Search Results - "Sanders, E"

Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection by Lehmann, Brian D, Jovanović, Bojana, Chen, Xi, Estrada, Monica V, Johnson, Kimberly N, Shyr, Yu, Moses, Harold L, Sanders, Melinda E, Pietenpol, Jennifer A

“…Triple-negative breast cancer (TNBC) is a heterogeneous disease that can be classified into distinct molecular subtypes by gene expression profiling…”
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Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease by Bianchini, Giampaolo, Balko, Justin M., Mayer, Ingrid A., Sanders, Melinda E., Gianni, Luca

“…Key Points The routine diagnosis of triple-negative breast cancer (TNBC) depends on the accurate assessment of the status of the oestrogen receptor (ER),…”
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The effect of hearing aids on cognitive function: A systematic review by Sanders, Maxime E, Kant, Ellen, Smit, Adriana L, Stegeman, Inge

“…Dementia currently affects 50 million people globally with this expected to triple by 2050. Even though hearing loss is associated with cognitive decline, the…”
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Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies by Lehmann, Brian D, Bauer, Joshua A, Chen, Xi, Sanders, Melinda E, Chakravarthy, A Bapsi, Shyr, Yu, Pietenpol, Jennifer A

“…Triple-negative breast cancer (TNBC) is a highly diverse group of cancers, and subtyping is necessary to better identify molecular-based therapies. In this…”
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Establishing the clinical utility of autofluorescence spectroscopy for parathyroid detection by McWade, Melanie A., MS, Sanders, Melinda E., MD, Broome, James T., MD, Solórzano, Carmen C., MD, Mahadevan-Jansen, Anita, PhD

“…Background The inability of surgeons to identify parathyroid glands accurately during cervical endocrine surgery hinders patients from achieving postoperative…”
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Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data by Finotello, Francesca, Mayer, Clemens, Plattner, Christina, Laschober, Gerhard, Rieder, Dietmar, Hackl, Hubert, Krogsdam, Anne, Loncova, Zuzana, Posch, Wilfried, Wilflingseder, Doris, Sopper, Sieghart, Ijsselsteijn, Marieke, Brouwer, Thomas P, Johnson, Douglas, Xu, Yaomin, Wang, Yu, Sanders, Melinda E, Estrada, Monica V, Ericsson-Gonzalez, Paula, Charoentong, Pornpimol, Balko, Justin, de Miranda, Noel Filipe da Cunha Carvalho, Trajanoski, Zlatko

“…We introduce quanTIseq, a method to quantify the fractions of ten immune cell types from bulk RNA-sequencing data. quanTIseq was extensively validated in blood…”
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MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation by Lee, Kyung-min, Giltnane, Jennifer M., Balko, Justin M., Schwarz, Luis J., Guerrero-Zotano, Angel L., Hutchinson, Katherine E., Nixon, Mellissa J., Estrada, Mónica V., Sánchez, Violeta, Sanders, Melinda E., Lee, Taekyu, Gómez, Henry, Lluch, Ana, Pérez-Fidalgo, J. Alejandro, Wolf, Melissa Magdalene, Andrejeva, Gabriela, Rathmell, Jeffrey C., Fesik, Stephen W., Arteaga, Carlos L.

“…Most patients with advanced triple-negative breast cancer (TNBC) develop drug resistance. MYC and MCL1 are frequently co-amplified in drug-resistant TNBC after…”
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Multi-omics analysis identifies therapeutic vulnerabilities in triple-negative breast cancer subtypes by Lehmann, Brian D., Colaprico, Antonio, Silva, Tiago C., Chen, Jianjiao, An, Hanbing, Ban, Yuguang, Huang, Hanchen, Wang, Lily, James, Jamaal L., Balko, Justin M., Gonzalez-Ericsson, Paula I., Sanders, Melinda E., Zhang, Bing, Pietenpol, Jennifer A., Chen, X. Steven

“…Triple-negative breast cancer (TNBC) is a collection of biologically diverse cancers characterized by distinct transcriptional patterns, biology, and immune…”
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Features of COVID-19 post-infectious cytokine release syndrome in children presenting to the emergency department by Waltuch, Temima, Gill, Prakriti, Zinns, Lauren E., Whitney, Rachel, Tokarski, Julia, Tsung, James W., Sanders, Jennifer E.

“…The 2019 coronavirus disease (COVID-19) has not appeared to affect children as severely as adults. However, approximately 1 month after the COVID-19 peak in…”
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THE METALLICITY PROFILE OF M31 FROM SPECTROSCOPY OF HUNDREDS OF H II REGIONS AND PNe by Sanders, Nathan E, Caldwell, Nelson, McDowell, Jonathan, Harding, Paul

“…The oxygen abundance gradients among nebular emission line regions in spiral galaxies have been used as important constraints for models of chemical evolution…”
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Growth hormone, insulin-like growth factor-1 and the aging brain by Ashpole, Nicole M., Sanders, Jessica E., Hodges, Erik L., Yan, Han, Sonntag, William E.

