Search Results - "Sancho, Aranzazu"

Longer intervals between SARS‐CoV‐2 infection and mRNA‐1273 doses improve the neutralization of different variants of concern by García‐Pérez, Javier, Bermejo, Mercedes, Ramírez‐García, Almudena, De La Torre‐Tarazona, Humberto Erick, Cascajero, Almudena, Castillo de la Osa, María, Jiménez, Paloma, Aparicio Gómez, Marta, Calonge, Esther, Sancho‐López, Aránzazu, Payares‐Herrera, Concepción, Layunta Acero, Rocio, Vicente‐Izquierdo, Laura, Avendaño‐Solá, Cristina, Alcamí, José, Pérez‐Olmeda, Mayte, Díez‐Fuertes, Francisco

“…The humoral immune response against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants of concern elicited by vaccination was evaluated in…”
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Evidence supporting regulatory-decision making on orphan medicinal products authorisation in Europe: methodological uncertainties by Pontes, Caridad, Fontanet, Juan Manuel, Vives, Roser, Sancho, Aranzazu, Gómez-Valent, Mònica, Ríos, José, Morros, Rosa, Martinalbo, Jorge, Posch, Martin, Koch, Armin, Roes, Kit, Oude Rengerink, Katrien, Torrent-Farnell, Josep, Torres, Ferran

“…To assess uncertainty in regulatory decision-making for orphan medicinal products (OMP), a summary of the current basis for approval is required; a systematic…”
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Empirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia: study protocol for a multicenter, open-label randomized controlled clinical trial by Rojo, Pablo, Moraleda, Cinta, Tagarro, Alfredo, Domínguez-Rodríguez, Sara, Castillo, Lola Madrid, Tato, Luis Manuel Prieto, López, Aranzazu Sancho, Manukyan, Lilit, Marcy, Olivier, Leroy, Valeriane, Nardone, Alessandra, Burger, David, Bassat, Quique, Bates, Matthew, Moh, Raoul, Iroh Tam, Pui-Ying, Mvalo, Tisungane, Magallhaes, Justina, Buck, W Chris, Sacarlal, Jahit, Musiime, Victor, Chabala, Chishala, Mujuru, Hilda Angela

“…Pneumonia is the primary cause of death among HIV-infected children in Africa, with mortality rates as high as 35-40% in infants hospitalized with severe…”
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EMA Review of Daratumumab (Darzalex) for the Treatment of Adult Patients Newly Diagnosed with Multiple Myeloma by Michaleas, Sotirios, Penninga, Elisabeth, Hovgaard, Doris, Dalseg, Anne‐Marie, Rosso, Aldana, Sarac, Sinan B., Jimenez, Jorge Camarero, Fernández, Lucia López‐Anglada, Fernández, Carolina Prieto, Mangas‐SanJuan, Victor, Garcia, Isabel, Payares‐Herrera, Concepcion, Sancho‐López, Aranzazu, Enzmann, Harald, Castro Lopes Silva, Marcia Sofia Sanches, Duarte, Sílvia, Pignatti, Francesco

“…The use of daratumumab in combination with established regimens for the treatment of newly diagnosed multiple myeloma has recently been authorized by the…”
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A randomized placebo controlled clinical trial to evaluate the efficacy and safety of minocycline in patients with Angelman syndrome (A-MANECE study) by Ruiz-Antoran, Belén, Sancho-López, Aranzazu, Cazorla-Calleja, Rosario, López-Pájaro, Luis Fernando, Leiva, Ágata, Iglesias-Escalera, Gema, Marín-Serrano, Maria Esperanza, Rincón-Ortega, Marta, Lara-Herguedas, Julián, Rossignoli-Palomeque, Teresa, Valiente-Rodríguez, Sara, González-Marques, Javier, Román-Riechmann, Enriqueta, Avendaño-Solá, Cristina

“…Minocycline is an old tetracycline antibiotic that has shown antiinflammatory and antiapoptotic properties in different neurological disease mouse models…”
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Applicability and added value of novel methods to improve drug development in rare diseases by Mitroiu, Marian, Rengerink, Katrien Oude, Pontes, Caridad, Sancho, Aranzazu, Vives, Roser, Pesiou, Stella, Fontanet, Juan Manuel, Torres, Ferran, Nikolakopoulos, Stavros, Pateras, Konstantinos, Rosenkranz, Gerd, Posch, Martin, Urach, Susanne, Ristl, Robin, Koch, Armin, Loukia, Spineli, van der Lee, Johanna H, Roes, Kit C B

