Search Results - "San Cheang, Wai"

Black Truffle Extract Exerts Antidiabetic Effects through Inhibition of Inflammation and Lipid Metabolism Regulation by Wu, Ziyuan, Jayachandran, Muthukumaran, Cheang, Wai San, Xu, Baojun

“…Black truffle, a culinary and medical fungus, is highly valued worldwide for its nutritional and therapeutic importance. To enhance the existing knowledge…”
Get full text

Roles and Therapeutic Implications of Endoplasmic Reticulum Stress and Oxidative Stress in Cardiovascular Diseases by Zhou, Yan, Murugan, Dharmani Devi, Khan, Haroon, Huang, Yu, Cheang, Wai San

“…In different pathological states that cause endoplasmic reticulum (ER) calcium depletion, altered glycosylation, nutrient deprivation, oxidative stress, DNA…”
Get full text

Two methoxy derivatives of resveratrol, 3,3′,4,5′-tetramethoxy-trans-stilbene and 3,4′,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF-κB pathways in RAW 264.7 cells by Zhou, Chunxiu, Zhang, Xutao, Ruan, Cheng-Chao, Cheang, Wai San

“…Abstract Background 3,3′,4,5′-tetramethoxy- trans -stilbene (3,3′,4,5′-TMS) and 3,4′,5-trimethoxy- trans -stilbene (3,4′,5-TMS) are two methoxy derivatives of…”
Get full text

Oxyresveratrol reduces lipopolysaccharide-induced inflammation and oxidative stress through inactivation of MAPK and NF-κB signaling in brain endothelial cells by Zhou, Yan, Deng, Qiaowen, Vong, Chi Teng, Khan, Haroon, Cheang, Wai San

“…Inflammatory responses and oxidative stress damage the integrity of the blood-brain barrier (BBB), which is a primary pathological modulator of…”
Get full text

3,4′,5-Trimethoxy-trans-stilbene Alleviates Endothelial Dysfunction in Diabetic and Obese Mice via Activation of the AMPK/SIRT1/eNOS Pathway by Zhou, Chunxiu, Tan, Yi, Xu, Baojun, Wang, Yitao, Cheang, Wai-San

“…3,4′,5-trimethoxy-trans-stilbene (TMS) is a methoxylated derivative of resveratrol. Previous studies showed the vaso-protective effects of resveratrol;…”
Get full text

Anti-diabetic potential of apigenin, luteolin, and baicalein via partially activating PI3K/Akt/Glut-4 signaling pathways in insulin-resistant HepG2 cells by Miao, Lingchao, Zhang, Haolin, Cheong, Meng Sam, Zhong, Ruting, Garcia-Oliveira, Paula, Prieto, Miguel A., Cheng, Ka-Wing, Wang, Mingfu, Cao, Hui, Nie, Shaoping, Simal-Gandara, Jesus, Cheang, Wai San, Xiao, Jianbo

“…Dietary flavonoids are abundant in natural plants and possess multiple pharmacological and nutritional activities. In this study, apigenin, luteolin, and…”
Get full text

Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress by San Cheang, Wai, Yuen Ngai, Ching, Yen Tam, Ye, Yu Tian, Xiao, Tak Wong, Wing, Zhang, Yang, Wai Lau, Chi, Chen, Zhen Yu, Bian, Zhao-Xiang, Huang, Yu, Ping Leung, Fung

“…Hypertensive patients have been found to be associated with elevated levels of homocysteine, known as hyperhomocysteinemia. Homocysteine (Hcy) can induce…”
Get full text

Analysis of Flavonoid Metabolites in Citrus reticulata ‘Chachi’ at Different Collection Stages Using UPLC-ESI-MS/MS by Chen, Yuting, Xu, Yujuan, Wen, Jing, Yu, Yuanshan, Wu, Jijun, Cheng, Lina, Cheang, Wai-San, Liu, Wenwen, Fu, Manqin

“…Flavonoids are essential substances with antioxidant properties and high medicinal value. Citrus reticulata ‘Chachi’ peel (CRCP) is rich in flavonoids and has…”
Get full text

Activation of AMPK/miR-181b Axis Alleviates Endothelial Dysfunction and Vascular Inflammation in Diabetic Mice by Cheng, Chak-Kwong, Shang, Wenbin, Liu, Jian, Cheang, Wai-San, Wang, Yu, Xiang, Li, Lau, Chi-Wai, Luo, Jiang-Yun, Ng, Chi-Fai, Huang, Yu, Wang, Li

“…Hyperglycemia in diabetes mellitus impairs endothelial function and disrupts microRNA (miRNA) profiles in vasculature, increasing the risk of…”
Get full text

