Search Results - "Sanchez Sanchez, Violeta"
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Xylose fermentation as a challenge for commercialization of lignocellulosic fuels and chemicals
Published in Biotechnology letters (01-04-2015)“…Fuel ethanol production from lignocellulosic materials is at a level where commercial biofuel production is becoming a reality. The solubilization of the…”
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2
RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors
Published in Clinical cancer research (15-03-2016)“…Tumor-infiltrating lymphocytes (TIL) in the residual disease (RD) of triple-negative breast cancers (TNBC) after neoadjuvant chemotherapy (NAC) are associated…”
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3
CRISPR EnAbled Trackable genome Engineering for isopropanol production in Escherichia coli
Published in Metabolic engineering (01-05-2017)“…Isopropanol is an important target molecule for sustainable production of fuels and chemicals. Increases in DNA synthesis and synthetic biology capabilities…”
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4
Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers
Published in Cancer research (Chicago, Ill.) (01-11-2018)“…Cancer immunotherapies that remove checkpoint restraints on adaptive immunity are gaining clinical momentum but have not achieved widespread success in breast…”
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5
DNA methyltransferase inhibition upregulates MHC-I to potentiate cytotoxic T lymphocyte responses in breast cancer
Published in Nature communications (16-01-2018)“…Potentiating anti-tumor immunity by inducing tumor inflammation and T cell-mediated responses are a promising area of cancer therapy. Immunomodulatory agents…”
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6
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy
Published in Nature communications (29-01-2016)“…Anti-PD-1 therapy yields objective clinical responses in 30–40% of advanced melanoma patients. Since most patients do not respond, predictive biomarkers to…”
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7
mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis
Published in PLoS genetics (01-07-2015)“…Akt phosphorylation is a major driver of cell survival, motility, and proliferation in development and disease, causing increased interest in upstream…”
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8
Familial clustering of bicuspid aortic valve and its relationship with aortic dilation in first-degree relatives
Published in Heart (British Cardiac Society) (01-04-2019)“…Bicuspid aortic valve (BAV) is the most common congenital heart disease. This study aimed to determine the prevalence rate of BAV in first-degree relatives…”
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9
Proximal aorta longitudinal strain predicts aortic root dilation rate and aortic events in Marfan syndrome
Published in European heart journal (01-07-2019)“…Life expectancy in Marfan syndrome patients has improved thanks to the early detection of aortic dilation and prophylactic aortic root surgery. Current…”
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10
Characteristics of 698 patients with dissociative seizures: A UK multicenter study
Published in Epilepsia (Copenhagen) (01-11-2019)“…Objective We aimed to characterize the demographics of adults with dissociative (nonepileptic) seizures, placing emphasis on distribution of age at onset,…”
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Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2 + Breast Cancer
Published in Cancer research (Chicago, Ill.) (15-06-2017)“…mutations are associated with resistance to HER2-targeted therapies. We previously showed that transgenic mammary tumors are resistant to the HER2 antibodies…”
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12
Spanish Registry of Acute Aortic Syndrome (RESA). Changes in therapeutic management and lower mortality in acute aortic syndrome
Published in Revista española de cardiología (English ed.) (01-10-2022)“…The Spanish Registry of Acute Aortic Syndrome (RESA) was launched in 2005 to identify the characteristics of acute aortic syndrome (AAS) in Spain. The aim of…”
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13
Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence
Published in Science translational medicine (13-04-2016)“…Amplifications at 9p24 have been identified in breast cancer and other malignancies, but the genes within this locus causally associated with oncogenicity or…”
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67 The occurrence of contaminated blood culture in paediatric unit in DGH, simple intervention to prevent cost and unnecessary treatment
Published in Archives of disease in childhood (17-08-2022)“…AimsMicro-organisms are present on the skin surface of patients, staff and the immediate patient environment which can result in contamination of blood…”
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15
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis
Published in Breast cancer research : BCR (30-06-2017)“…The importance of the mTOR complex 2 (mTORC2) signaling complex in tumor progression is becoming increasingly recognized. HER2-amplified breast cancers use…”
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16
Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy
Published in Nature communications (21-02-2024)“…The high potential of siRNAs to silence oncogenic drivers remains largely untapped due to the challenges of tumor cell delivery. Here, divalent…”
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Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival
Published in Cancer research (Chicago, Ill.) (01-04-2018)“…Small-molecule inhibitors of the mTORC2 kinase (torkinibs) have shown efficacy in early clinical trials. However, the torkinibs under study also inhibit the…”
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18
Atorvastatin Effect on Aortic Dilatation and Valvular Calcification Progression in Bicuspid Aortic Valve (BICATOR): A Randomized Clinical Trial
Published in Circulation (New York, N.Y.) (18-06-2024)“…Ascending aorta dilation and aortic valve degeneration are common complications in patients with bicuspid aortic valve. Several retrospective studies have…”
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Early Bidirectional Glenn Procedure as Initial Surgical Palliation for Functionally Univentricular Heart with Common Arterial Trunk
Published in World journal for pediatric & congenital heart surgery (01-01-2023)“…We report an unusual case of a 2-month-old baby with a diagnosis of common arterial trunk and double outlet right ventricle with a remote type ventricular…”
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Identification and Regulation of fusA, the Polyketide Synthase Gene Responsible for Fusarin Production in Fusarium fujikuroi
Published in Applied and Environmental Microbiology (01-10-2012)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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