Search Results - "San Millán, Iñigo"

The Key Role of Mitochondrial Function in Health and Disease by San-Millán, Iñigo

“…The role of mitochondrial function in health and disease has become increasingly recognized, particularly in the last two decades. Mitochondrial dysfunction as…”
Get full text

Assessment of Metabolic Flexibility by Means of Measuring Blood Lactate, Fat, and Carbohydrate Oxidation Responses to Exercise in Professional Endurance Athletes and Less-Fit Individuals by San-Millán, Iñigo, Brooks, George A.

“…Background Increased muscle mitochondrial mass is characteristic of elite professional endurance athletes (PAs), whereas increased blood lactate levels…”
Get full text

Exercise management in type 1 diabetes: a consensus statement by Riddell, Michael C, Prof, Gallen, Ian W, FRCP, Smart, Carmel E, PhD, Taplin, Craig E, FRACP, Adolfsson, Peter, MD, Lumb, Alistair N, MRCP, Kowalski, Aaron, PhD, Rabasa-Lhoret, Remi, Prof, McCrimmon, Rory J, Prof, Hume, Carin, MSc, Annan, Francesca, MSc, Fournier, Paul A, PhD, Graham, Claudia, PhD, Bode, Bruce, MD, Galassetti, Pietro, Prof, Jones, Timothy W, Prof, Millán, Iñigo San, PhD, Heise, Tim, MD, Peters, Anne L, MD, Petz, Andreas, BEd, Laffel, Lori M, MD

“…Summary Type 1 diabetes is a challenging condition to manage for various physiological and behavioural reasons. Regular exercise is important, but management…”
Get full text

Is Lactate an Oncometabolite? Evidence Supporting a Role for Lactate in the Regulation of Transcriptional Activity of Cancer-Related Genes in MCF7 Breast Cancer Cells by San-Millán, Iñigo, Julian, Colleen G, Matarazzo, Christopher, Martinez, Janel, Brooks, George A

“…Lactate is a ubiquitous molecule in cancer. In this exploratory study, our aim was to test the hypothesis that lactate could function as an oncometabolite by…”
Get full text

Metabolomics of Endurance Capacity in World Tour Professional Cyclists by San-Millán, Iñigo, Stefanoni, Davide, Martinez, Janel L, Hansen, Kirk C, D'Alessandro, Angelo, Nemkov, Travis

“…The study of elite athletes provides a unique opportunity to define the upper limits of human physiology and performance. Across a variety of sports, these…”
Get full text

Indirect Assessment of Skeletal Muscle Glycogen Content in Professional Soccer Players before and after a Match through a Non-Invasive Ultrasound Technology by San-Millán, Iñigo, Hill, John C, Calleja-González, Julio

“…Skeletal muscle glycogen (SMG) stores in highly glycolytic activities regulate muscle contraction by controlling calcium release and uptake from sarcoplasmic…”
Get full text

Validation of musculoskeletal ultrasound to assess and quantify muscle glycogen content. A novel approach by Hill, John C, Millán, Iñigo San

“…Glycogen storage is essential for exercise performance. The ability to assess muscle glycogen levels should be an important advantage for performance. However,…”
Get more information

Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect by San-Millán, Iñigo, Brooks, George A

“…Herein, we use lessons learned in exercise physiology and metabolism to propose that augmented lactate production ('lactagenesis'), initiated by gene…”
Get full text

Reply to Comment On: “Indirect Assessment of Skeletal Muscle Glycogen Content in Professional Soccer Players before and after a Match through a Non-Invasive Ultrasound Technology Nutrients 2020, 12(4), 971” by San-Millán, Iñigo, Hill, John, Calleja-González, Julio

“…We would like to thank Professor Niels Ørtenblad et al [...]…”
Get full text

Objective assessment of metabolism and guidance of ICU rehabilitation with cardiopulmonary exercise testing by Whittle, John, San-Millán, Iñigo

“…Addressing the reduced quality of life that affects ICU survivors is the most pressing challenge in critical care medicine. In order to meet this challenge, we…”
Get full text

Authors’ Reply to Monferrer-Marín J, et al.: Assessment of Metabolic Flexibility by Means of Measuring Blood Lactate, Fat, and Carbohydrate Oxidation Responses to Exercise in Professional Endurance Athletes and Less-Fit Individuals by San-Millán, Iñigo, Brooks, George A.

