Search Results - "Sanada, Yu"

Correlation between the expression of LAT1 in cancer cells and the potential efficacy of boron neutron capture therapy by Watanabe, Tsubasa, Sanada, Yu, Hattori, Yoshihide, Suzuki, Minoru

“…Boron neutron capture therapy (BNCT) is a binary cancer therapy that involves boron administration and neutron irradiation. The nuclear reaction caused by the…”
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Design, Synthesis, and Evaluation of Lipopeptide Conjugates of Mercaptoundecahydrododecaborate for Boron Neutron Capture Therapy by Isono, Aoi, Tsuji, Mieko, Sanada, Yu, Matsushita, Akari, Masunaga, Shinichiro, Hirayama, Tasuku, Nagasawa, Hideko

“…We developed new 10B carriers for boron neutron capture therapy (BNCT) that can effectively transport and accumulate boron clusters into cells. These carriers…”
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Tumor-targeting hyaluronic acid/fluorescent carborane complex for boron neutron capture therapy by Yamana, Keita, Kawasaki, Riku, Sanada, Yu, Tabata, Anri, Bando, Kaori, Yoshikawa, Kouhei, Azuma, Hideki, Sakurai, Yoshinori, Masunaga, Shin-ichiro, Suzuki, Minoru, Sugikawa, Kouta, Nagasaki, Takeshi, Ikeda, Atsushi

“…In cancer therapeutics, boron neutron capture therapy (BNCT) requires a platform for selective and efficient 10B delivery into tumor tissues for a successful…”
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Phospholipid‐Coated Boronic Oxide Nanoparticles as Boron Agents for Boron Neutron Capture Therapy by Kawasaki, Riku, Hirano, Hidetoshi, Yamana, Keita, Oshige, Ayano, Nishimura, Kotaro, Kono, Nanami, Sanada, Yu, Bando, Kaori, Tabata, Anri, Yasukawa, Naoki, Azuma, Hideki, Takata, Takushi, Sakurai, Yoshinori, Tanaka, Hiroki, Suzuki, Minoru, Tarutani, Naoki, Katagiri, Kiyofumi, Nagasaki, Takeshi, Ikeda, Atsushi

“…Minimally invasive boron neutron capture therapy (BNCT) is an elegant approach for cancer treatment. The highly selective and efficient deliverability of boron…”
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The impact of TP53 status of tumor cells including the type and the concentration of administered 10B delivery agents on compound biological effectiveness in boron neutron capture therapy by Masunaga, Shin-ichiro, Sanada, Yu, Takata, Takushi, Tanaka, Hiroki, Sakurai, Yoshinori, Suzuki, Minoru, Kirihata, Mitsunori, Ono, Koji

“…Abstract Human head and neck squamous cell carcinoma cells transfected with mutant TP53 (SAS/mp53) or neo vector (SAS/neo) were inoculated subcutaneously into…”
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An attempt to improve the therapeutic effect of boron neutron capture therapy using commonly employed 10B-carriers based on analytical studies on the correlation among quiescent tumor cell characteristics, tumor heterogeneity and cancer stemness by Masunaga, Shin-Ichiro, Sanada, Yu, Tano, Keizo, Sakurai, Yoshinori, Tanaka, Hiroki, Takata, Takushi, Suzuki, Minoru, Ono, Koji

“…Based on our previously published reports concerning the response of quiescent (Q) tumor cell populations to boron neutron capture therapy (BNCT), the…”
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Proteomic Characterization of SAS Cell-Derived Extracellular Vesicles in Relation to Both BPA and Neutron Irradiation Doses by Perico, Davide, Tong, Ying, Chen, Lichao, Imamichi, Shoji, Sanada, Yu, Ishiai, Masamichi, Suzuki, Minoru, Masutani, Mitsuko, Mauri, Pierluigi

