Search Results - "Samuel, Catherine"
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Rapid diagnosis of cryptococcal meningitis by use of lateral flow assay on cerebrospinal fluid samples: influence of the high-dose "hook" effect
Published in Journal of clinical microbiology (01-12-2014)“…Cryptococcal meningitis is the most frequent cause of meningitis and a major cause of mortality in HIV-infected adults in Africa. This study evaluated the…”
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Improved detection of Pneumocystis jirovecii in upper and lower respiratory tract specimens from children with suspected pneumocystis pneumonia using real-time PCR: a prospective study
Published in BMC infectious diseases (28-11-2011)“…Pneumocystis pneumonia (PCP) is a major cause of hospitalization and mortality in HIV-infected African children. Microbiologic diagnosis relies predominantly…”
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3
Pneumocystis pneumonia in South African children diagnosed by molecular methods
Published in BMC research notes (10-01-2014)“…Pneumocystis pneumonia (PCP) is an important cause of hospitalization and mortality in HIV-infected children. However, the incidence of PCP has been…”
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In vitro activity of ceftazidime-avibactam against clinical isolates of Enterobacterales and Pseudomonas aeruginosa from sub-Saharan Africa: ATLAS Global Surveillance Program 2017–2021
Published in Journal of global antimicrobial resistance. (01-12-2023)“…•96.2% of all Enterobacterales isolates were ceftazidime-avibactam-susceptible.•Most ceftazidime-avibactam-resistant Enterobacterales isolates carried MBL…”
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Epidemiologic Shift in Candidemia Driven by Candida auris, South Africa, 2016-2017
Published in Emerging infectious diseases (01-09-2019)“…Candida auris is an invasive healthcare-associated fungal pathogen. Cases of candidemia, defined as illness in patients with Candida cultured from blood, were…”
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In Vitro Antifungal Resistance of Candida auris Isolates from Bloodstream Infections, South Africa
Published in Antimicrobial agents and chemotherapy (17-08-2021)“…Candida auris is a multidrug-resistant fungal pathogen that is endemic in South African hospitals. We tested bloodstream C. auris isolates that were submitted…”
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Pneumocystis jirovecii infection of the external auditory canal
Published in Southern African journal of HIV medicine (01-09-2010)“…Pneumocystis jirovecii is well known to cause interstitial plasma cell pneumonia in immunocompromised patients. It has been implicated as a rare cause of…”
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8
Multi-channel MRI Embedding: An Effective Strategy for Enhancing Brain Tumor Segmentation
Published in 2021 IEEE Applied Imagery Pattern Recognition Workshop (AIPR) (12-10-2021)“…A brain tumor is a collection or a mass of abnormal cells in the brain. One of the most important diagnostic tasks in medical image processing is the brain…”
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Conference Proceeding -
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Outcomes of flucytosine-containing combination treatment for cryptococcal meningitis in a South African national access programme: a cross-sectional observational study
Published in The Lancet infectious diseases (01-09-2022)“…Although flucytosine is a key component of WHO-recommended induction treatment for HIV-associated cryptococcal meningitis, this antifungal agent is not widely…”
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10
Candida auris Clinical Isolates Associated with Outbreak in Neonatal Unit of Tertiary Academic Hospital, South Africa
Published in Emerging infectious diseases (01-10-2023)“…Candida auris was first detected at a university-affiliated hospital in Johannesburg, South Africa, in 2009. We used whole-genome sequencing to describe the…”
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Impact of prior cryptococcal antigen screening on in-hospital mortality in cryptococcal meningitis or fungaemia among HIV-seropositive individuals in South Africa: a cross-sectional observational study
Published in Clinical microbiology and infection (01-08-2023)“…We investigated whether patients with cryptococcal meningitis (CM) or fungaemia detected through South Africa's laboratory cryptococcal antigen (CrAg)…”
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HIV Infection as Risk Factor for Death among Hospitalized Persons with Candidemia, South Africa, 2012-2017
Published in Emerging infectious diseases (01-06-2021)“…We determined the effect of HIV infection on deaths among persons >18 months of age with culture-confirmed candidemia at 29 sentinel hospitals in South Africa…”
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Epidemiology and susceptibility of Nakaseomyces (formerly Candida) glabrata bloodstream isolates from hospitalised adults in South Africa
Published in Medical mycology (Oxford) (05-06-2023)“…Abstract During 2016–2017, Nakaseomyces glabrata (formerly Candida glabrata) caused 14% of cases of candidaemia in South Africa. We aimed to describe the…”
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Declining Incidence of Invasive Meningococcal Disease in South Africa: 2003-2016
Published in Clinical infectious diseases (18-07-2019)“…Invasive meningococcal disease (IMD) is endemic to South Africa, where vaccine use is negligible. We describe the epidemiology of IMD in South Africa. IMD…”
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Long-term effect of pneumococcal conjugate vaccines on invasive pneumococcal disease incidence among people of all ages from national, active, laboratory-based surveillance in South Africa, 2005–19: a cohort observational study
Published in The Lancet global health (01-09-2024)“…In South Africa, 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in 2009 and 13-valent PCV (PCV13) was introduced in 2011, both in a two plus one…”
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Carbapenem-resistant Enterobacterales among hospitalized patients in Cape Town, South Africa: clinical and microbiological epidemiology
Published in JAC-antimicrobial resistance (01-04-2024)“…Abstract Background Carbapenem-resistant Enterobacterales (CRE) are a substantial problem in Cape Town. CRE epidemiology is largely unknown and mortality…”
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Carbapenem-resistant Klebsiella pneumoniae among hospitalized patients in Cape Town, South Africa: molecular epidemiology and characterization
Published in JAC-antimicrobial resistance (01-04-2024)“…Abstract Background The molecular epidemiology of carbapenem-resistant Enterobacterales in Cape Town remains largely unknown. Objectives This study aimed to…”
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AIDS-related mycoses: the way forward
Published in Trends in microbiology (01-03-2014)“…The contribution of fungal infections to the morbidity and mortality of HIV-infected individuals is largely unrecognized. A recent meeting highlighted several…”
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Journal Article Conference Proceeding -
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Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa: phenotypic and genotypic analysis of isolates
Published in BMC infectious diseases (29-09-2017)“…Workers in clinical microbiology laboratories are exposed to a variety of pathogenic microorganisms. Salmonella species is among the most commonly reported…”
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Pneumocystis jirovecii infection of the external auditory canal : case study
Published in Southern African journal of HIV medicine (01-09-2010)“…Pneumocystis jirovecii is well known to cause interstitial plasma cell pneumonia in immunocompromised patients. It has been implicated as a rare cause of…”
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Journal Article