Search Results - "Sanada, Kamon"

Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells by Kurabayashi, Nobuhiro, Sanada, Kamon

“…Down's syndrome (DS), a major genetic cause of mental retardation, arises from triplication of genes on human chromosome 21. Here we show that DYRK1A…”
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Triple play of DYRK1A kinase in cortical progenitor cells of Trisomy 21 by Kurabayashi, Nobuhiro, Nguyen, Minh Dang, Sanada, Kamon

“…•Dyrk1a is a gene located on human chromosome 21.•DYRK1A plays the triple roles in the brain development of Down syndrome mouse models.•Increased dosage of…”
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G Protein βγ Subunits and AGS3 Control Spindle Orientation and Asymmetric Cell Fate of Cerebral Cortical Progenitors by Sanada, Kamon, Tsai, Li-Huei

“…Neurons in the developing mammalian brain are generated from progenitor cells in the proliferative ventricular zone, and control of progenitor division is…”
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AMP-activated protein kinase regulates cytoplasmic dynein behavior and contributes to neuronal migration in the developing neocortex by Naito, Yasuki, Asada, Naoyuki, Nguyen, Minh Dang, Sanada, Kamon

“…The microtubule motor cytoplasmic dynein contributes to radial migration of newborn pyramidal neurons in the developing neocortex. Here, we show that…”
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DYRK1A and Glycogen Synthase Kinase 3β, a Dual-Kinase Mechanism Directing Proteasomal Degradation of CRY2 for Circadian Timekeeping by Kurabayashi, Nobuhiro, Hirota, Tsuyoshi, Sakai, Mihoko, Sanada, Kamon, Fukada, Yoshitaka

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The LPA-LPA4 axis is required for establishment of bipolar morphology and radial migration of newborn cortical neurons by Kurabayashi, Nobuhiro, Tanaka, Aiki, Nguyen, Minh Dang, Sanada, Kamon

“…Newborn neurons in the developing neocortex undergo radial migration, a process that is coupled with their precise passage from multipolar to bipolar shape…”
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The G protein-coupled receptor GPRC5B contributes to neurogenesis in the developing mouse neocortex by Kurabayashi, Nobuhiro, Nguyen, Minh Dang, Sanada, Kamon

“…Neural progenitor cells in the developing brain give rise to neurons and glia. Multiple extrinsic signalling molecules and their cognate membrane receptors…”
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LKB1 Regulates Neuronal Migration and Neuronal Differentiation in the Developing Neocortex through Centrosomal Positioning by Asada, Naoyuki, Sanada, Kamon, Fukada, Yoshitaka

“…The cerebral cortex is formed through the coordination of highly organized cellular processes such as neuronal migration and neuronal maturation. Polarity…”
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The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway by Takeo, Yutaka, Kurabayashi, Nobuhiro, Nguyen, Minh Dang, Sanada, Kamon

“…The ability of radial glial progenitors (RGPs) to generate cortical neurons is determined by local extracellular factors and signaling pathways intrinsic to…”
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Cep120 and TACCs Control Interkinetic Nuclear Migration and the Neural Progenitor Pool by Xie, Zhigang, Moy, Lily Y., Sanada, Kamon, Zhou, Ying, Buchman, Joshua J., Tsai, Li-Huei

“…Centrosome- and microtubule-associated proteins have been shown to be important for maintaining the neural progenitor pool during neocortical development by…”
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Increased anxiety in offspring reared by circadian Clock mutant mice by Koizumi, Hiroko, Kurabayashi, Nobuhiro, Watanabe, Yuto, Sanada, Kamon

“…The maternal care that offspring receive from their mothers early in life influences the offspring's development of emotional behavior in adulthood. Here we…”
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Time-of-day-dependent enhancement of adult neurogenesis in the hippocampus by Tamai, So-ichi, Sanada, Kamon, Fukada, Yoshitaka

“…Adult neurogenesis occurs in specific regions of the mammalian brain such as the dentate gyrus of the hippocampus. In the neurogenic region, neural progenitor…”
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Disabled-1-Regulated Adhesion of Migrating Neurons to Radial Glial Fiber Contributes to Neuronal Positioning during Early Corticogenesis by Sanada, Kamon, Gupta, Amitabh, Tsai, Li-Huei

“…Disabled-1 regulates laminar organization in the developing mammalian brain. Although mutation of the disabled-1 gene in scrambler mice results in…”
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Serine 732 Phosphorylation of FAK by Cdk5 Is Important for Microtubule Organization, Nuclear Movement, and Neuronal Migration by Xie, Zhigang, Sanada, Kamon, Samuels, Benjamin Adam, Shih, Heather, Tsai, Li-Huei

“…The serine/threonine kinase Cdk5 plays an essential role in neuronal positioning during corticogenesis, but the underlying mechanisms are unknown. In…”
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Phosphorylation of Targeting Protein for Xenopus Kinesin-like Protein 2 (TPX2) at Threonine 72 in Spindle Assembly by Shim, Su Yeon, de Castro, Ignacio Perez, Neumayer, Gernot, Wang, Jian, Park, Sang Ki, Sanada, Kamon, Nguyen, Minh Dang

“…The human ortholog of the targeting protein for Xenopus kinesin-like protein 2 (TPX2) is a cytoskeletal protein that plays a major role in spindle assembly and…”
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Mitogen-activated Protein Kinase Phosphorylates and Negatively Regulates Basic Helix-Loop-Helix-PAS Transcription Factor BMAL1 by Sanada, Kamon, Okano, Toshiyuki, Fukada, Yoshitaka

“…In vertebrates, mitogen-activated protein kinase (MAPK) exhibits circadian activation in several clock structures and likely participates in the timekeeping…”
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Protein 600 Is a Microtubule/Endoplasmic Reticulum-Associated Protein in CNS Neurons by Shim, Su Yeon, Wang, Jian, Asada, Naoyuki, Neumayer, Gernot, Tran, Hong Chi, Ishiguro, Kei-ichiro, Sanada, Kamon, Nakatani, Yoshihiro, Nguyen, Minh Dang

“…There is an increasing body of literature pointing to cytoskeletal proteins as spatial organizers and interactors of organelles. In this study, we identified…”
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Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migration by Tsai, Li-Huei, Gupta, Amitabh, Sanada, Kamon, Miyamoto, David T, Rovelstad, Susan, Nadarajah, Bagirathy, Pearlman, Alan L, Brunstrom, Jan

“…Several genes essential for neocortical layering have been identified in recent years, but their precise roles in this process remain to be elucidated. Mice…”
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Serine phosphorylation of mCRY1 and mCRY2 by mitogen‐activated protein kinase by Sanada, Kamon, Harada, Yuko, Sakai, Mihoko, Todo, Takeshi, Fukada, Yoshitaka

“…The circadian oscillator is composed of a transcription/translation‐based autoregulatory feedback loop in which Cryptochromes and Periods function as negative…”
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p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex by Belzil, Camille, Asada, Naoyuki, Ishiguro, Kei-Ichiro, Nakaya, Takeo, Parsons, Kari, Pendolino, Valentina, Neumayer, Gernot, Mapelli, Marina, Nakatani, Yoshihiro, Sanada, Kamon, Nguyen, Minh Dang

“…Apical neural progenitors (aNPs) drive neurogenesis by means of a program consisting of self-proliferative and neurogenic divisions. The balance between these…”
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