Pediatric Hospitalizations Associated with 2009 Pandemic Influenza A (H1N1) in Argentina

In the global 2009 H1N1 influenza pandemic, children are particularly vulnerable to severe disease. During the winter (May through July 2009) in Buenos Aires, the death rate associated with 2009 H1N1 influenza in children was 10 times that associated with seasonal influenza in 2007 (1.1 vs. 0.1 per...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 362; no. 1; pp. 45 - 55
Main Authors:	Libster, Romina, Bugna, Jimena, Coviello, Silvina, Hijano, Diego R, Dunaiewsky, Mariana, Reynoso, Natalia, Cavalieri, Maria L, Guglielmo, Maria C, Areso, M. Soledad, Gilligan, Tomas, Santucho, Fernanda, Cabral, Graciela, Gregorio, Gabriela L, Moreno, Rina, Lutz, Maria I, Panigasi, Alicia L, Saligari, Liliana, Caballero, Mauricio T, Egües Almeida, Rodrigo M, Gutierrez Meyer, Maria E, Neder, Maria D, Davenport, Maria C, Del Valle, Maria P, Santidrian, Valeria S, Mosca, Guillermina, Garcia Domínguez, Mercedes, Alvarez, Liliana, Landa, Patricia, Pota, Ana, Boloñati, Norma, Dalamon, Ricardo, Sanchez Mercol, Victoria I, Espinoza, Marco, Peuchot, Juan Carlos, Karolinski, Ariel, Bruno, Miriam, Borsa, Ana, Ferrero, Fernando, Bonina, Angel, Ramonet, Margarita, Albano, Lidia C, Luedicke, Nora, Alterman, Elias, Savy, Vilma, Baumeister, Elsa, Chappell, James D, Edwards, Kathryn M, Melendi, Guillermina A, Polack, Fernando P
Format:	Journal Article
Language:	English
Published:	Waltham, MA Massachusetts Medical Society 07-01-2010
Subjects:	Adolescent Age Distribution Argentina - epidemiology Biological and medical sciences Catchment areas Child Child, Preschool Children Comorbidity Death Disease control Disease Outbreaks Female Fever General aspects Hospitalization - statistics & numerical data Hospitals Human viral diseases Humans Hypoxemia Hypoxia - etiology Hypoxia - mortality Infant Infant, Newborn Infants Infectious diseases Influenza A Influenza A Virus, H1N1 Subtype Influenza, Human - classification Influenza, Human - complications Influenza, Human - epidemiology Influenza, Human - mortality Laboratories Male Mechanical ventilation Medical sciences Miscellaneous Mortality Pandemics Pediatrics Pneumonia, Bacterial - epidemiology Pneumonia, Bacterial - etiology Public health. Hygiene Public health. Hygiene-occupational medicine Respiratory tract Severity of Illness Index Staphylococcus - isolation & purification Streptococcus pneumoniae - isolation & purification Swine flu Vaccines Viral diseases Viral diseases of the respiratory system and ent viral diseases Viruses South America Argentina America United States > US Mexico Human Infection 2009 Medicine Pediatrics Association Viral disease Influenza A Hospitalization Child Public health
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Summary:	In the global 2009 H1N1 influenza pandemic, children are particularly vulnerable to severe disease. During the winter (May through July 2009) in Buenos Aires, the death rate associated with 2009 H1N1 influenza in children was 10 times that associated with seasonal influenza in 2007 (1.1 vs. 0.1 per 100,000 children). During the winter (May through July 2009) in Buenos Aires, the death rate associated with 2009 H1N1 influenza in children was 10 times that associated with seasonal influenza in 2007. Three times in the past century, pandemic influenza viruses have circulated globally and caused increased morbidity and mortality among persons who were not generally at risk for severe seasonal influenza. 1 In March 2009, a new strain of pandemic influenza A (H1N1) virus emerged in Mexico, where it caused extensive disease in young adults, 2 , 3 and was associated with increased morbidity in the United States. 4 , 5 The 2009 H1N1 virus spread rapidly across the Southern Hemisphere. 6 , 7 Morbidity and mortality were particularly high in Argentina, with numbers of confirmed cases and deaths second only to those in the United States. Although . . .
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa0907673