Search Results - "Sanders, Philip"

Exceptional Response to Nivolumab and Stereotactic Body Radiation Therapy (SBRT) in Neuroendocrine Cervical Carcinoma with High Tumor Mutational Burden: Management Considerations from the Center For Personalized Cancer Therapy at UC San Diego Moores Cancer Center by Sharabi, Andrew, Kim, Sangwoo Shawn, Kato, Shumei, Sanders, Philip D., Patel, Sandip Pravin, Sanghvi, Parag, Weihe, Elizabeth, Kurzrock, Razelle

“…Neuroendocrine carcinoma of the cervix is an ultra‐rare malignancy with a poor prognosis and limited treatment options. Checkpoint blockade immunotherapy has…”
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Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage by Scott, Ian C., Majithiya, Jayesh B., Sanden, Caroline, Thornton, Peter, Sanders, Philip N., Moore, Tom, Guscott, Molly, Corkill, Dominic J., Erjefält, Jonas S., Cohen, E. Suzanne

“…Interleukin (IL)-33 is an IL-1 family alarmin released from damaged epithelial and endothelial barriers to elicit immune responses and allergic inflammation…”
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A randomized single-blind controlled trial of a prototype digital polytherapeutic for tinnitus by Searchfield, Grant D., Sanders, Philip J.

“…Objective This randomized single-blind controlled trial tested the hypothesis that a prototype digital therapeutic developed to provide goal-based counseling…”
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A review of plasticity induced by auditory and visual tetanic stimulation in humans by Sanders, Philip J., Thompson, Benjamin, Corballis, Paul M., Maslin, Michael, Searchfield, Grant D.

“…Long‐term potentiation is a form of synaptic plasticity thought to play an important role in learning and memory. Recently noninvasive methods have been…”
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Prediction of Tinnitus Treatment Outcomes Based on EEG Sensors and TFI Score Using Deep Learning by Doborjeh, Maryam, Liu, Xiaoxu, Doborjeh, Zohreh, Shen, Yuanyuan, Searchfield, Grant, Sanders, Philip, Wang, Grace Y, Sumich, Alexander, Yan, Wei Qi

“…Tinnitus is a hearing disorder that is characterized by the perception of sounds in the absence of an external source. Currently, there is no pharmaceutical…”
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Mitochondrial-targeted antioxidant therapy decreases transforming growth factor-β-mediated collagen production in a murine asthma model by Jaffer, Omar A, Carter, A Brent, Sanders, Philip N, Dibbern, Megan E, Winters, Christopher J, Murthy, Shubha, Ryan, Alan J, Rokita, Adam G, Prasad, Anand M, Zabner, Joseph, Kline, Joel N, Grumbach, Isabella M, Anderson, Mark E

“…Asthma is a disease of acute and chronic inflammation in which cytokines play a critical role in orchestrating the allergic inflammatory response. IL-13 and…”
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A State-of-Art Review of Digital Technologies for the Next Generation of Tinnitus Therapeutics by Searchfield, Grant D, Sanders, Philip J, Doborjeh, Zohreh, Doborjeh, Maryam, Boldu, Roger, Sun, Kevin, Barde, Amit

“…Digital processing has enabled the development of several generations of technology for tinnitus therapy. The first digital generation was comprised of digital…”
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Sildenafil Prevents and Reverses Transverse-Tubule Remodeling and Ca2+ Handling Dysfunction in Right Ventricle Failure Induced by Pulmonary Artery Hypertension by Xie, Yu-Ping, Chen, Biyi, Sanders, Philip, Guo, Ang, Li, Yue, Zimmerman, Kathy, Wang, Lie-Cheng, Weiss, Robert M, Grumbach, Isabella M, Anderson, Mark E, Song, Long-Sheng

“…Right ventricular (RV) failure (RVF) is the main cause of death in patients with pulmonary artery hypertension (PAH). Sildenafil, a phosphodiesterase type 5…”
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Lysophosphatidylcholine Acyltransferase 3 Knockdown-mediated Liver Lysophosphatidylcholine Accumulation Promotes Very Low Density Lipoprotein Production by Enhancing Microsomal Triglyceride Transfer Protein Expression by Li, Zhiqiang, Ding, Tingbo, Pan, Xiaoyue, Li, Yan, Li, Ruohan, Sanders, Philip E., Kuo, Ming-Shang, Hussain, M. Mahmood, Cao, Guoqing, Jiang, Xian-Cheng

“…After de novo biosynthesis phospholipids undergo extensive remodeling by the Lands' cycle. Enzymes involved in phospholipid biosynthesis have been studied…”
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AGPAT6 Is a Novel Microsomal Glycerol-3-phosphate Acyltransferase by Chen, Yan Qun, Kuo, Ming-Shang, Li, Shuyu, Bui, Hai H., Peake, David A., Sanders, Philip E., Thibodeaux, Stefan J., Chu, Shaoyou, Qian, Yue-Wei, Zhao, Yang, Bredt, David S., Moller, David E., Konrad, Robert J., Beigneux, Anne P., Young, Stephen G., Cao, Guoqing

“…AGPAT6 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase (AGPAT) family that appears to be important in triglyceride biosynthesis in several…”
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The Multifunctional Ca2+/Calmodulin-dependent Kinase II δ (CaMKIIδ) Controls Neointima Formation after Carotid Ligation and Vascular Smooth Muscle Cell Proliferation through Cell Cycle Regulation by p21 by Li, Weiwei, Li, Hui, Sanders, Philip N., Mohler, Peter J., Backs, Johannes, Olson, Eric N., Anderson, Mark E., Grumbach, Isabella M.

