Search Results - "San, K.Y"
-
1
Expression of the Arabidopsis feedback-insensitive anthranilate synthase holoenzyme and tryptophan decarboxylase genes in Catharanthus roseus hairy roots
Published in Journal of biotechnology (09-03-2006)“…In plants, the indole pathway provides precursors for a variety of secondary metabolites. In Catharanthus roseus, a decarboxylated derivative of tryptophan,…”
Get full text
Journal Article -
2
Expression of a feedback-resistant anthranilate synthase in Catharanthus roseus hairy roots provides evidence for tight regulation of terpenoid indole alkaloid levels
Published in Biotechnology and bioengineering (20-06-2004)“…Different plant species produce a variety of terpenoid indole alkaloids, which are of interest as plant defensive secondary metabolites and as valuable…”
Get full text
Journal Article -
3
-
4
Terpenoid indole alkaloid production by Catharanthus roseus hairy roots induced by Agrobacterium tumefaciens harboring rol ABC genes
Published in Biotechnology and bioengineering (05-02-2006)“…We have established Catharanthus roseus hairy root cultures transgenic for the rol ABC genes from T(L)-DNA of the agropine-type Agrobacterium rhizogenes strain…”
Get full text
Journal Article -
5
Effects of terpenoid precursor feeding on Catharanthus roseus hairy roots over-expressing the alpha or the alpha and beta subunits of anthranilate synthase
Published in Biotechnology and bioengineering (20-02-2006)“…Among the pharmacologically important terpenoid indole alkaloids produced by Catharanthus roseus are the anti-cancer drugs vinblastine and vincristine. These…”
Get full text
Journal Article -
6
Characterization of an Ethanol-Inducible Promoter System in Catharanthus roseus Hairy Roots
Published in Biotechnology progress (01-09-2007)“…Efforts to engineer Catharanthus roseus hairy roots to produce commercially significant amounts of valuable compounds, such as the terpenoid indole alkaloids…”
Get full text
Journal Article -
7
Long-Term Maintenance of a Transgenic Catharanthus roseus Hairy Root Line
Published in Biotechnology progress (01-11-2007)“…Stably transformed transgenic hairy root cultures have the potential to be a valuable production platform for a variety of secondary metabolites. This study…”
Get full text
Journal Article -
8
Transient effects of overexpressing anthranilate synthase α and β subunits in Catharanthus roseus hairy roots
Published in Biotechnology progress (01-09-2005)“…Catharanthus roseus produces two economically valuable anticancer drugs, vinblastine and vincristine. These drugs are members of the terpenoid indole alkaloids…”
Get full text
Journal Article -
9
Effect of the Engineered Indole Pathway on Accumulation of Phenolic Compounds in Catharanthus roseus Hairy Roots
Published in Biotechnology progress (01-03-2007)“…Catharanthus roseus has been well‐known to contain indole alkaloids effective for treatment of diverse cancers. We examined the intracellular accumulation…”
Get full text
Journal Article -
10
Role of the non-mevalonate pathway in indole alkaloid production by Catharanthus roseus hairy roots
Published in Biotechnology progress (01-05-2003)“…The 1‐deoxy‐d‐xylulose‐5‐phosphate (DXP) pathway (non‐mevalonate pathway) leading to terpenoids via isopentenyl diphosphate (IPP) has been shown to occur in…”
Get full text
Journal Article -
11
Optimal Feedback Control of a Bioreactor with a Remote Sensor
Published in 1988 American Control Conference (01-06-1988)“…Sensors used to monitor bioreactor conditions directly often perform poorly in the face of adverse nonphysiological conditions. One way to circumvent this is…”
Get full text
Conference Proceeding -
12
Enhanced plasmid maintenance in a CSTR upon square-wave oscillations in the dilution rate
Published in Biotechnology letters (01-08-1988)“…The effects of forced square-wave perturbations in the dilution rate on plasmid maintenance and gene expression of a population of Escherichia coli K12 strain…”
Get full text
Journal Article -
13
Plasmid maintenance and gene expression of a recombinant culture under aerobic and anaerobic conditions
Published in Biotechnology letters (01-06-1988)“…The stability and gene expression of a batch culture of Escherichia coli , strain C6000, carrying the plasmid pKN401 under both aerobic and anaerobic…”
Get full text
Journal Article