“…The ASTERIX project developed a number of novel methods suited to study small populations. The objective of this exercise was to evaluate the applicability and…”
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Bronchopulmonary Penetration of Isavuconazole in Pulmonary Transplant Recipients (PBISA01): Protocol for a Phase IV Clinical Trial With a Single Treatment Arm by Darnaude-Ximénez, Ignacio, Caballero-Bermejo, Antonio F, Ruiz-Antorán, Belén, Aguilar-Pérez, Myriam, Gómez-López, Alicia, Sancho-López, Aranzazu, García-Fadul, Cristian, Diago-Sempere, Elena, Valle Falcones, Manuel, Ussetti-Gil, Piedad, Avendaño-Solá, Cristina

“…Aspergillosis is the most frequently observed invasive fungal disease (IFD) in lung transplant recipients. Isavuconazole (ISA) has shown a better safety…”
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CLINICAL RESEARCH AND DRUG REGULATION IN THE CHALLENGING TIMES OF INDIVIDUALIZED THERAPIES: A PIVOTAL ROLE OF CLINICAL PHARMACOLOGY by Gómez-Outes, Antonio, Sancho-López, Aránzazu, Carcas Sansuan, Antonio J, Avendaño-Solá, Cristina

“…Since the 1980s, medical specialists in Clinical Pharmacology have been playing a crucial role in the development of drug regulation in Spain. In this article…”
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Value contribution of cenobamate for the treatment of Focal-Onset Seizures (FOS) in patients with drug-resistant epilepsy (DRE) in Spain through reflective Multi-Criteria Decision Analysis (MCDA) by Falip, Mercè, López González, Francisco Javier, Martín-Herranz, Isabel, Merino-Bohórquez, Vicente, Montoya, Javier, Rey Gómez-Serranillos, Isabel, Rodriguez Uranga, Juan Jesús, Ruiz, Elías, Sancho-López, Aranzazu, Trillo Mata, Jose Luis, Antoni Vallès, Joan, Álvarez-Barón, Elena, Sabaniego, Joel, Subías-Labazuy, Silvia, Gil, Alicia

“…•Drug-resistant epilepsy (DRE) is considered a severe condition.•DRE is associated with important burden for patients and the healthcare system.•Cenobamate…”
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Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial by Caballero Bermejo, Antonio F, Ruiz-Antorán, Belén, Fernández Cruz, Ana, Diago Sempere, Elena, Callejas Díaz, Alejandro, Múñez Rubio, Elena, Avendaño-Solá, Cristina, Ramos Martínez, Antonio, Sancho López, Aránzazu

“…In some patients, acute, life-threatening respiratory injury produced by viruses such as SARS-CoV and other viral pneumonia are associated with an…”
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Evaluation of convalescent plasma versus standard of care for the treatment of COVID-19 in hospitalized patients: study protocol for a phase 2 randomized, open-label, controlled, multicenter trial by Diago-Sempere, Elena, Bueno, José Luis, Sancho-López, Aránzazu, Rubio, Elena Múñez, Torres, Ferrán, de Molina, Rosa Malo, Fernández-Cruz, Ana, de Diego, Isabel Salcedo, Velasco-Iglesias, Ana, Payares-Herrera, Concepción, Flecha, Inmaculada Casas, Avendaño-Solà, Cristina, Palomino, Rafael Duarte, Ramos-Martínez, Antonio, Ruiz-Antorán, Belén

“…COVID-19 is a respiratory disease caused by a novel coronavirus (SARS-CoV-2) and causes substantial morbidity and mortality. At the time this clinical trial…”
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Bronchopulmonary penetration of isavuconazole in lung transplant recipients by Caballero-Bermejo, Antonio F., Darnaude-Ximénez, Ignacio, Aguilar-Pérez, Myriam, Gomez-Lopez, Alicia, Sancho-López, Aránzazu, López García-Gallo, Cristina, Díaz Nuevo, Gema, Diago-Sempere, Elena, Ruiz-Antorán, Belén, Avendaño-Solá, Cristina, Ussetti-Gil, Piedad

“…Isavuconazole’s (ISA) pharmacokinetics was studied among lung transplant recipients to evaluate its bronchopulmonary penetration. This study included 13…”
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The Right Time for Steroids in COVID-19 by Fernández-Cruz, Ana, Ruiz-Antorán, Belén, Múñez-Rubio, Elena, Sancho-López, Aránzazu, Callejas-Díaz, Alejandro, Avendaño-Solá, Cristina, Ramos-Martínez, Antonio

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Clinical features and predictors of delayed neurological syndrome in carbon monoxide poisoning: the AMICO study by Caballero-Bermejo, Antonio F, Ruiz-Antoran, Belén, Ramio-Lluch, Cristina, Dueñas-Ruiz, Antonio, Pineda Torcuato, Álvaro, Homar-Amengual, Catalina, Guerrero-González, María E, Sancho López, Aránzazu, García-Hernández, Raquel, Rodríguez Miranda, Belén, Gispert-Ametller, M Angels, Dueñas-Laita, Antonio, Puiguriguer Ferrando, Jordi

