Search Results - "Sanchez‐Ruderisch, Hugo"

Tumor suppressor p16INK⁴a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model by Sanchez-Ruderisch, Hugo, Fischer, Christian, Detjen, Katharina M, Welzel, Martina, Wimmel, Anja, Manning, Joachim C, André, Sabine, Gabius, Hans-Joachim

“…The tumor suppressor p16INK⁴a has functions beyond cell-cycle control via cyclin-dependent kinases. A coordinated remodeling of N- and O-glycosylation, and an…”
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Tumor suppressor p16INK4a controls oncogenic K‐Ras function in human pancreatic cancer cells by Rabien, Anja, Sanchez‐Ruderisch, Hugo, Schulz, Petra, Otto, Noreen, Wimmel, Anja, Wiedenmann, Bertram, Detjen, Katharina M.

“…Pancreatic cancer is characterized by oncogenic activation of K‐Ras and inactivation of the cell cycle inhibitor p16INK4a. We previously demonstrated that…”
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Sex- and estrogen-dependent regulation of a miRNA network in the healthy and hypertrophied heart by Queirós, Ana Maria, Eschen, Claudia, Fliegner, Daniela, Kararigas, Georgios, Dworatzek, Elke, Westphal, Christina, Sanchez Ruderisch, Hugo, Regitz-Zagrosek, Vera

“…Abstract Background In pressure overload, profibrotic gene expression and cardiac fibrosis are more pronounced in males than in females. Sex-specific and…”
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Sex-specific regulation of cardiac microRNAs targeting mitochondrial proteins in pressure overload by Sanchez-Ruderisch, Hugo, Queirós, Ana Maria, Fliegner, Daniela, Eschen, Claudia, Kararigas, Georgios, Regitz-Zagrosek, Vera

“…Maladaptive remodeling in pressure overload (PO)-induced left ventricular hypertrophy (LVH) may lead to heart failure. Major sex differences have been reported…”
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Loss of UDP‐N‐acetylglucosamine 2‐epimerase/N‐acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells by Kemmner, Wolfgang, Kessel, Pia, Sanchez‐Ruderisch, Hugo, Möller, Heinz, Hinderlich, Stephan, Schlag, Peter M., Detjen, Katharina

“…ABSTRACT Early invasive growth and metastasis are features of pancreatic cancer that rely on its resistance to anoikis, an apoptosis program activated on loss…”
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Tumor suppressor p16INK4a − modulator of glycomic profile and galectin‐1 expression to increase susceptibility to carbohydrate‐dependent induction of anoikis in pancreatic carcinoma cells by André, Sabine, Sanchez‐Ruderisch, Hugo, Nakagawa, Hiroaki, Buchholz, Malte, Kopitz, Jürgen, Forberich, Pia, Kemmner, Wolfgang, Böck, Corina, Deguchi, Kisaburo, Detjen, Katharia M., Wiedenmann, Bertram, von Knebel Doeberitz, Magnus, Gress, Thomas M., Nishimura, Shin‐Ichiro, Rosewicz, Stefan, Gabius, Hans‐Joachim

“…Expression of the tumor suppressor p16INK4a after stable transfection can restore the susceptibility of epithelial tumor cells to anoikis. This property is…”
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Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model by Sanchez-Ruderisch, Hugo, Fischer, Christian, Detjen, Katharina M, Welzel, Martina, Wimmel, Anja, Manning, Joachim C, André, Sabine, Gabius, Hans-Joachim

“…The tumor suppressor p16(INK4a) has functions beyond cell-cycle control via cyclin-dependent kinases. A coordinated remodeling of N- and O-glycosylation, and…”
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Activin A stimulates vascular endothelial growth factor gene transcription in human hepatocellular carcinoma cells by Wagner, Karola, Peters, Michael, Scholz, Arne, Benckert, Christoph, Ruderisch, Hugo Sanchez, Wiedenmann, Bertram, Rosewicz, Stefan

“…Background & Aims : Up-regulation of vascular endothelial growth factor is known to play a critical role in hepatocellular tumor biology. In an attempt to…”
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Galectin-1 Interacts with the α5β1 Fibronectin Receptor to Restrict Carcinoma Cell Growth via Induction of p21 and p27 by Fischer, Christian, Sanchez-Ruderisch, Hugo, Welzel, Martina, Wiedenmann, Bertram, Sakai, Toshiyuki, André, Sabine, Gabius, Hans-Joachim, Khachigian, Levon, Detjen, Katharina M., Rosewicz, Stefan

“…Surface binding of galectin family members has the potential to link distinct glycan structures to growth regulation. Therefore, we addressed the…”
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Genetic Background Defines the Regulation of Postnatal Cardiac Growth by 17β-Estradiol Through a β-Catenin Mechanism by Kararigas, Georgios, Nguyen, Ba Tiep, Zelarayan, Laura C, Hassenpflug, Maike, Toischer, Karl, Sanchez-Ruderisch, Hugo, Hasenfuss, Gerd, Bergmann, Martin W, Jarry, Hubertus, Regitz-Zagrosek, Vera

