Search Results - "Sandberg, Anders"
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Hacking the Brain: Dimensions of Cognitive Enhancement
Published in ACS chemical neuroscience (20-03-2019)“…In an increasingly complex information society, demands for cognitive functioning are growing steadily. In recent years, numerous strategies to augment brain…”
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Stabilization of neurotoxic Alzheimer amyloid-β oligomers by protein engineering
Published in Proceedings of the National Academy of Sciences - PNAS (31-08-2010)“…Soluble oligomeric aggregates of the amyloid-β peptide (Aβ) have been implicated in the pathogenesis of Alzheimer's disease (AD). Although the conformation…”
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3
The Ethics of Volcano Geoengineering
Published in Earth's future (01-10-2023)“…Volcano geoengineering is the practice of altering the state of volcanic systems and/or volcanic eruptions to exploit them or mitigate their risk. Although…”
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Sustainability: We need to focus on overall system outcomes rather than simplistic targets
Published in People and nature (Hoboken, N.J.) (01-04-2024)“…Abstract Many of the global challenges that confront humanity are interlinked in a dynamic complex network, with multiple feedback loops, nonlinear…”
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Amyloid-β protofibrils: size, morphology and synaptotoxicity of an engineered mimic
Published in PloS one (2013)“…Structural and biochemical studies of the aggregation of the amyloid-β peptide (Aβ) are important to understand the mechanisms of Alzheimer's disease, but…”
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Aβ42 oligomer-specific antibody ALZ-201 reduces the neurotoxicity of Alzheimer's disease brain extracts
Published in Alzheimer's research & therapy (29-12-2022)“…In Alzheimer's disease (AD), amyloid-β 1-42 (Aβ42) neurotoxicity stems mostly from its soluble oligomeric aggregates. Studies of such aggregates have been…”
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Long-term cost-effectiveness of interventions for loss of electricity/industry compared to artificial general intelligence safety
Published in European journal of futures research (01-12-2021)“…Extreme solar storms, high-altitude electromagnetic pulses, and coordinated cyber attacks could disrupt regional/global electricity. Since electricity…”
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Protein Autoproteolysis: Conformational Strain Linked to the Rate of Peptide Cleavage by the pH Dependence of the N → O Acyl Shift Reaction
Published in Journal of the American Chemical Society (15-07-2009)“…Nucleophilic attack by a side chain nucleophile on the adjacent peptide bond followed by N → O or N → S acyl shift is the primary step in protein…”
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Pits, Peripheralization and the Politics of Scale: Struggles over Locating Extractive Industries in the Town of Caledon, Ontario, Canada
Published in Regional studies (01-05-2007)“…Chambers C. and Sandberg L. A. (2007) Pits, peripheralization and the politics of scale: struggles over locating extractive industries in the town of Caledon,…”
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Correction: Amyloid-β Protofibrils: Size, Morphology and Synaptotoxicity of an Engineered Mimic
Published in PloS one (25-10-2013)Get full text
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11
SEA Domain Autoproteolysis Accelerated by Conformational Strain: Mechanistic Aspects
Published in Journal of molecular biology (04-04-2008)“…A subclass of SEA (sea urchin sperm protein, enterokinase, and agrin) domain proteins undergoes autoproteolysis between glycine and serine in a conserved…”
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Reaping Nature's Dividends: The Neoliberalization and Gentrification of Nature on the Oak Ridges Moraine
Published in Journal of environmental policy & planning (01-03-2010)“…In this article, we follow the position that neoliberalism is not a state but a process of political, social, and economic development. We explore the…”
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Cognitive Enhancement: Methods, Ethics, Regulatory Challenges
Published in Science and engineering ethics (01-09-2009)“…Cognitive enhancement takes many and diverse forms. Various methods of cognitive enhancement have implications for the near future. At the same time, these…”
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14
More ties than we thought
Published in PeerJ (San Francisco, CA) (27-05-2015)“…We extend the existing enumeration of neck tie-knots to include tie-knots with a textured front, tied with the narrow end of a tie. These tie-knots have gained…”
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Friends or Foe? Invasive Species and Public Green Space in Toronto
Published in Geographical review (01-04-2004)“…Environmentalists and ecologists typically regard invasive species as ecologically detrimental and undesirable. Although the ecological impacts of invasive…”
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Competing claims in land-use policy: property development and mineral aggregates industries
Published in Journal of environmental planning and management (10-06-2022)“…This paper offers an empirically grounded understanding of the historical processes by which economic and institutional actors, particularly industry networks…”
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Cognitive aging as an extension of brain development: A model linking learning, brain plasticity, and neurodegeneration
Published in Mechanisms of ageing and development (01-10-2005)“…Differences in cognitive aging rates among mammals suggest that the pace of brain aging is genetically determined. In this work, we investigate the possibility…”
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Recombinant amyloid beta-peptide production by coexpression with an affibody ligand
Published in BMC biotechnology (30-10-2008)“…Oligomeric and fibrillar aggregates of the amyloid beta-peptide (Abeta) have been implicated in the pathogenesis of Alzheimer's disease (AD). The…”
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Ecocentrism and Biosphere Life Extension
Published in Science and engineering ethics (01-12-2022)“…The biosphere represents the global sum of all ecosystems. According to a prominent view in environmental ethics, ecocentrism, these ecosystems matter for…”
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There is plenty of time at the bottom: the economics, risk and ethics of time compression
Published in Foresight (Cambridge) (11-03-2019)“…Purpose The speed of computing and other automated processes plays an important role in how the world functions by causing “time compression”. This paper aims…”
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