“…To identify predictors for developing delayed neurological syndrome (DNS) after an initial episode of carbon monoxide (CO) poisoning in the interest of…”
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Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 AMeta-analysis by Shankar-Hari, M, Vale, CL, Godolphin, PJ, Fisher, D, Higgins, JPT, Spiga, F, Savovic, J, Tierney, J, Baron, G, Benbenishty, JS

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Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis by Shankar-Hari, Manu, Vale, Claire L, Godolphin, Peter J, Fisher, David, Higgins, Julian P. T, Spiga, Francesca, Savovic, Jelena, Tierney, Jayne, Baron, Gabriel, Benbenishty, Julie S, Berry, Lindsay R, Broman, Niklas, Cavalcanti, Alexandre Biasi, Colman, Roos, De Buyser, Stefanie L, Derde, Lennie P. G, Domingo, Pere, Omar, Sharifah Faridah, Fernandez-Cruz, Ana, Feuth, Thijs, Garcia, Felipe, Garcia-Vicuna, Rosario, Gonzalez-Alvaro, Isidoro, Gordon, Anthony C, Haynes, Richard, Hermine, Olivier, Horby, Peter W, Horick, Nora K, Kumar, Kuldeep, Lambrecht, Bart N, Landray, Martin J, Leal, Lorna, Lederer, David J, Lorenzi, Elizabeth, Mariette, Xavier, Merchante, Nicolas, Misnan, Nor Arisah, Mohan, Shalini V, Nivens, Michael C, Oksi, Jarmo, Perez-Molina, Jose A, Pizov, Reuven, Porcher, Raphael, Postma, Simone, Rajasuriar, Reena, Ramanan, Athimalaipet V, Ravaud, Philippe, Reid, Pankti D, Rutgers, Abraham, Sancho-Lopez, Aranzazu, Seto, Todd B, Sivapalasingam, Sumathi, Soin, Arvinder Singh, Staplin, Natalie, Stone, John H, Strohbehn, Garth W, Sunden-Cullberg, Jonas, Torre-Cisneros, Julian, Tsai, Larry W, van Hoogstraten, Hubert, van Meerten, Tom, Veiga, Viviane Cordeiro, Westerweel, Peter E, Murthy, Srinivas, Diaz, Janet V, Marshall, John C, Sterne, Jonathan A. C

“…IMPORTANCE: Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized for COVID-19 have variously reported benefit, no effect, and…”
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Activities of clinical pharmacologists across Europe: A survey by the European association of clinical pharmacology and therapeutics by Marquet, Pierre, Jouanjus, Emilie, Sáez-Peñataro, Joaquin, Sancho-Lopez, Aranzazu

“…Purpose In order to explore clinical pharmacology and therapeutics (CPT) teaching and practices across continental Europe, the European Association of Clinical…”
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Red blood cell distribution width as a marker of hyperinflammation and mortality in COVID-19 by Moreno-Torres, Víctor, Sánchez-Chica, Enrique, Castejón, Raquel, Caballero Bermejo, Antonio-Francisco, Mills, Patricia, Diago-Sempere, Elena, Rosado, Silvia, Sancho-López, Aránzazu, Vargas-Núñez, Juan-Antonio, Ruiz-Antorán, Belén, Fernández-Cruz, Ana

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A Response to: Letter to the Editor Regarding Combination of Tocilizumab and Steroids to Improve Mortality in Patients with Severe COVID-19 Infection: A Spanish, Multicenter, Cohort by Ruiz-Antorán, Belén, Sancho-López, Aránzazu, Torres, Ferrán, Fernández-Cruz, Ana

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A Retrospective Controlled Cohort Study of the Impact of Glucocorticoid Treatment in SARS-CoV-2 Infection Mortality by Fernández-Cruz, Ana, Ruiz-Antorán, Belén, Muñoz-Gómez, Ana, Sancho-López, Aránzazu, Mills-Sánchez, Patricia, Centeno-Soto, Gustavo Adolfo, Blanco-Alonso, Silvia, Javaloyes-Garachana, Laura, Galán-Gómez, Amy, Valencia-Alijo, Ángela, Gómez-Irusta, Javier, Payares-Herrera, Concepción, Morrás-Torre, Ignacio, Sánchez-Chica, Enrique, Delgado-Téllez-de-Cepeda, Laura, Callejas-Díaz, Alejandro, Ramos-Martínez, Antonio, Múñez-Rubio, Elena, Avendaño-Solá, Cristina

“…Evidence to support the use of steroids in coronavirus disease 2019 (COVID-19) pneumonia is lacking. We aim to determine the impact of steroid use for COVID-19…”
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