Apigenin alleviates diabetic endothelial dysfunction through activating AMPK/PI3K/Akt/eNOS and Nrf2/HO‐1 signaling pathways by Miao, Lingchao, Cheong, Meng Sam, Zhou, Chunxiu, Farag, Mohamed, Cheang, Wai San, Xiao, Jianbo

“…Apigenin (4′,5,7‐trihydroxyflavone) is a natural flavone reported to present anti‐diabetic and anti‐oxidative bioactivities. The effect of apigenin to mitigate…”
Get full text

Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease by Zhou, Yan, Khan, Haroon, Xiao, Jianbo, Cheang, Wai San

“…Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes and metabolized by cyclooxygenase (COX), cytochrome P450…”
Get full text

Neuroprotective Effects of Quercetin in Alzheimer's Disease by Khan, Haroon, Ullah, Hammad, Aschner, Michael, Cheang, Wai San, Akkol, Esra Küpeli

“…Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic potential. It is widely distributed among plants and found commonly in…”
Get full text

Editorial for the Special Issue "Bioactive Compounds of Natural Products on Metabolic Disorders and Complications" by Cheang, Wai San

“…Metabolic disorders are complex abnormalities involving impaired glucose and lipid metabolism, associated with complications such as kidney disease,…”
Get full text

Pleiotropic Effects of Peroxisome Proliferator-Activated Receptor γ and δ in Vascular Diseases by Cheang, Wai San, Fang, Xi, Tian, Xiao Yu

“…Peroxisome proliferator-activated receptors gamma (PPARγ) and delta (PPARδ) are nuclear receptors that have significant physiological effects on glucose and…”
Get full text

Modifications of dietary flavonoids towards improved bioactivity: An update on structure-activity relationship by Chen, Lei, Teng, Hui, Xie, Zhenglu, Cao, Hui, Cheang, Wai San, Skalicka-Woniak, Krystyna, Georgiev, Milen I., Xiao, Jianbo

“…Over the past two decades, extensive studies have revealed that inflammation represents a major risk factor for various human diseases. Chronic inflammatory…”
Get full text

Effects of domestic cooking process on the chemical and biological properties of dietary phytochemicals by Zhao, Chao, Liu, Yuanyuan, Lai, Shanshan, Cao, Hui, Guan, Yi, San Cheang, Wai, Liu, Bin, Zhao, Kewei, Miao, Song, Riviere, Céline, Capanoglu, Esra, Xiao, Jianbo

“…Foods are good sources of vitamins, minerals and dietary fibers as well as phytochemicals, which are beneficial for the human body as nutritional supplements…”
Get full text

Resveratrol regulates inflammation and improves oxidative stress via Nrf2 signaling pathway: Therapeutic and biotechnological prospects by Shahcheraghi, Seyed Hossein, Salemi, Fateme, Small, Shlomo, Syed, Suliman, Salari, Farzam, Alam, Waqas, Cheang, Wai San, Saso, Luciano, Khan, Haroon

“…Usually, in aerobic metabolism, natural materials including nucleic acids, proteins, and lipids can experience auxiliary injury by oxidative responses. This…”
Get full text

Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus by Zhao, Chao, Yang, Chengfeng, Wai, Sydney Tang Chi, Zhang, Yanbo, P. Portillo, Maria, Paoli, Paolo, Wu, Yijing, San Cheang, Wai, Liu, Bin, Carpéné, Christian, Xiao, Jianbo, Cao, Hui

“…Type 2 diabetes mellitus (T2DM) is the most prevalent disease and becoming a serious public health threat worldwide. It is a severe endocrine metabolic…”
Get full text

Effects of aging on the bioactive flavonoids and fungal diversity of Pericarpium Citri Reticulatae (Citrus reticulata ‘Chachi’) by Chen, Linhong, Xiao, Gengsheng, Xu, Yujuan, Cheang, Wai San, Wu, Jijun, Yu, Yuanshan, Wen, Jing, Fu, Manqin

“…Samples of Pericarpium Citri Reticulatae (Citrus reticulata 'Chachi', CP-‘Chachi’), which collected in December of 2017, 2013, 2003 and 1993 with the natural…”
Get full text

Isoflavones daidzin and daidzein inhibit lipopolysaccharide-induced inflammation in RAW264.7 macrophages by Tan, Yi, Zhang, Xutao, Cheang, Wai San

“…Abstract Background Inflammation contributes to various diseases and soybeans and legumes are shown to reduce inflammation. However, the bioactive ingredients…”
Get full text