“…Growth hormone (GH) and insulin-like growth factor (IGF)-1 regulate the development and function of cells throughout the body. Several clinical diseases that…”
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DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer by Luo, Na, Nixon, Mellissa J., Gonzalez-Ericsson, Paula I., Sanchez, Violeta, Opalenik, Susan R., Li, Huili, Zahnow, Cynthia A., Nickels, Michael L., Liu, Fei, Tantawy, Mohammed N., Sanders, Melinda E., Manning, H. Charles, Balko, Justin M.

“…Potentiating anti-tumor immunity by inducing tumor inflammation and T cell-mediated responses are a promising area of cancer therapy. Immunomodulatory agents…”
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Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy by Johnson, Douglas B., Estrada, Monica V., Salgado, Roberto, Sanchez, Violeta, Doxie, Deon B., Opalenik, Susan R., Vilgelm, Anna E., Feld, Emily, Johnson, Adam S., Greenplate, Allison R., Sanders, Melinda E., Lovly, Christine M., Frederick, Dennie T., Kelley, Mark C., Richmond, Ann, Irish, Jonathan M., Shyr, Yu, Sullivan, Ryan J., Puzanov, Igor, Sosman, Jeffrey A., Balko, Justin M.

“…Anti-PD-1 therapy yields objective clinical responses in 30–40% of advanced melanoma patients. Since most patients do not respond, predictive biomarkers to…”
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Optimal and continuous multilattice embedding by Sanders, E D, Pereira, A, Paulino, G H

“…Because of increased geometric freedom at a widening range of length scales and access to a growing material space, additive manufacturing has spurred renewed…”
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Anatomy of STEM teaching in North American universities by Stains, M, Harshman, J, Barker, M K, Chasteen, S V, Cole, R, DeChenne-Peters, S E, Eagan, Jr, M K, Esson, J M, Knight, J K, Laski, F A, Levis-Fitzgerald, M, Lee, C J, Lo, S M, McDonnell, L M, McKay, T A, Michelotti, N, Musgrove, A, Palmer, M S, Plank, K M, Rodela, T M, Sanders, E R, Schimpf, N G, Schulte, P M, Smith, M K, Stetzer, M, Van Valkenburgh, B, Vinson, E, Weir, L K, Wendel, P J, Wheeler, L B, Young, A M

“…Lecture is prominent, but practices vary A large body of evidence demonstrates that strategies that promote student interactions and cognitively engage…”
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Evolution of sex-specific traits through changes in HOX-dependent doublesex expression by Tanaka, Kohtaro, Barmina, Olga, Sanders, Laura E, Arbeitman, Michelle N, Kopp, Artyom

“…Almost every animal lineage is characterized by unique sex-specific traits, implying that such traits are gained and lost frequently in evolution. However, the…”
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Plasmonic Nanolaser Using Epitaxially Grown Silver Film by Lu, Yu-Jung, Kim, Jisun, Chen, Hung-Ying, Wu, Chihhui, Dabidian, Nima, Sanders, Charlotte E., Wang, Chun-Yuan, Lu, Ming-Yen, Li, Bo-Hong, Qiu, Xianggang, Chang, Wen-Hao, Chen, Lih-Juann, Shvets, Gennady, Shih, Chih-Kang, Gwo, Shangjr

“…A nanolaser is a key component for on-chip optical communications and computing systems. Here, we report on the low-threshold, continuous-wave operation of a…”
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Measles outbreak in complex emergency: estimating vaccine effectiveness and evaluation of the vaccination campaign in Borno State, Nigeria, 2019 by Jean Baptiste, Anne Eudes, Wagai, John, Luce, Richard, Masresha, Balcha, Klinkenberg, Don, Veldhuijzen, Irene, Oteri, Joseph, Dieng, Boubacar, Ikeonu, Obianuju Caroline, Meleh, Sule, Musa, Audu, Braka, Fiona, Hahné, Susan, Sanders, E A M, Hak, Eelko

“…From January to May 2019, large measles outbreaks affected Nigeria. Borno state was the most affected, recording 15,237 suspected cases with the state capital…”
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Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer by Jansen, Valerie M, Bhola, Neil E, Bauer, Joshua A, Formisano, Luigi, Lee, Kyung-Min, Hutchinson, Katherine E, Witkiewicz, Agnieszka K, Moore, Preston D, Estrada, Mónica Valéria, Sánchez, Violeta, Ericsson, Paula G, Sanders, Melinda E, Pohlmann, Paula R, Pishvaian, Michael J, Riddle, David A, Dugger, Teresa C, Wei, Wenyi, Knudsen, Erik S, Arteaga, Carlos L

“…Acquired resistance to cyclin-dependent kinases 4 and 6 (CDK4/6) small-molecule inhibitors in breast cancer arises through mechanisms that are yet…”
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Targeted Memory Reactivation During Sleep Improves Next-Day Problem Solving by Sanders, Kristin E. G., Osburn, Samuel, Paller, Ken A., Beeman, Mark

“…Many people have claimed that sleep has helped them solve a difficult problem, but empirical support for this assertion remains tentative. The current…”
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