Search Results - "Sandbulte, Matthew R"

Discordant antigenic drift of neuraminidase and hemagglutinin in H1N1 and H3N2 influenza viruses by Sandbulte, Matthew R, Westgeest, Kim B, Gao, Jin, Xu, Xiyan, Klimov, Alexander I, Russell, Colin A, Burke, David F, Smith, Derek J, Fouchier, Ron A. M, Eichelberger, Maryna C

“…Seasonal epidemics caused by influenza virus are driven by antigenic changes (drift) in viral surface glycoproteins that allow evasion from preexisting humoral…”
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Contribution of antibody production against neuraminidase to the protection afforded by influenza vaccines by Marcelin, Glendie, Sandbulte, Matthew R., Webby, Richard J.

“…SUMMARY Vaccines are instrumental in controlling the burden of influenza virus infection in humans and animals. Antibodies raised against both major viral…”
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Live Attenuated Influenza Vaccine Provides Superior Protection from Heterologous Infection in Pigs with Maternal Antibodies without Inducing Vaccine-Associated Enhanced Respiratory Disease by VINCENT, Amy L, WENJUN MA, LAGER, Kelly M, RICHT, Jürgen A, JANKE, Bruce H, SANDBULTE, Matthew R, GAUGER, Philip C, LOVING, Crystal L, WEBBY, Richard J, GARCIA-SASTRE, Adolfo

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cross-reactive neuraminidase antibodies afford partial protection against H5N1 in mice and are present in unexposed humans by Sandbulte, Matthew R, Jimenez, Gretchen S, Boon, Adrianus C M, Smith, Larry R, Treanor, John J, Webby, Richard J

“…A pandemic H5N1 influenza outbreak would be facilitated by an absence of immunity to the avian-derived virus in the human population. Although this condition…”
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Optimal Use of Vaccines for Control of Influenza A Virus in Swine by Sandbulte, Matthew R, Spickler, Anna R, Zaabel, Pamela K, Roth, James A

“…Influenza A virus in swine (IAV-S) is one of the most important infectious disease agents of swine in North America. In addition to the economic burden of…”
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Inactivated Seasonal Influenza Vaccines Increase Serum Antibodies to the Neuraminidase of Pandemic Influenza A(H1N1) 2009 Virus in an Age-Dependent Manner by Marcelin, Glendie, Bland, Hilliary M., Negovetich, Nicholas J., Sandbulte, Matthew R., Ellebedy, Ali H., Webb, Ashley D., Griffin, Yolanda S., DeBeauchamp, Jennifer L., McElhaney, Janet E., Webby, Richard J.

“…Levels of preexisting antibodies to the hemagglutinin of pandemic influenza A(H1N1) 2009 (hereafter pandemic H1N1) virus positively correlate with age. The…”
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Role of terrestrial wild birds in ecology of influenza A virus (H5N1) by Boon, Adrianus C M, Sandbulte, Matthew R, Seiler, Patrick, Webby, Richard J, Songserm, Thaweesak, Guan, Yi, Webster, Robert G

“…House sparrows, European starlings, and Carneux pigeons were inoculated with 4 influenza A (H5N1) viruses isolated from different avian species. We monitored…”
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Infant HIV testing at birth using point-of-care and conventional HIV DNA PCR: an implementation feasibility pilot study in Kenya by Sandbulte, Matthew R, Gautney, Brad J, Maloba, May, Wexler, Catherine, Brown, Melinda, Mabachi, Natabhona, Goggin, Kathy, Lwembe, Raphael, Nazir, Niaman, Odeny, Thomas A, Finocchario-Kessler, Sarah

“…Infant HIV diagnosis by HIV DNA polymerase chain reaction (PCR) testing at the standard 6 weeks of age is often late to mitigate the mortality peak that occurs…”
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Predictors of Mortality Among HIV-exposed Infants Through 18 Months of Age in Kenya: A Retrospective Review of Programmatic Data by Sandbulte, Matthew R., Nazir, Niaman, Goggin, Kathy, Wexler, Catherine, Maloba, May, Gautney, Brad J., Khamadi, Samoel, Lwembe, Raphael, Finocchario-Kessler, Sarah

“…We identified mortality predictors among HIV-exposed uninfected infants and infants living with HIV in Kenyan early infant diagnosis services between 2012 and…”
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Vaccine-associated enhanced respiratory disease is influenced by haemagglutinin and neuraminidase in whole inactivated influenza virus vaccines by Rajão, Daniela S, Chen, Hongjun, Perez, Daniel R, Sandbulte, Matthew R, Gauger, Phillip C, Loving, Crystal L, Shanks, G Dennis, Vincent, Amy

“…Multiple subtypes and many antigenic variants of influenza A virus (IAV) co-circulate in swine in the USA, complicating effective use of commercial vaccines to…”
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The type of adjuvant in whole inactivated influenza a virus vaccines impacts vaccine-associated enhanced respiratory disease by Souza, Carine K., Rajão, Daniela S., Sandbulte, Matthew R., Lopes, Sara, Lewis, Nicola S., Loving, Crystal L., Gauger, Phillip C., Vincent, Amy L.

