Search Results - "Sanchez, Julie"
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Mechanisms of Regulation of the Chemokine-Receptor Network
Published in International journal of molecular sciences (07-02-2017)“…The interactions of chemokines with their G protein-coupled receptors promote the migration of leukocytes during normal immune function and as a key aspect of…”
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Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates
Published in Molecular therapy (07-08-2019)“…Site-specific correction of a point mutation causing a monogenic disease in autologous hematopoietic stem and progenitor cells (HSPCs) can be used as a…”
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Sulfation of the Human Cytomegalovirus Protein UL22A Enhances Binding to the Chemokine RANTES
Published in Angewandte Chemie International Edition (10-07-2017)“…UL22A is an 83 amino acid chemokine‐binding protein produced by human cytomegalovirus that likely assists the virus in dampening the host antiviral response…”
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Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1
Published in International journal of molecular sciences (15-05-2019)“…Leukocyte migration, a hallmark of the inflammatory response, is stimulated by the interactions between chemokines, which are expressed in injured or infected…”
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Key determinants of selective binding and activation by the monocyte chemoattractant proteins at the chemokine receptor CCR2
Published in Science signaling (23-05-2017)“…Chemokines and their receptors collectively orchestrate the trafficking of leukocytes in normal immune function and inflammatory diseases. Different chemokines…”
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Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism
Published in eLife (27-01-2020)“…By analyzing and simulating inactive conformations of the highly homologous dopamine D and D receptors (D R and D R), we find that eticlopride binds D R in a…”
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Global and Local Manipulation of DNA Repair Mechanisms to Alter Site-Specific Gene Editing Outcomes in Hematopoietic Stem Cells
Published in Frontiers in genome editing (10-12-2020)“…Monogenic disorders of the blood system have the potential to be treated by autologous stem cell transplantation of ex vivo genetically modified hematopoietic…”
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IMPACT OF AGE AND SEX ON ALCOHOL DRINKING BEHAVIOUR: ROLE OF ETHANOL METABOLISM
Published in IBRO neuroscience reports (01-10-2023)Get full text
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EFFECT OF MICROGLIAL ACTIVATION ON NEURONAL MU-OPIOID RECEPTOR EXPRESSION AND SIGNALLING
Published in IBRO neuroscience reports (01-10-2023)Get full text
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10
Obstructed hemivagina with ipsilateral renal agenesis (OHVIRA) syndrome with imperforate anus
Published in Journal of pediatric surgery case reports (01-09-2016)“…Abstract OHVIRA syndrome (Obstructed hemivagina with ipsilateral renal agenesis) is a rare Mullerian duct anomaly that results in uterine didelphys, obstructed…”
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Traumatic presentation of a solid pancreatic pseudopapillary neoplasm in a 7 year old girl
Published in Journal of pediatric surgery case reports (01-06-2015)“…Abstract Solid pseudopapillary neoplasms of the pancreas are rare tumors that present in adolescence after having grown to a large size. We present the case of…”
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Arrestin-centred interactions at the membrane and their conformational determinants
Published in British journal of pharmacology (13-03-2024)“…More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein-coupled receptor (GPCR)…”
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Understanding the role of sorption and biodegradation in the removal of organic micropollutants by membrane aerated biofilm reactor (MABR) with different biofilm thickness
Published in Water research (Oxford) (01-06-2023)“…•Biodegradation is the main mechanism driving the removal of OMPs via MABR.•Heterotrophic activity dominates OMPs biodegradation at all biofilm thickness.•MABR…”
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14
Pseudoaneurysm associated with multiple osteochondromatosis
Published in Journal of pediatric surgery (01-07-2005)“…The authors present a case of a 12-year-old boy with a known family history of multiple hereditary exostoses who presented with knee swelling. Physical…”
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15
Biomass generation and heterologous isoprenoid milking from engineered microalgae grown in anaerobic membrane bioreactor effluent
Published in Water research (Oxford) (01-02-2023)“…•Engineered Chlamydomonas can grow directly in AnMBR effluent.•Algal strain grew in modeled environmental conditions of the central Red Sea coast.•Algae…”
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Traumatic Head Injuries Caused by Ceiling Fans Among Children Treated in US Emergency Departments
Published in Pediatrics (Evanston) (01-09-2023)Get full text
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A Predictive Model to Identify Skilled Nursing Facility Residents for Pharmacist Intervention
Published in The Consultant pharmacist (01-09-2018)“…Objective Develop a predictive model to identify patients in a skilled nursing facility (SNF) who require a clinical pharmacist intervention. Design…”
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Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D3 (D3R) and μ-Opioid (MOR) Receptors Ligands as Potentially Safer Analgesics
Published in Journal of medicinal chemistry (19-07-2023)“…A new generation of dual-target mu opioid receptor (MOR) agonist/dopamine D 3 receptor (D 3 R) antagonist/partial agonists with optimized physicochemical…”
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Traumatic Head Injuries from Ceiling Fans at a Pediatric Level I Trauma Center in the United States
Published in Pediatric neurosurgery (01-02-2024)“…Several studies describe traumatic head injuries caused by ceiling fans in Australia, the Middle East, and Malaysia. Some injuries required neurosurgical…”
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Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D3 (D3R) and μ‑Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics
Published in Journal of medicinal chemistry (10-08-2023)“…A new generation of dual-target μ opioid receptor (MOR) agonist/dopamine D3 receptor (D3R) antagonist/partial agonists with optimized physicochemical…”
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