Search Results - "Samuelson, C."

Notch regulation of gastrointestinal stem cells by Demitrack, Elise S., Samuelson, Linda C.

“…The gastrointestinal (GI) tract epithelium is continuously replenished by actively cycling stem and progenitor cells. These cell compartments are regulated to…”
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Enzymatic methyl sequencing detects DNA methylation at single-base resolution from picograms of DNA by Vaisvila, Romualdas, Ponnaluri, V.K. Chaithanya, Sun, Zhiyi, Langhorst, Bradley W., Saleh, Lana, Guan, Shengxi, Dai, Nan, Campbell, Matthew A., Sexton, Brittany S., Marks, Katherine, Samaranayake, Mala, Samuelson, James C., Church, Heidi E., Tamanaha, Esta, Corrêa, Ivan R., Pradhan, Sriharsa, Dimalanta, Eileen T., Evans, Thomas C., Williams, Louise, Davis, Theodore B.

“…Bisulfite sequencing detects 5mC and 5hmC at single-base resolution. However, bisulfite treatment damages DNA, which results in fragmentation, DNA loss, and…”
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Debate over the identity of an intestinal niche-cell population settled by Samuelson, Linda C.

“…The cellular microenvironment required to sustain adult intestinal stem cells has long been controversial. Cells that release proteins needed for…”
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Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate by VanDussen, Kelli L., Samuelson, Linda C.

“…The Notch-regulated transcription factor mouse atonal homolog 1 (Math1) is required for the development of intestinal secretory cells, as demonstrated by the…”
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Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells by VanDussen, Kelli L, Carulli, Alexis J, Keeley, Theresa M, Patel, Sanjeevkumar R, Puthoff, Brent J, Magness, Scott T, Tran, Ivy T, Maillard, Ivan, Siebel, Christian, Kolterud, Åsa, Grosse, Ann S, Gumucio, Deborah L, Ernst, Stephen A, Tsai, Yu-Hwai, Dempsey, Peter J, Samuelson, Linda C

“…Notch signaling is known to regulate the proliferation and differentiation of intestinal stem and progenitor cells; however, direct cellular targets and…”
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Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation by Hibdon, Elise S., Razumilava, Nataliya, Keeley, Theresa M., Wong, Gabriela, Solanki, Sumeet, Shah, Yatrik M., Samuelson, Linda C.

“…Notch pathway signaling is known to promote gastric stem cell proliferation, and constitutive pathway activation induces gastric tumors via mTORC1 activation…”
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Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration by Carulli, Alexis J., Keeley, Theresa M., Demitrack, Elise S., Chung, Jooho, Maillard, Ivan, Samuelson, Linda C.

“…The Notch signaling pathway regulates intestinal epithelial cell homeostasis, including stem cell maintenance, progenitor cell proliferation and…”
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Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach by Choi, Eunyoung, Lantz, Tyler L, Vlacich, Gregory, Keeley, Theresa M, Samuelson, Linda C, Coffey, Robert J, Goldenring, James R, Powell, Anne E

“…Lrig1 is a marker of proliferative and quiescent stem cells in the skin and intestine. We examined whether Lrig1-expressing cells are long-lived gastric…”
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The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease by Choi, Eun-Kyung, Rajendiran, Thekkelnaycke M., Soni, Tanu, Park, Jin-Ho, Aring, Luisa, Muraleedharan, Chithra K., Garcia-Hernandez, Vicky, Kamada, Nobuhiko, Samuelson, Linda C., Nusrat, Asma, Iwase, Shigeki, Seo, Young Ah

“…The metal ion transporter SLC39A8 is associated with physiological traits and diseases, including blood manganese (Mn) levels and inflammatory bowel diseases…”
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Notch signaling regulates gastric antral LGR5 stem cell function by Demitrack, Elise S, Gifford, Gail B, Keeley, Theresa M, Carulli, Alexis J, VanDussen, Kelli L, Thomas, Dafydd, Giordano, Thomas J, Liu, Zhenyi, Kopan, Raphael, Samuelson, Linda C

“…The major signaling pathways regulating gastric stem cells are unknown. Here we report that Notch signaling is essential for homeostasis of LGR5 + antral stem…”
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Blockade of individual Notch ligands and receptors controls graft-versus-host disease by Tran, Ivy T, Sandy, Ashley R, Carulli, Alexis J, Ebens, Christen, Chung, Jooho, Shan, Gloria T, Radojcic, Vedran, Friedman, Ann, Gridley, Thomas, Shelton, Amy, Reddy, Pavan, Samuelson, Linda C, Yan, Minhong, Siebel, Christian W, Maillard, Ivan

“…Graft-versus-host disease (GVHD) is the main complication of allogeneic bone marrow transplantation. Current strategies to control GVHD rely on global…”
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Engineering Escherichia coli BL21(DE3) Derivative Strains To Minimize E. coli Protein Contamination after Purification by Immobilized Metal Affinity Chromatography by ROBICHON, Carine, JIANYING LUO, CAUSEY, Thomas B, BENNER, Jack S, SAMUELSON, James C

“…OA  Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides by Chen, Minyong, Shi, Xiaofeng, Duke, Rebecca M., Ruse, Cristian I., Dai, Nan, Taron, Christopher H., Samuelson, James C.

