Search Results - "Samuel, Aravinthan D T"
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Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel
Published in Nature (London) (01-03-2018)“…Stem cells of the Drosophila midgut sense mechanical signals in vivo through the stretch-activated ion channel Piezo, which is expressed on previously…”
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Pan-neuronal imaging in roaming Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (23-02-2016)“…We present an imaging system for pan-neuronal recording in crawling Caenorhabditis elegans. A spinning disk confocal microscope, modified for automated…”
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3
Two alternating motor programs drive navigation in Drosophila larva
Published in PloS one (15-08-2011)“…When placed on a temperature gradient, a Drosophila larva navigates away from excessive cold or heat by regulating the size, frequency, and direction of…”
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4
Sensory determinants of behavioral dynamics in Drosophila thermotaxis
Published in Proceedings of the National Academy of Sciences - PNAS (13-01-2015)“…Complex animal behaviors are built from dynamical relationships between sensory inputs, neuronal activity, and motor outputs in patterns with strategic value…”
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5
Monoaminergic orchestration of motor programs in a complex C. elegans behavior
Published in PLoS biology (01-04-2013)“…Monoamines provide chemical codes of behavioral states. However, the neural mechanisms of monoaminergic orchestration of behavior are poorly understood. Touch…”
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Biomechanical analysis of gait adaptation in the nematode Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2010)“…To navigate different environments, an animal must be able to adapt its locomotory gait to its physical surroundings. The nematode Caenorhabditis elegans,…”
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7
Functional diversity among sensory receptors in a Drosophila olfactory circuit
Published in Proceedings of the National Academy of Sciences - PNAS (04-06-2013)“…The ability of an animal to detect, discriminate, and respond to odors depends on the function of its olfactory receptor neurons (ORNs), which in turn depends…”
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Navigational Decision Making in Drosophila Thermotaxis
Published in The Journal of neuroscience (24-03-2010)“…A mechanistic understanding of animal navigation requires quantitative assessment of the sensorimotor strategies used during navigation and quantitative…”
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9
The wiring diagram of a glomerular olfactory system
Published in eLife (13-05-2016)“…The sense of smell enables animals to react to long-distance cues according to learned and innate valences. Here, we have mapped with electron microscopy the…”
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10
Dopamine signaling is essential for precise rates of locomotion by C. elegans
Published in PloS one (13-06-2012)“…Dopamine is an important neuromodulator in both vertebrates and invertebrates. We have found that reduced dopamine signaling can cause a distinct abnormality…”
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11
The AFD Sensory Neurons Encode Multiple Functions Underlying Thermotactic Behavior in Caenorhabditis elegans
Published in The Journal of neuroscience (12-07-2006)“…The thermotactic behaviors of Caenorhabditis elegans indicate that its thermosensory system exhibits exquisite temperature sensitivity, long-term plasticity,…”
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12
Two size-selective mechanisms specifically trap bacteria-sized food particles in Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (24-11-2009)“…Caenorhabditis elegans is a filter feeder: it draws bacteria suspended in liquid into its pharynx, traps the bacteria, and ejects the liquid. How pharyngeal…”
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13
An Olfactory Neuron Responds Stochastically to Temperature and Modulates Caenorhabditis elegans Thermotactic Behavior
Published in Proceedings of the National Academy of Sciences - PNAS (05-08-2008)“…Caenorhabditis elegans navigates thermal gradients by using a behavioral strategy that is regulated by a memory of its cultivation temperature $(T_{{\rm c}})$…”
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14
C. elegans locomotion: small circuits, complex functions
Published in Current opinion in neurobiology (01-08-2015)“…Highlights • The Caenorhabditis elegans motor circuit has a nearly complete connectome. • Neurogenetic studies are unveiling a rich and complex set of…”
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15
Probing and manipulating embryogenesis via nanoscale thermometry and temperature control
Published in Proceedings of the National Academy of Sciences - PNAS (30-06-2020)“…Understanding the coordination of cell-division timing is one of the outstanding questions in the field of developmental biology. One active control parameter…”
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Neural Circuits Mediate Electrosensory Behavior in Caenorhabditis elegans
Published in The Journal of neuroscience (11-07-2007)“…The nematode Caenorhabditis elegans deliberately crawls toward the negative pole in an electric field. By quantifying the movements of individual worms…”
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Olfactory Behavior of Swimming C. elegans Analyzed by Measuring Motile Responses to Temporal Variations of Odorants
Published in Journal of neurophysiology (01-05-2008)“…1 Departments of Physics and 2 Organismic and Evolutionary Biology and 3 Center for Brain Science, Harvard University, Cambridge, Massachusetts Submitted 15…”
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18
Mechanosensation and mechanical load modulate the locomotory gait of swimming C. elegans
Published in Journal of experimental biology (01-07-2007)“…Animals move through their environments by selecting gaits that are adapted to the physical nature of their surroundings. The nematode Caenorhabditis elegans…”
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Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans
Published in Development (Cambridge) (01-03-2008)“…The molecular and cellular mechanisms that allow adult-stage neurons to regenerate following damage are poorly understood. Recently, axons of motoneurons and…”
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Temporal Activity Patterns in Thermosensory Neurons of Freely Moving Caenorhabditis elegans Encode Spatial Thermal Gradients
Published in The Journal of neuroscience (06-06-2007)“…Our understanding of the operation of neurons and neuronal circuits has come primarily from probing their activity in dissected, anesthetized, or restrained…”
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