Health-Promoting and Therapeutic Attributes of Milk-Derived Bioactive Peptides

Health-Promoting and Therapeutic Attributes of Milk-Derived Bioactive Peptides

Milk-derived bioactive peptides (BAPs) possess several potential attributes in terms of therapeutic capacity and their nutritional value. BAPs from milk proteins can be liberated by bacterial fermentation, in vitro enzymatic hydrolysis, food processing, and gastrointestinal digestion. Previous evide...

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Bibliographic Details
Published in:Nutrients Vol. 14; no. 15; p. 3001
Main Authors: Samtiya, Mrinal, Samtiya, Sweta, Badgujar, Prarabdh C., Puniya, Anil Kumar, Dhewa, Tejpal, Aluko, Rotimi E.
Format: Journal Article
Language:English
Published: Basel MDPI AG 22-07-2022
MDPI
Subjects:
Amino acids
anti-diabetic
anti-hypertensive
anti-inflammation
Antidiabetics
Antihypertensives
Antiinfectives and antibacterials
bioactive peptides
Biological activity
Biomedical materials
Commercialization
Dairy products
Diabetes
Diabetes mellitus
Digestive system
Enzymes
Fermentation
Food
Food processing
Gastrointestinal tract
Health promotion
Hypertension
In vivo methods and tests
Lipids
Microbial activity
Microorganisms
Milk
milk proteins
Molecular weight
Nutritive value
Peptides
Proteins
Review
therapeutic potentials
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Summary:Milk-derived bioactive peptides (BAPs) possess several potential attributes in terms of therapeutic capacity and their nutritional value. BAPs from milk proteins can be liberated by bacterial fermentation, in vitro enzymatic hydrolysis, food processing, and gastrointestinal digestion. Previous evidence suggested that milk protein-derived BAPs have numerous health-beneficial characteristics, including anti-cancerous activity, anti-microbial activity, anti-oxidative, anti-hypertensive, lipid-lowering, anti-diabetic, and anti-osteogenic. In this literature overview, we briefly discussed the production of milk protein-derived BAPs and their mechanisms of action. Milk protein-derived BAPs are gaining much interest worldwide due to their immense potential as health-promoting agents. These BAPs are now used to formulate products sold in the market, which reflects their safety as natural compounds. However, enhanced commercialization of milk protein-derived BAPs depends on knowledge of their particular functions/attributes and safety confirmation using human intervention trials. We have summarized the therapeutic potentials of these BAPs based on data from in vivo and in vitro studies.
Bibliography:ObjectType-Article-2
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ISSN:2072-6643
2072-6643
DOI:10.3390/nu14153001