Search Results - "Sanchez Cardenas, Claudia"
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Biphasic Role of Calcium in Mouse Sperm Capacitation Signaling Pathways
Published in Journal of cellular physiology (01-08-2015)“…Mammalian sperm acquire fertilizing ability in the female tract in a process known as capacitation. At the molecular level, capacitation is associated with…”
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2
The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm
Published in Development (Cambridge) (01-07-2016)“…Sperm capacitation is required for fertilization. At the molecular level, this process is associated with fast activation of protein kinase A. Downstream of…”
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3
Compartmentalization of Distinct cAMP Signaling Pathways in Mammalian Sperm
Published in The Journal of biological chemistry (06-12-2013)“…Fertilization competence is acquired in the female tract in a process known as capacitation. Capacitation is needed for the activation of motility (e.g…”
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4
Super-resolution imaging of live sperm reveals dynamic changes of the actin cytoskeleton during acrosomal exocytosis
Published in Journal of cell science (01-11-2018)“…Filamentous actin (F-actin) is a key factor in exocytosis in many cell types. In mammalian sperm, acrosomal exocytosis (denoted the acrosome reaction or AR), a…”
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5
Membrane hyperpolarization abolishes calcium oscillations that prevent induced acrosomal exocytosis in human sperm
Published in The FASEB journal (01-06-2021)“…Sperm capacitation is essential to gain fertilizing capacity. During this process, a series of biochemical and physiological modifications occur that allow…”
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6
Acrosome reaction and Ca²⁺ imaging in single human spermatozoa: new regulatory roles of [Ca²⁺]i
Published in Biology of reproduction (01-09-2014)“…The spermatozoa acrosome reaction (AR) is essential for mammalian fertilization. Few methods allow visualization of AR in real time together with Ca²⁺ imaging…”
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7
Role of calcium oscillations in sperm physiology
Published in BioSystems (01-11-2021)“…Intracellular Ca2+ is a key regulator of cell signaling and sperm are not the exception. Cells often use cytoplasmic Ca2+ concentration ([Ca2+]i) oscillations…”
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8
A Specific Transitory Increase in Intracellular Calcium Induced by Progesterone Promotes Acrosomal Exocytosis in Mouse Sperm
Published in Biology of reproduction (01-03-2016)“…During capacitation, sperm acquire the ability to undergo the acrosome reaction (AR), an essential step in fertilization. Progesterone produced by cumulus…”
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9
Reorganization of the flagellum scaffolding induces a sperm standstill during fertilization
Published in eLife (13-11-2024)“…Mammalian sperm delve into the female reproductive tract to fertilize the female gamete. The available information about how sperm regulate their motility…”
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10
Role of Ion Channels in the Sperm Acrosome Reaction
Published in Advances in anatomy, embryology and cell biology (01-01-2016)“…The acrosome reaction (AR) is a unique exocytotic process where the acrosome, a single membrane-delimited specialized organelle, overlying the nucleus in the…”
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11
Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood
Published in Proceedings of the National Academy of Sciences - PNAS (14-12-2010)“…There are well-recognized sex differences in many pituitary endocrine axes, usually thought to be generated by gonadal steroid imprinting of the neuroendocrine…”
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12
GnRH-Induced [Ca2+]i-signalling patterns in mouse gonadotrophs recorded from acute pituitary slices in vitro
Published in Neuroendocrinology (01-06-2010)“…In this study we used [Ca(2+)](i) imaging to monitor GnRH-induced intracellular Ca(2+) signalling from dozens of gonadotrophs in mouse male pituitary slices…”
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13
Acute Slices of Mice Testis Seminiferous Tubules Unveil Spontaneous and Synchronous Ca2+ Oscillations in Germ Cell Clusters
Published in Biology of reproduction (01-10-2012)“…Spermatogenic cell differentiation involves changes in the concentration of cytoplasmic Ca(2+) ([Ca(2+)]i); however, very few studies exist on [Ca(2+)]i…”
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14
Are TRP channels involved in sperm development and function?
Published in Cell and tissue research (01-09-2012)“…Spermatozoa must translate information from their environment and the egg to achieve fertilization in sexually reproducing animals. These tasks require…”
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15
Ca²⁺ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways
Published in Proceedings of the National Academy of Sciences - PNAS (12-11-2013)“…Ca ²⁺ ionophore A23187 is known to induce the acrosome reaction of mammalian spermatozoa, but it also quickly immobilizes them. Although mouse spermatozoa were…”
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16
Starvation induces an increase in intracellular calcium and potentiates the progesterone‐induced mouse sperm acrosome reaction
Published in The FASEB journal (01-04-2021)“…We have recently reported two different methodologies that improve sperm functionality. The first method involved transient exposure to the Ca2+ ionophore…”
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17
Seeing is believing: Current methods to observe sperm acrosomal exocytosis in real time
Published in Molecular reproduction and development (01-12-2020)“…Acrosomal exocytosis (AR) is a critical process that sperm need to undergo to fertilize an egg. The evaluation of the presence or absence of the acrosome is…”
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18
Mouse Sperm Membrane Potential Hyperpolarization Is Necessary and Sufficient to Prepare Sperm for the Acrosome Reaction
Published in The Journal of biological chemistry (28-12-2012)“…Mammalian sperm are unable to fertilize the egg immediately after ejaculation; they acquire this capacity during migration in the female reproductive tract…”
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19
Differential role of bovine serum albumin and HCO3- in the regulation of GSK3 alpha during mouse sperm capacitation
Published in Molecular human reproduction (29-02-2024)“…To become fertile, mammalian sperm are required to undergo capacitation in the female tract or in vitro in defined media containing ions (e.g. HCO3 -, Ca2+,…”
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20
Reorganization of the flagellum scaffolding induces a sperm standstill during fertilization
Published in eLife (12-11-2024)“…Mammalian sperm delve into the female reproductive tract to fertilize the female gamete. The available information about how sperm regulate their motility…”
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