“…Estrogen regulates several biological processes in health and disease. Specifically, estrogen exerts antihypertrophic effects in the diseased heart. However,…”
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CardioNet: a human metabolic network suited for the study of cardiomyocyte metabolism by Karlstädt, Anja, Fliegner, Daniela, Kararigas, Georgios, Ruderisch, Hugo Sanchez, Regitz-Zagrosek, Vera, Holzhütter, Hermann-Georg

“…Availability of oxygen and nutrients in the coronary circulation is a crucial determinant of cardiac performance. Nutrient composition of coronary blood may…”
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Galectin-1 Interacts with the alpha 5 beta 1 Fibronectin Receptor to Restrict Carcinoma Cell Growth via Induction of p21 and p27 by Fischer, Christian, Sanchez-Ruderisch, Hugo, Welzel, Martina, Wiedenmann, Bertram, Sakai, Toshiyuki, Andre, Sabine, Gabius, Hans-Joachim, Khachigian, Levon, Detjen, Katharina M, Rosewicz, Stefan

“…Surface binding of galectin family members has the potential to link distinct glycan structures to growth regulation. Therefore, we addressed the…”
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Abstract 079: Estrogen Receptor beta Regulation Of miRNA Expression In The Heart - A Hint For Sex Differences In Hypertrophy by Queirós, Ana, Eschen, Claudia, Fliegner, Daniela, Regitz-Zagrosek, Vera, Sanchez Ruderisch, Hugo

“…Abstract only Sex differences (SD) in cardiovascular diseases are described and have been attributed to the effects of sex hormones, such as estrogen (E2). Our…”
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Abstract 055: β-Catenin Mediates an Interplay between Genetic Background and Growth-Regulating Effects of Estrogen in the Healthy Heart by Kararigas, Georgios, Nguyen, Ba Tiep, Zelarayan, Laura C, Hassenpflug, Maike, Toischer, Karl, Sanchez-Ruderisch, Hugo, Hasenfuss, Gerd, Bergmann, Martin W, Jarry, Hubertus, Regitz-Zagrosek, Vera

“…Abstract only In diseased hearts, estrogen (E2) has been shown to exert anti-hypertrophic actions. Little is known about the role of E2 in the healthy heart…”
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Tumor suppressor p16 INK4a controls oncogenic K‐Ras function in human pancreatic cancer cells by Rabien, Anja, Sanchez‐Ruderisch, Hugo, Schulz, Petra, Otto, Noreen, Wimmel, Anja, Wiedenmann, Bertram, Detjen, Katharina M.

“…Pancreatic cancer is characterized by oncogenic activation of K‐Ras and inactivation of the cell cycle inhibitor p16 INK4a . We previously demonstrated that…”
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Galectin-1 sensitizes carcinoma cells to anoikis via the α5β1 fibronectin receptor by Detjen, Katharina M., Sanchez-Ruderisch, Hugo, Welzel, Martina, André, Sabine, Fischer, Christian, Gabius, Hans-Joachim, Rosewicz, Stefan

“…Anoikis resistance is a hallmark of transformed epithelial cells. Here, we show that treatment of anoikis-resistant carcinoma cell lines with the endogenous…”
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L-Ascorbic Acid Increases NFκB Binding Activity in UVA-Irradiated HaCaT Keratinocytes by Tebbe, Beate, Schwarz, Constanze, Ruderisch, Hugo Sánchez, Treudler, Regina, Orfanos, Constantin E.

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Tumor suppressor p16 super(INK4a) - modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells by Andre, Sabine, Sanchez-Ruderisch, Hugo, Nakagawa, Hiroaki, Buchholz, Malte, Kopitz, Jurgen, berich, Pia, Kemmner, Wolfgang, Bock, Corina, Deguchi, Kisaburo, Detjen, Katharia M, Wiedenmann, Bertram, von Knebel Doeberitz, Magnus, Gress, Thomas M, Nishimura, Shin-Ichiro, Rosewicz, Stefan, Gabius, Hans-Joachim

“…Expression of the tumor suppressor p16 super(INK4a) after stable transfection can restore the susceptibility of epithelial tumor cells to anoikis. This…”
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Tumor suppressor p16 INK4a  − modulator of glycomic profile and galectin‐1 expression to increase susceptibility to carbohydrate‐dependent induction of anoikis in pancreatic carcinoma cells by André, Sabine, Sanchez‐Ruderisch, Hugo, Nakagawa, Hiroaki, Buchholz, Malte, Kopitz, Jürgen, Forberich, Pia, Kemmner, Wolfgang, Böck, Corina, Deguchi, Kisaburo, Detjen, Katharia M., Wiedenmann, Bertram, von Knebel Doeberitz, Magnus, Gress, Thomas M., Nishimura, Shin‐Ichiro, Rosewicz, Stefan, Gabius, Hans‐Joachim

“…Expression of the tumor suppressor p16 INK4a after stable transfection can restore the susceptibility of epithelial tumor cells to anoikis. This property is…”
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Galectin-1 interacts with the {alpha}5{beta}1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p27 by Fischer, Christian, Sanchez-Ruderisch, Hugo, Welzel, Martina, Wiedenmann, Bertram, Sakai, Toshiyuki, André, Sabine, Gabius, Hans-Joachim, Khachigian, Levon, Detjen, Katharina M, Rosewicz, Stefan

“…Surface binding of galectin family members has the potential to link distinct glycan structures to growth regulation. Therefore, we addressed the…”
Get full text