Search Results - "Sana, Ilenia"
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Role of NFAT in Chronic Lymphocytic Leukemia and Other B-Cell Malignancies
Published in Frontiers in oncology (01-04-2021)“…In recent years significant progress has been made in the clinical management of chronic lymphocytic leukemia (CLL) as well as other B-cell malignancies;…”
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Disrupting pro-survival and inflammatory pathways with dimethyl fumarate sensitizes chronic lymphocytic leukemia to cell death
Published in Cell death & disease (18-03-2024)“…Microenvironmental signals strongly influence chronic lymphocytic leukemia (CLL) cells through the activation of distinct membrane receptors, such as B-cell…”
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Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines
Published in FEBS open bio (01-12-2023)“…Chronic lymphocytic leukemia (CLL) is a prototypic neoplasia in which malignant cells strongly depend on microenvironmental stimulations in the lymphoid…”
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SIGIRR Downregulation and Interleukin-1 Signaling Intrinsic to Renal Cell Carcinoma
Published in Frontiers in oncology (22-06-2022)“…Renal cell carcinoma is highly inflamed, and tumor cells are embedded into a microenvironment enriched with IL1. While inflammatory pathways are well…”
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Toll-like receptor 9 stimulation can induce IκBζ expression and IgM secretion in chronic lymphocytic leukemia cells
Published in Haematologica (Roma) (01-11-2017)“…Chronic lymphocytic leukemia cells strongly depend on external stimuli for their survival. Both antigen receptor and co-stimulatory receptors, including…”
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Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia
Published in European journal of immunology (01-10-2023)“…Chronic lymphocytic leukemia (CLL) co‐evolves with its own microenvironment where inflammatory stimuli including toll‐like receptors (TLR) signaling can…”
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Interleukin‐1 receptor‐associated kinase 4 inhibitor interrupts toll‐like receptor signalling and sensitizes chronic lymphocytic leukaemia cells to apoptosis
Published in British journal of haematology (01-05-2020)“…Summary Chronic lymphocytic leukaemia (CLL) cells are strongly influenced by microenvironmental signals through the activation of distinct membrane receptors…”
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Virtual unfolding of light sheet fluorescence microscopy dataset for quantitative analysis of the mouse intestine
Published in Journal of biomedical optics (31-05-2016)“…Light sheet fluorescence microscopy has proven to be a powerful tool to image fixed and chemically cleared samples, providing in depth and high resolution…”
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Characterization of a long isoform of IL-1R8 (TIR8/SIGIRR)
Published in European cytokine network (01-06-2017)“…IL-1R8, also known as SIGIRR or TIR8, is a trans-membrane protein belonging to the IL-1 receptor family. The human gene includes ten exons, and alternative…”
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