Search Results - "San José, Ester"

Triggering the TCR Complex Causes the Downregulation of Nonengaged Receptors by a Signal Transduction-Dependent Mechanism by José, Ester San, Borroto, Aldo, Niedergang, Florence, Alcover, Andrés, Alarcón, Balbino

“…Downregulation of the TCR complex is believed to be intimately tied to T cell activation, allowing serial triggering of receptors and desensitization of…”
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Expression of a Modified Form of CD4 Results in the Release of an Anti-HIV Factor Derived from the Env Sequence by Zaldivar, Irene, Munoz-Fernandez, Maria Angeles, Alarcon, Balbino, San Jose, Ester

“…We have studied the inhibitory effect of a CD4 chimera (CD4epsilon15) on HIV replication. This chimera is retained in the endoplasmic reticulum and traps the…”
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Assembly of the TCR/CD3 complex: CD3ϵ/δ and CD3ϵ/γ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model by San José, Ester, Sahuquillo, Almudena G., Bragado, Rafael, Alarcón, Balbino

“…The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface in a coordinate fashion after assembly in the endoplasmic reticulum…”
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Receptor Engagement Transiently Diverts the T Cell Receptor Heterodimer from a Constitutive Degradation Pathway by Jose, E S, Alarcon, B

“…In the absence of ligand, the T cell receptor (TCR)/CD3 complex is continuously internalized and recycled to the cell surface, whereas receptor engagement…”
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Conformational and Biochemical Differences in the TCR·CD3 Complex of CD8+ Versus CD4+ Mature Lymphocytes Revealed in the Absence of CD3γ by Zapata, David A., Pacheco-Castro, Alberto, Torres, Pilar S., Ramiro, Almudena R., San José, Ester, Alarcón, Balbino, Alibaud, Laeticia, Rubin, Bent, Toribio, Marı́a L., Regueiro, José R.

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Retroviral vector-mediated expression in primary human T cells of an endoplasmic reticulum-retained CD4 chimera inhibits human immunodeficiency virus type-1 replication by San José, E, Muñoz-Fernández, M A, Alarcón, B

“…Intracellular expression of genes that inhibit key steps in the human immunodeficiency virus (HIV-1) replicative cycle could offer an alternative therapy for…”
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Megalomicin Inhibits HIV-1 Replication and Interferes with gp160 Processing by José, Ester San, Muñoz-Fernández, M.Angeles, Alarcón, Balbino

“…The inhibitory effects on HIV replication of megalomicin (MGM), an inhibitor of intra-Golgi vesicle transport, have been studied. In experiments at low…”
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