardiovascular imaging
Published in Journal of cardiovascular computed tomography (01-05-2021)“…Photon-counting computed tomography (PCCT) is an emerging technology promising to substantially improve cardiovascular imaging. Recent engineering and…”
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3D matrix-based cell cultures: Automated analysis of tumor cell survival and proliferation
Published in International journal of oncology (01-01-2016)“…Three-dimensional ex vivo cell cultures mimic physiological in vivo growth conditions thereby significantly contributing to our understanding of tumor cell…”
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Reliable segmentation of 2D cardiac magnetic resonance perfusion image sequences using time as the 3rd dimension
Published in European radiology (01-06-2021)“…Objectives Cardiac magnetic resonance (CMR) first-pass perfusion is an established noninvasive diagnostic imaging modality for detecting myocardial ischemia. A…”
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Coronary Artery Calcium to Guide a Personalized Risk-Based Approach to Initiation and Intensification of Antihypertensive Therapy
Published in Circulation (New York, N.Y.) (10-01-2017)“…BACKGROUND:The use of atherosclerotic cardiovascular disease (ASCVD) risk to personalize systolic blood pressure (SBP) treatment goals is a topic of increasing…”
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Coronary CT Angiography: Variability of CT Scanners and Readers in Measurement of Plaque Volume
Published in Radiology (01-12-2016)“…Purpose To determine reader and computed tomography (CT) scan variability for measurement of coronary plaque volume. Materials and Methods This HIPAA-compliant…”
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Dual-contrast agent photon-counting computed tomography of the heart: initial experience
Published in The International Journal of Cardiovascular Imaging (01-08-2017)“…To determine the feasibility of dual—contrast agent imaging of the heart using photon-counting detector (PCD) computed tomography (CT) to simultaneously assess…”
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Long-term expression changes of immune-related genes in prostate cancer after radiotherapy
Published in Cancer Immunology, Immunotherapy (01-04-2022)“…The expression of immune-related genes in cancer cells can alter the anti-tumor immune response and thereby impact patient outcomes. Radiotherapy has been…”
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Automated assessment of longitudinal biomarker changes at abdominal CT: correlation with subsequent cardiovascular events in an asymptomatic adult screening cohort
Published in Abdominal radiology (New York) (01-06-2021)“…Background Cardiovascular (CV) disease is a major public health concern, and automated methods can potentially capture relevant longitudinal changes on CT for…”
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Exploiting Radiation-Induced Signaling to Increase the Susceptibility of Resistant Cancer Cells to Targeted Drugs: AKT and mTOR Inhibitors as an Example
Published in Molecular cancer therapeutics (01-02-2018)“…Implementing targeted drug therapy in radio-oncologic treatment regimens has greatly improved the outcome of cancer patients. However, the efficacy of…”
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The lncRNAs LINC00261 and LINC00665 are upregulated in long-term prostate cancer adaptation after radiotherapy
Published in Molecular therapy. Nucleic acids (04-06-2021)“…Long non-coding RNAs (lncRNAs) have been shown to impact important biological functions such as proliferation, survival, and genomic stability. To analyze…”
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Coronary calcium density in relation to coronary heart disease and cardiovascular disease in adults with diabetes or metabolic syndrome: the Multi-ethnic Study of Atherosclerosis (MESA)
Published in BMC cardiovascular disorders (09-12-2022)“…Coronary artery calcium (CAC) density is inversely associated with coronary heart disease (CHD) and cardiovascular disease (CVD) risk. We examined this…”
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Cardiac cine CT approaching 1 mSv: implementation and assessment of a 58-ms temporal resolution protocol
Published in The International Journal of Cardiovascular Imaging (01-08-2020)“…Clinical use of cardiac cine CT imaging is limited by high radiation dose and low temporal resolution. To evaluate a low radiation dose, high temporal…”
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Impact of Replacing the Pooled Cohort Equation with Other Cardiovascular Disease Risk Scores on Atherosclerotic Cardiovascular Disease Risk Assessment (from the MultiEthnic Study of Atherosclerosis [MESA])
Published in The American journal of cardiology (01-09-2016)“…Abstract The increase in statin eligibility by the new cholesterol guidelines is mostly driven by the Pooled Cohort Equation (PCE) criterion (≥ 7.5% 10yr…”
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The role of the focal adhesion protein PINCH1 for the radiosensitivity of adhesion and suspension cell cultures
Published in PloS one (28-09-2010)“…Focal adhesion (FA) signaling mediated by adhesion to extracellular matrix and growth factor receptors contributes to the regulation of the cellular stress…”
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Importance of the lipid‐related pathways in the association between statins, mortality, and cardiovascular disease risk: The Multi‐Ethnic Study of Atherosclerosis
Published in Pharmacoepidemiology and drug safety (01-04-2018)“…Purpose Estimating how much of the impact of statins on coronary heart diseases (CHD), cardiovascular disease (CVD), and mortality risk is attributable to…”
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