“…Boron neutron capture therapy (BNCT) is a selective radiotherapy based on nuclear reaction that occurs when B atoms accumulated in cancer cells are irradiated…”
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Extracellular Release of HMGB1 as an Early Potential Biomarker for the Therapeutic Response in a Xenograft Model of Boron Neutron Capture Therapy by Imamichi, Shoji, Chen, Lichao, Ito, Tasuku, Tong, Ying, Onodera, Takae, Sasaki, Yuka, Nakamura, Satoshi, Mauri, PierLuigi, Sanada, Yu, Igaki, Hiroshi, Murakami, Yasufumi, Suzuki, Minoru, Itami, Jun, Masunaga, Shinichiro, Masutani, Mitsuko

“…Boron neutron capture therapy (BNCT) is a non-invasive therapeutic technique for treating malignant tumors, however, methods to evaluate its therapeutic…”
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Correction: Imamichi et al. Extracellular Release of HMGB1 as an Early Potential Biomarker for the Therapeutic Response in a Xenograft Model of Boron Neutron Capture Therapy. Biology 2022, 11, 420 by Imamichi, Shoji, Chen, Lichao, Ito, Tasuku, Tong, Ying, Onodera, Takae, Sasaki, Yuka, Nakamura, Satoshi, Mauri, PierLuigi, Sanada, Yu, Igaki, Hiroshi, Murakami, Yasufumi, Suzuki, Minoru, Itami, Jun, Masunaga, Shinichiro, Masutani, Mitsuko

“…In the original publication [...]…”
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Effect of a change in reactor power on response of murine solid tumors in vivo, referring to impact on quiescent tumor cell population by Masunaga, Shin-ichiro, Sakurai, Yoshinori, Tanaka, Hiroki, Takata, Takushi, Suzuki, Minoru, Sanada, Yu, Tano, Keizo, Maruhashi, Akira, Ono, Koji

“…Purpose: To examine the effect of a change in reactor power on the response of solid tumors, referring to impact on quiescent (Q) tumor cell population…”
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Effect of Tirapazamine, Metformin or Mild Hyperthermia on Recovery From Radiation-Induced Damage in Pimonidazole-Unlabeled Quiescent Tumor Cells by Masunaga, Shin-ichiro, Tano, Keizo, Sanada, Yu, Sakurai, Yoshinori, Tanaka, Hiroki, Suzuki, Minoru, Kondo, Natsuko, Watanabe, Tsubasa, Takata, Takushi, Maruhashi, Akira, Ono, Koji

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Systems Biology Approach to Investigate Biomarkers, Boron-10 Carriers, and Mechanisms Useful for Improving Boron Neutron Capture Therapy by Perico, Davide, Di Silvestre, Dario, Imamichi, Shoji, Sanada, Yu, Masutani, Mitsuko, Mauri, Pier Luigi

“…Systems biology approach, carried out with high-throughput omics technologies, has become a fundamental aspect of the study of complex diseases like cancer. It…”
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HIF-1α affects sensitivity of murine squamous cell carcinoma to boron neutron capture therapy with BPA by Sanada, Yu, Takata, Takushi, Tanaka, Hiroki, Sakurai, Yoshinori, Watanabe, Tsubasa, Suzuki, Minoru, Masunaga, Shin-ichiro

“…Purpose To examine whether hypoxia and Hif-1α affect sensitivity of murine squamous cell carcinoma cells to boron neutron capture therapy (BNCT). Materials and…”
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HER‐2‐Targeted Boron Neutron Capture Therapy with Carborane‐integrated Immunoliposomes Prepared via an Exchanging Reaction by Kawasaki, Riku, Oshige, Ayano, Yamana, Keita, Hirano, Hidetoshi, Nishimura, Kotaro, Miura, Yamato, Yorioka, Ryuji, Sanada, Yu, Bando, Kaori, Tabata, Anri, Yasuhara, Kazuma, Miyazaki, Yusuke, Shinoda, Wataru, Nishimura, Tomoki, Azuma, Hideki, Takata, Takushi, Sakurai, Yoshinori, Tanaka, Hiroki, Suzuki, Minoru, Nagasaki, Takeshi, Ikeda, Atsushi