“…[...]we agree with Monferrer-Marín et al. that it may be difficult to know the absolute exercise power outputs we used in conducting our studies. [...]we have…”
Get full text

Metabolic Signatures of Performance in Elite World Tour Professional Male Cyclists by Nemkov, Travis, Cendali, Francesca, Stefanoni, Davide, Martinez, Janel L., Hansen, Kirk C., San-Millán, Iñigo, D’Alessandro, Angelo

“…Background and Objective Metabolomics studies of recreational and elite athletes have been so far limited to venipuncture-dependent blood sample collection in…”
Get full text

Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (PASC) by Guntur, Vamsi P, Nemkov, Travis, de Boer, Esther, Mohning, Michael P, Baraghoshi, David, Cendali, Francesca I, San-Millán, Inigo, Petrache, Irina, D'Alessandro, Angelo

“…Exercise intolerance is a major manifestation of post-acute sequelae of severe acute respiratory syndrome coronavirus infection (PASC, or "long-COVID")…”
Get full text

A Five-Week Periodized Carbohydrate Diet Does Not Improve Maximal Lactate Steady-State Exercise Capacity and Substrate Oxidation in Well-Trained Cyclists compared to a High-Carbohydrate Diet by Prieto-Bellver, Gorka, Diaz-Lara, Javier, Bishop, David J, Fernández-Sáez, José, Abián-Vicén, Javier, San-Millan, Iñigo, Santos-Concejero, Jordan

“…There is a growing interest in studies involving carbohydrate (CHO) manipulation and subsequent adaptations to endurance training. This study aimed to analyze…”
Get full text

Serum creatine kinase elevations in ultramarathon runners at high altitude by Magrini, Danielle, Khodaee, Morteza, San-Millán, Iñigo, Hew-Butler, Tamara, Provance, Aaron J

“…Creatine kinase (CK) is a sensitive enzyme marker for muscle damage in athletes. Elevated CK levels have been reported in many endurance physical activities…”
Get more information

Chronic Lactate Exposure Decreases Mitochondrial Function by Inhibition of Fatty Acid Uptake and Cardiolipin Alterations in Neonatal Rat Cardiomyocytes by San-Millan, Iñigo, Sparagna, Genevieve C, Chapman, Hailey L, Warkins, Valerie L, Chatfield, Kathryn C, Shuff, Sydney R, Martinez, Janel L, Brooks, George A

“…Lactate is an important signaling molecule with autocrine, paracrine and endocrine properties involved in multiple biological processes including regulation of…”
Get full text

Decreased Fatty Acid Oxidation and Altered Lactate Production during Exercise in Patients with Post-acute COVID-19 Syndrome by de Boer, Esther, Petrache, Irina, Goldstein, Nir M, Olin, J Tod, Keith, Rebecca C, Modena, Brian, Mohning, Michael P, Yunt, Zulma X, San-Millán, Inigo, Swigris, Jeffrey J

Get full text

Thiamine deficiency: a commonly unrecognised but easily treatable condition by Schostak, Tritia, San Millan, Iňigo, Jani, Alkesh, Johnson, Richard Joseph

“…Thiamine is present in many foods and is well recognised as an essential nutrient critical for energy metabolism. While thiamine deficiency is commonly…”
Get full text

Objective assessment of metabolism and guidance of ICU rehabilitation with cardiopulmonary exercise testing by Whittle, John, San-Millán, Iñigo

Get full text

Muscle mass and physical recovery in ICU: innovations for targeting of nutrition and exercise by Wischmeyer, Paul E, Puthucheary, Zudin, San Millán, Iñigo, Butz, Daniel, Grocott, Michael P W

“…We have significantly improved hospital mortality from sepsis and critical illness in last 10 years; however, over this same period we have tripled the number…”
Get full text