“…The multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII) promotes vascular smooth muscle (VSMC) proliferation. However, the signaling pathways…”
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Behavioral Outcomes and Neural Network Modeling of a Novel, Putative, Recategorization Sound Therapy by Durai, Mithila, Doborjeh, Zohreh, Sanders, Philip J, Vajsakovic, Dunja, Wendt, Anne, Searchfield, Grant D

“…The mechanisms underlying sound's effect on tinnitus perception are unclear. Tinnitus activity appears to conflict with perceptual expectations of "real"…”
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Early detection and environmental drivers of sewage fungus outbreaks in rivers by Albini, Dania, Lester, Lauren, Sanders, Philip, Hughes, Jocelyne M. R., Jackson, Michelle C.

“…Abstract Sewage effluent is a major ongoing threat to water quality and biodiversity in freshwater environments. It can cause outbreaks of sewage fungus…”
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The multifunctional Ca2+/calmodulin-dependent kinase II regulates vascular smooth muscle migration through matrix metalloproteinase 9 by Scott, Jason A, Xie, Litao, Li, Hui, Li, Weiwei, He, Julie B, Sanders, Philip N, Carter, A Brent, Backs, Johannes, Anderson, Mark E, Grumbach, Isabella M

“…The multifunctional CaMKII has been implicated in vascular smooth muscle cell (VSMC) migration, but little is known regarding its downstream targets that…”
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Prediction of Acoustic Residual Inhibition of Tinnitus Using a Brain-Inspired Spiking Neural Network Model by Sanders, Philip J, Doborjeh, Zohreh G, Doborjeh, Maryam G, Kasabov, Nikola K, Searchfield, Grant D

“…Auditory Residual Inhibition (ARI) is a temporary suppression of tinnitus that occurs in some people following the presentation of masking sounds. Differences…”
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CaMKII is essential for the proasthmatic effects of oxidation by Sanders, Philip N, Koval, Olha M, Jaffer, Omar A, Prasad, Anand M, Businga, Thomas R, Scott, Jason A, Hayden, Patrick J, Luczak, Elizabeth D, Dickey, David D, Allamargot, Chantal, Olivier, Alicia K, Meyerholz, David K, Robison, Alfred J, Winder, Danny G, Blackwell, Timothy S, Dworski, Ryszard, Sammut, David, Wagner, Brett A, Buettner, Garry R, Pope, Robert M, Miller, Jr, Francis J, Dibbern, Megan E, Haitchi, Hans Michael, Mohler, Peter J, Howarth, Peter H, Zabner, Joseph, Kline, Joel N, Grumbach, Isabella M, Anderson, Mark E

“…Increased reactive oxygen species (ROS) contribute to asthma, but little is known about the molecular mechanisms connecting increased ROS with characteristic…”
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Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice[S] by Mannerås-Holm, Louise, Schönke, Milena, Brozinick, Joseph T., Vetterli, Laurène, Bui, Hai-Hoang, Sanders, Philip, Nascimento, Emmani B.M., Björnholm, Marie, Chibalin, Alexander V., Zierath, Juleen R.

“…Diacylglycerol kinases (DGKs) catalyze the phosphorylation and conversion of diacylglycerol (DAG) into phosphatidic acid. DGK isozymes have unique primary…”
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An implementation science systematic review of neurophysiological evidence indicates the tinnitus core network as a therapeutic target by Burton-Harris, Lisa Jane, Sanders, Philip Julian, Searchfield, Grant D.

“…Identifying and implementing an effective tinnitus treatment has been a challenge. Despite efforts over many decades, there is no definitive cure for tinnitus…”
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Diagnostic Accuracy of Serum, Synovial, and Tissue Testing for Chronic Periprosthetic Joint Infection After Hip and Knee Replacements: A Systematic Review by Carli, Alberto V., Abdelbary, Hesham, Ahmadzai, Nadera, Cheng, Wei, Shea, Beverley, Hutton, Brian, Sniderman, Jhase, Philip Sanders, Brendan Scott, Esmaeilisaraji, Leila, Skidmore, Becky, Gauthier-Kwan, Olivier Y., Bunting, Alexandra Catherine, Gauthier, Paul, Crnic, Agnes, Logishetty, Kartik, Moher, David, Fergusson, Dean, Beaulé, Paul E.

“…Chronic periprosthetic joint infection (PJI) is a devastating complication that can occur following total joint replacement. Patients with chronic PJI report a…”
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The combined effects of treated sewage discharge and land use on rivers by Albini, Dania, Lester, Lauren, Sanders, Philip, Hughes, Jocelyne, Jackson, Michelle C

“…Freshwater ecosystems are increasingly threatened by multiple anthropogenic stressors. Release of treated sewage effluent and pollution from agricultural or…”
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