“…Boron neutron capture therapy (BNCT) is a promising modality for cancer treatment because of its minimal invasiveness. To maximize the therapeutic benefits of…”
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The impact of TP53 status of tumor cells including the type and the concentration of administered [.sup.10]B delivery agents on compound biological effectiveness in boron neutron capture therapy by Masunaga, Shin-Ichiro, Sanada, Yu, Takata, Takushi, Tanaka, Hiroki, Sakurai, Yoshinori, Suzuki, Minoru, Kirihata, Mitsunori, Ono, Koji

“…Human head and neck squamous cell carcinoma cells transfected with mutant TP53 (SAS/mp53) or neo vector (SAS/neo) were inoculated subcutaneously into left hind…”
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Carborane bearing pullulan nanogel-boron oxide nanoparticle hybrid for boron neutron capture therapy by Kawasaki, Riku, Hirano, Hidetoshi, Yamana, Keita, Isozaki, Hinata, Kawamura, Shogo, Sanada, Yu, Bando, Kaori, Tabata, Anri, Yoshikawa, Kouhei, Azuma, Hideki, Takata, Takushi, Tanaka, Hiroki, Sakurai, Yoshinori, Suzuki, Minoru, Tarutani, Naoki, Katagiri, Kiyofumi, Sawada, Shin-ichi, Sasaki, Yoshihiro, Akiyoshi, Kazunari, Nagasaki, Takeshi, Ikeda, Atsushi

“…Boron neutron capture therapy shows is a promising approach to cancer therapy, but the delivery of effective boron agents is challenging. To address the…”
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Extracellular Vesicles Comprising Carborane Prepared by a Host Exchanging Reaction as a Boron Carrier for Boron Neutron Capture Therapy by Kawasaki, Riku, Oshige, Ayano, Kono, Nanami, Yamana, Keita, Hirano, Hidetoshi, Miura, Yamato, Yorioka, Ryuji, Bando, Kaori, Tabata, Anri, Yasukawa, Naoki, Sadakane, Masahiro, Sanada, Yu, Suzuki, Minoru, Takata, Takushi, Sakurai, Yoshinori, Tanaka, Hiroki, Yimiti, Dilimulati, Miyaki, Shigeru, Adachi, Nobuo, Mizuta, Ryosuke, Sasaki, Yoshihiro, Akiyoshi, Kazunari, Hattori, Yoshihide, Kirihata, Mitsunori, Nagasaki, Takeshi, Ikeda, Atsushi

“…With their low immunogenicity and excellent deliverability, extracellular vesicles (EVs) are promising platforms for drug delivery systems. In this study,…”
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An attempt to improve the therapeutic effect of boron neutron capture therapy using commonly employed [.sup.10]B-carriers based on analytical studies on the correlation among quiescent tumor cell characteristics, tumor heterogeneity and cancer stemness by Masunaga, Shin-ichiro, Sanada, Yu, Tano, Keizo, Sakurai, Yoshinori, Tanaka, Hiroki, Takata, Takushi, Suzuki, Minoru, Ono, Koji

“…Based on our previously published reports concerning the response of quiescent (Q) tumor cell populations to boron neutron capture therapy (BNCT), the…”
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Disruption of Hif-1α enhances cytotoxic effects of metformin in murine squamous cell carcinoma by Sanada, Yu, Sasanuma, Hiroyuki, Takeda, Shunichi, Tano, Keizo, Masunaga, Shin-ichiro

“…Purpose: In the present study, we investigated whether the disruption of the Hif-1α gene affects the sensitivity of SCC VII cells to metformin and also if…”
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Comparison of the pharmacokinetics between L-BPA and L-FBPA using the same administration dose and protocol: a validation study for the theranostic approach using [ 18 F]-L-FBPA positron emission tomography in boron neutron capture therapy by Watanabe, Tsubasa, Hattori, Yoshihide, Ohta, Youichiro, Ishimura, Miki, Nakagawa, Yosuke, Sanada, Yu, Tanaka, Hiroki, Fukutani, Satoshi, Masunaga, Shin-Ichiro, Hiraoka, Masahiro, Ono, Koji, Suzuki, Minoru, Kirihata, Mitsunori

“…Boron neutron capture therapy (BNCT) is a cellular-level particle radiation therapy that combines the selective delivery of boron compounds to tumour tissue…”
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