Search Results - "Samsuddin, Salma"
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Periodontitis is associated with significant hepatic fibrosis in patients with non-alcoholic fatty liver disease
Published in PloS one (08-12-2017)“…Non-alcoholic fatty liver disease (NAFLD) has a bidirectional association with metabolic syndrome. It affects up to 30% of the general population, 70% of…”
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Screening of Neonatal UK Dried Blood Spots Using a Duplex SMN1 Screening Assay
Published in International journal of neonatal screening (26-10-2021)“…Spinal muscular atrophy (SMA) is an autosomal inherited neuromuscular genetic disease caused, in 95% of cases, by homozygous deletions involving the SMN1 gene…”
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β-Actin regulates platelet nitric oxide synthase 3 activity through interaction with heat shock protein 90
Published in Proceedings of the National Academy of Sciences - PNAS (22-05-2007)“…Cytoskeletal proteins are crucial in maintaining cellular structure and, in certain cell types, also play an essential role in motility and shape change…”
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The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo
Published in PloS one (12-10-2009)“…Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARalpha, -beta/delta, and -gamma) nuclear receptors. In particular, PPARalpha is…”
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5
Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease
Published in Bioscience reports (31-01-2020)“…Noninvasive biomarkers are clinically useful for evaluating liver fibrosis stage in patients with nonalcoholic fatty liver disease (NAFLD). The aim of the…”
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Development of an academic disease registry for spinal muscular atrophy
Published in Neuromuscular disorders : NMD (01-10-2019)“…•We report the development of the new disease registry: International SMA Registry.•The aim was to establish a system for collection of highly curated…”
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The Epoxygenases CYP2J2 Activates the Nuclear Receptor PPARα In Vitro and In Vivo
Published in PloS one (12-10-2009)“…Background Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARα, -β/δ, and -γ) nuclear receptors. In particular, PPARα is involved…”
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Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of South Asian descent
Published in Frontline gastroenterology (01-04-2018)“…ObjectiveLiver biopsy is the most accurate method for determining stage and grade of injury in non-alcoholic fatty liver disease (NAFLD). Given risks and…”
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The role of PPARs in modulating cardiac metabolism in diabetes
Published in Pharmacological research (01-09-2009)“…Diabetes mellitus is an important risk factor for the development of cardiovascular disease. The impact of diabetes on the heart in part resides in the changes…”
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The Epoxygenases CYP2J2 Activates the Nuclear Receptor PPAR[alpha] In Vitro and In Vivo
Published in PloS one (12-10-2009)“…Background Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPAR[alpha], -[beta]/[delta], and -[gamma]) nuclear receptors. In…”
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11
The Epoxygenases CYP2J2 Activates the Nuclear Receptor PPARI- In Vitro and In Vivo
Published in PloS one (01-01-2009)“…Background Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARI-, -I2/I', and -I3) nuclear receptors. In particular, PPARI- is…”
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