Search Results - "Sandborg, Holly"

Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing by Hiatt, Joseph B, Sandborg, Holly, Garrison, Sarah M, Arnold, Henry U, Liao, Sheng-You, Norton, Justin P, Friesen, Travis J, Wu, Feinan, Sutherland, Kate D, Rienhoff, Hugh Y, Martins, Renato, Houghton, A McGarry, Srivastava, Shivani, MacPherson, David

“…The addition of immune checkpoint blockade (ICB) to platinum/etoposide chemotherapy changed the standard of care for small cell lung cancer (SCLC) treatment…”
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A Cancer Cell-Intrinsic GOT2-PPARδ Axis Suppresses Antitumor Immunity by Abrego, Jaime, Sanford-Crane, Hannah, Oon, Chet, Xiao, Xu, Betts, Courtney B, Sun, Duanchen, Nagarajan, Shanthi, Diaz, Luis, Sandborg, Holly, Bhattacharyya, Sohinee, Xia, Zheng, Coussens, Lisa M, Tontonoz, Peter, Sherman, Mara H

“…Despite significant recent advances in precision medicine, pancreatic ductal adenocarcinoma (PDAC) remains near uniformly lethal. Although immune-modulatory…”
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NUFIP1+ stroma keeps PDAC fed by Sandborg, Holly, Sherman, Mara H.

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Abstract A025: Autotaxin-lysolipid signaling suppresses a CCL11- eosinophil axis to promote pancreatic cancer progression by Bhattacharyya, Sohinee, Oon, Chet, Sandborg, Holly, Morgan, Terry, Sherman, Mara H.

“…Abstract Among all cancer types, pancreatic ductal adenocarcinoma (PDAC) has one of the worst outcomes. In recent studies, metabolic and microenvironmental…”
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Autotaxin-lysolipid signaling suppresses a CCL11-eosinophil axis to promote pancreatic cancer progression by Bhattacharyya, Sohinee, Oon, Chet, Diaz, Luis, Sandborg, Holly, Stempinski, Erin S, Saoi, Michelle, Morgan, Terry K, López, Claudia S, Cross, Justin R, Sherman, Mara H

“…Lipids and their modifying enzymes regulate diverse features of the tumor microenvironment and cancer progression. The secreted enzyme autotaxin (ATX)…”
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Molecular phenotyping of small cell lung cancer using targeted cfDNA profiling of transcriptional regulatory regions by Hiatt, Joseph B, Doebley, Anna-Lisa, Arnold, Henry U, Adil, Mohamed, Sandborg, Holly, Persse, Thomas W, Ko, Minjeong, Wu, Feinan, Quintanal Villalonga, Alvaro, Santana-Davila, Rafael, Eaton, Keith, Dive, Caroline, Rudin, Charles M, Thomas, Anish, Houghton, A McGarry, Ha, Gavin, MacPherson, David

“…We report an approach for cancer phenotyping based on targeted sequencing of cell-free DNA (cfDNA) for small cell lung cancer (SCLC). In SCLC, differential…”
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