Search Results - "Sanders, Brittany R."

Genotype-by-environment interactions govern fitness changes associated with adaptive mutations in two-component response systems by Sanders, Brittany R, Miller, Jordan E, Ahmidouch, Noor, Graves, Jr, Joseph L, Thomas, Misty D

“…Two-component response systems (TCRS) are the main mechanism by which prokaryotes acclimate to changing environments. These systems are composed of a membrane…”
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It Takes Two to Make a Thing Go Right: Epistasis, Two-Component Response Systems, and Bacterial Adaptation by Sanders, Brittany R, Thomas, Lauren S, Lewis, Naya M, Ferguson, Zaria A, Graves, Jr, Joseph L, Thomas, Misty D

“…Understanding the interplay between genotype and fitness is a core question in evolutionary biology. Here, we address this challenge in the context of…”
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Long-Term Recovery of the Adaptive Immune System in Rhesus Macaques After Total Body Irradiation by Macintyre, Andrew N., French, Matthew J., Sanders, Brittany R., Riebe, Kristina J., Shterev, Ivo D., Wiehe, Kevin, Hora, Bhavna, Evangelous, Tyler, Dugan, Greg, Bourland, J. Daniel, Cline, J. Mark, Sempowski, Gregory D.

“…Ionizing radiation causes acute damage to hematopoietic and immune cells, but the long-term immunologic consequences of irradiation are poorly understood. We…”
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Long-Term Immunological Consequences of Radiation Exposure in a Diverse Cohort of Rhesus Macaques by French, Matthew J., Wuerker, Ryan, Dugan, Greg, Olson, John D., Sanders, Brittany R., Tooze, Janet A., Caudell, David L., Cline, J. Mark, Sempowski, Gregory D., Macintyre, Andrew N.

“…The aim of this study was to develop an improved understanding of the delayed immunologic effects of acute total body irradiation (TBI) using a diverse cohort…”
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Reporting off-target effects of recombinant engineering using the pORTMAGE system by Sanders, Brittany R., Townsend, Sydney E., Ford, Maria L., Graves, Joseph L., Thomas, Misty D.

“…pORTMAGE recombineering is a simple technique for incorporation of novel point mutations into bacterial genomes that eliminates off-target effects. Here we…”
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