Search Results - "Sanders, Jeremy K M"
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1
Evolution of Dynamic Combinatorial Chemistry
Published in Accounts of chemical research (18-12-2012)“…Since its inception in the mid-1990s, dynamic combinatorial chemistry (DCC), the chemistry of complex systems under thermodynamic control, has proved valuable…”
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2
Discovery of an Organic Trefoil Knot
Published in Science (American Association for the Advancement of Science) (09-11-2012)“…Molecular knots remain difficult to produce using the current synthetic methods of chemistry because of their topological complexity. We report here the…”
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3
Changing the game of time resolved X-ray diffraction on the mechanochemistry playground by downsizing
Published in Nature communications (21-10-2021)“…Time resolved in situ (TRIS) monitoring has revolutionised the study of mechanochemical transformations but has been limited by available data quality. Here we…”
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4
Homochiral and meso Figure Eight Knots and a Solomon Link
Published in Journal of the American Chemical Society (11-06-2014)“…A homochiral naphthalenediimide-based building block forms in water a disulfide library of macrocycles containing topological isomers. We attempted to identify…”
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5
Generation of a Dynamic System of Three-Dimensional Tetrahedral Polycatenanes
Published in Angewandte Chemie International Edition (27-05-2013)“…Seven of the best: A dynamic combinatorial library of polycatenated tetrahedra was prepared by complexation between a dynamic Fe4L6 tetrahedral cage,…”
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6
Discovery of Linear Receptors for Multiple Dihydrogen Phosphate Ions Using Dynamic Combinatorial Chemistry
Published in Journal of the American Chemical Society (23-03-2011)“…We describe the use of dynamic combinatorial chemistry to discover a new series of linear hydrazone-based receptors that bind multiple dihydrogen phosphate…”
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Thermodynamics of Supramolecular Naphthalenediimide Nanotube Formation: The Influence of Solvents, Side Chains, and Guest Templates
Published in Journal of the American Chemical Society (11-01-2012)“…Amino-acid functionalized naphthalenediimides self-assemble into hydrogen-bonded supramolecular helical nanotubes via a noncooperative, isodesmic process; the…”
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Exploring the Formation Pathways of Donor−Acceptor Catenanes in Aqueous Dynamic Combinatorial Libraries
Published in Journal of the American Chemical Society (09-03-2011)“…The discovery through dynamic combinatorial chemistry (DCC) of a new generation of donor−acceptor [2]catenanes highlights the power of DCC to access…”
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9
Understanding the unexpected effect of frequency on the kinetics of a covalent reaction under ball-milling conditions
Published in Beilstein journal of organic chemistry (2019)“…We here explore how ball-mill-grinding frequency affects the kinetics of a disulfide exchange reaction. Our kinetic data show that the reaction progress is…”
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10
Direct Observation of Intermediates in a Thermodynamically Controlled Solid-State Dynamic Covalent Reaction
Published in Journal of the American Chemical Society (19-11-2014)“…We present the first polymorph interconversion study that uses solid-state dynamic covalent chemistry (DCC). This system exhibits unexpected and rich behavior,…”
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11
Structural Parameters Governing the Dynamic Combinatorial Synthesis of Catenanes in Water
Published in Journal of the American Chemical Society (21-11-2012)“…We report the first dynamic combinatorial synthesis in water of an all-acceptor [2]catenane and of different types of donor–acceptor [2] and [3]catenanes…”
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12
Templated Dynamic Synthesis of a [3]Catenane
Published in Angewandte Chemie International Edition (06-02-2012)“…Three rings: The self‐assembly of a water‐soluble [3]catenane from a library composed of two linear building blocks, both terminated by cysteine components, is…”
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13
Amplification of Acetylcholine-Binding Catenanes from Dynamic Combinatorial Libraries
Published in Science (American Association for the Advancement of Science) (29-04-2005)“…Directed chemical synthesis can produce a vast range of molecular structures, but the intended product must be known at the outset. In contrast, evolution in…”
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14
Selection and Amplification of Hosts from Dynamic Combinatorial Libraries of Macrocyclic Disulfides
Published in Science (American Association for the Advancement of Science) (26-07-2002)“…We have discovered two receptors for two different guests from a single dynamic combinatorial library. Each of the two guests amplifies the formation of a…”
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Exploring the Differential Recognition of DNA G-Quadruplex Targets by Small Molecules Using Dynamic Combinatorial Chemistry
Published in Angewandte Chemie (International ed.) (01-01-2008)“…Tuning affinities: Dynamic combinatorial chemistry has been employed to explore the effect of chemical modifications on the DNA G‐quadruplex binding properties…”
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16
Diastereoselective Amplification of an Induced-Fit Receptor from a Dynamic Combinatorial Library
Published in Journal of the American Chemical Society (29-06-2005)“…A high-affinity, induced-fit receptor for NMe4I was discovered using dynamic combinatorial chemistry. The addition of the guest to a dynamic combinatorial…”
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17
Substituent effects on aromatic interactions in water
Published in Chemical science (Cambridge) (14-06-2023)“…Molecular recognition in water involves contributions due to polar functional group interactions, partial desolvation of polar and non-polar surfaces and…”
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Understanding the Influence of Surface Solvation and Structure on Polymorph Stability: A Combined Mechanochemical and Theoretical Approach
Published in Journal of the American Chemical Society (12-12-2018)“…We explore the effect of solvent concentration on the thermodynamic stability of two polymorphs of a 1:1 cocrystal of theophylline and benzamide subjected to…”
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Dynamic Combinatorial Chemistry
Published in Chemical reviews (01-09-2006)“…Dynamic combinatorial chemistry is defined as combinatorial chemistry under thermodynamic control. One application, which this review discusses, is the…”
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Aromatic interactions with heterocycles in water
Published in Chemical science (Cambridge) (18-10-2023)“…Conformationally well-defined supramolecular complexes that can be studied in different solvents provide a platform for separating and quantifying free energy…”
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