Search Results - "Sanchez Granel, Maria L."
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A novel Tetrahymena thermophila sterol C-22 desaturase belongs to the fatty acid hydroxylase/desaturase superfamily
Published in The Journal of biological chemistry (01-10-2022)“…Sterols in eukaryotic cells play important roles in modulating membrane fluidity and in cell signaling and trafficking. During evolution, a combination of gene…”
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Gene identification and functional characterization of a Δ12 fatty acid desaturase in Tetrahymena thermophila and its influence in homeoviscous adaptation to low temperature
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-11-2019)“…Homeoviscous adaptation in poikilotherms is based in the regulation of the level of desaturation of fatty acids, variation in phospholipids head groups and…”
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Phylogenomic analysis of integral diiron membrane histidine motif-containing enzymes in ciliates provides insights into their function and evolutionary relationships
Published in Molecular phylogenetics and evolution (01-09-2017)“…[Display omitted] •High diversity of non-heme IMHME has been identified in seven ciliates genomes.•Gene expansion, reduction and HGT events have modify the…”
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Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5α-reductase in the dorsal spinal cord of animals with neuropathic pain: Effects of progesterone administration
Published in Neuroscience letters (15-06-2016)“…•Spinal cord injury (SCI) induces an early increase in TSPO and 5α-RII mRNA levels.•A later decrease in 5α-RI and 5α-RII expression after SCI is observed.•TSPO…”
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Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5alpha-reductase in the dorsal spinal cord of animals with neuropathic pain: Effects of progesterone administration
Published in Neuroscience letters (2016)“…Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of…”
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