“…A method for selective and comprehensive enrichment of N-linked glycopeptides was developed to facilitate detection of micro-heterogeneity of N-glycosylation…”
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Notch as a Driver of Gastric Epithelial Cell Proliferation by Demitrack, Elise S, Samuelson, Linda C

“…The gastric epithelium is sustained by a population of stem cells that replenish the various mature epithelial lineages throughout adulthood. Regulation of…”
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Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis by Gifford, Gail B, Demitrack, Elise S, Keeley, Theresa M, Tam, Andrew, La Cunza, Nilsa, Dedhia, Priya H, Spence, Jason R, Simeone, Diane M, Saotome, Ichiko, Louvi, Angeliki, Siebel, Christian W, Samuelson, Linda C

“…We tested the ability of Notch pathway receptors Notch1 and Notch2 to regulate stem and epithelial cell homoeostasis in mouse and human gastric antral tissue…”
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Identification, isolation and characterization of human LGR5-positive colon adenoma cells by Dame, Michael K, Attili, Durga, McClintock, Shannon D, Dedhia, Priya H, Ouillette, Peter, Hardt, Olaf, Chin, Alana M, Xue, Xiang, Laliberte, Julie, Katz, Erica L, Newsome, Gina M, Hill, David R, Miller, Alyssa J, Tsai, Yu-Hwai, Agorku, David, Altheim, Christopher H, Bosio, Andreas, Simon, Becky, Samuelson, Linda C, Stoerker, Jay A, Appelman, Henry D, Varani, James, Wicha, Max S, Brenner, Dean E, Shah, Yatrik M, Spence, Jason R, Colacino, Justin A

“…The intestine is maintained by stem cells located at the base of crypts and distinguished by the expression of LGR5. Genetically engineered mouse models have…”
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NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus by Demitrack, Elise S, Gifford, Gail B, Keeley, Theresa M, Horita, Nobukatsu, Todisco, Andrea, Turgeon, D Kim, Siebel, Christian W, Samuelson, Linda C

“…The Notch signaling pathway is known to regulate stem cells and epithelial cell homeostasis in gastrointestinal tissues; however, Notch function in the corpus…”
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Gastric Sonic Hedgehog Acts as a Macrophage Chemoattractant During the Immune Response to Helicobacter pylori by Schumacher, Michael A, Donnelly, Jessica M, Engevik, Amy C, Xiao, Chang, Yang, Li, Kenny, Susan, Varro, Andrea, Hollande, Frédéric, Samuelson, Linda C, Zavros, Yana

“…Background & Aims Macrophages mediate the epithelial response to Helicobacter pylori and are involved in the development of gastritis. Sonic Hedgehog (Shh)…”
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Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle by Sahoo, Nirakar, Gu, Mingxue, Zhang, Xiaoli, Raval, Neel, Yang, Junsheng, Bekier, Michael, Calvo, Raul, Patnaik, Samarjit, Wang, Wuyang, King, Greyson, Samie, Mohammad, Gao, Qiong, Sahoo, Sasmita, Sundaresan, Sinju, Keeley, Theresa M., Wang, Yanzhuang, Marugan, Juan, Ferrer, Marc, Samuelson, Linda C., Merchant, Juanita L., Xu, Haoxing

“…Gastric acid secretion by parietal cells requires trafficking and exocytosis of H/K-ATPase-rich tubulovesicles (TVs) toward apical membranes in response to…”
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CAnceR IN PreGnancy (CARING) – a retrospective study of cancer diagnosed during pregnancy in the United Kingdom by Baxter, M. A., Denholm, M., Kingdon, S. J., Kathirgamakarthigeyan, S., Parikh, S., Shakir, R., Johnson, R., Martin, H., Walton, M., Yao, W., Swan, A., Samuelson, C., Ren, X., Cooper, A., Gray, H-L, Clifton, S., Ball, J., Gullick, G., Anderson, M., Dodd, L., Hayhurst, H., Salama, M., Shotton, R., Britton, F., Christodoulou, T., Abdul-Hamid, A., Eichholz, A., Evans, R. M., Wallroth, P., Gibson, F., Poole, K., Rowe, M., Harris, J.

“…Background The incidence of cancer diagnosed during pregnancy is increasing. Data relating to investigation and management, as well as maternal and foetal…”
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