“…•The type of adjuvant in influenza vaccines impacted lung immunopathology with mismatched challenge virus.•Oil-in-water adjuvants induced potent homologous…”
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Neuraminidase inhibiting antibody responses in pigs differ between influenza A virus N2 lineages and by vaccine type by Sandbulte, Matthew R, Gauger, Phillip C, Kitikoon, Pravina, Chen, Hongjun, Perez, Daniel R, Roth, James A, Vincent, Amy L

“…Highlights • The NI responses in pigs vaccinated with LAIV, WIV or WT IAV were measured. • Vaccines induced strong NI responses, but was diminished in the…”
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Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory disease in weaned piglets by Rajao, Daniela S, Sandbulte, Matthew R, Gauger, Phillip C, Kitikoon, Pravina, Platt, Ratree, Roth, James A, Perez, Daniel R, Loving, Crystal L, Vincent, Amy L

“…Abstract Control of influenza A virus (IAV) in pigs is done by vaccination of females to provide maternally-derived antibodies (MDA) through colostrum. Our aim…”
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Divergent immune responses and disease outcomes in piglets immunized with inactivated and attenuated H3N2 swine influenza vaccines in the presence of maternally-derived antibodies by Sandbulte, Matthew R, Platt, Ratree, Roth, James A, Henningson, Jamie N, Gibson, Kathleen A, Rajão, Daniela S, Loving, Crystal L, Vincent, Amy L

“…Abstract Live-attenuated influenza virus (LAIV) prime-boost vaccination previously conferred protection against heterologous H3N2 swine influenza challenge,…”
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Vaccination with NS1-truncated H3N2 swine influenza virus primes T cells and confers cross-protection against an H1N1 heterosubtypic challenge in pigs by Kappes, Matthew A, Sandbulte, Matthew R, Platt, Ratree, Wang, Chong, Lager, Kelly M, Henningson, Jamie N, Lorusso, Alessio, Vincent, Amy L, Loving, Crystal L, Roth, James A, Kehrli, Marcus E

“…Highlights ► Attenuated H3N2 influenza vaccine with truncated NS1 was administered to pigs. ► Vaccine induced broadly reactive mucosal antibodies. ► Vaccine…”
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A miniaturized assay for influenza neuraminidase‐inhibiting antibodies utilizing reverse genetics‐derived antigens by Sandbulte, Matthew R., Gao, Jin, Straight, Timothy M., Eichelberger, Maryna C.

“…Background  Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely…”
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Analyzing swine sera for functional antibody titers against influenza A neuraminidase proteins using an enzyme-linked lectin assay (ELLA) by Sandbulte, Matthew R, Eichelberger, Maryna C

“…Neuraminidase (NA) is an envelope glycoprotein of influenza viruses, including swine-lineage influenza A viruses. NA possesses sialidase activity, which is…”
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Factors affecting induction of peripheral IFN-γ recall response to influenza A virus vaccination in pigs by Olson, Zahra F., Sandbulte, Matthew R., Souza, Carine Kunzler, Perez, Daniel R., Vincent, Amy L., Loving, Crystal L.

“…While T cell contribution to IAV immunity is appreciated, data comparing methods to evaluate IFN-γ production by IAV-specific T cells elicited following…”
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NFκB Negatively Regulates Interferon-induced Gene Expression and Anti-influenza Activity by Wei, Lai, Sandbulte, Matthew R., Thomas, Paul G., Webby, Richard J., Homayouni, Ramin, Pfeffer, Lawrence M.

“…Interferons (IFNs) are antiviral cytokines that selectively regulate gene expression through several signaling pathways including nuclear factor κB(NFκB). To…”
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Analysis of cytokine secretion from human plasmacytoid dendritic cells infected with H5N1 or low-pathogenicity influenza viruses by Sandbulte, Matthew R, Boon, Adrianus C.M, Webby, Richard J, Riberdy, Janice M

“…Abstract Mechanisms underlying the virulence of H5N1 influenza viruses in humans are poorly understood, though evidence of hyperinflammation and systemic viral…”
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