Search Results - "Samsoondar, Joshua P"

The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK[S] by Morrow, Nadya M., Burke, Amy C., Samsoondar, Joshua P., Seigel, Kyle E., Wang, Andrew, Telford, Dawn E., Sutherland, Brian G., O'Dwyer, Conor, Steinberg, Gregory R., Fullerton, Morgan D., Huff, Murray W.

“…Obesity, dyslipidemia, and insulin resistance, the increasingly common metabolic syndrome, are risk factors for CVD and type 2 diabetes that warrant novel…”
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Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr−/− Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid by Samsoondar, Joshua P, Burke, Amy C, Sutherland, Brian G, Telford, Dawn E, Sawyez, Cynthia G, Edwards, Jane Y, Pinkosky, Stephen L, Newton, Roger S, Huff, Murray W

“…OBJECTIVE—Bempedoic acid (ETC-1002, 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid) is a novel low-density lipoprotein cholesterol–lowering compound. In…”
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Digital Quantification of Tumor Cellularity as a Novel Prognostic Feature of Non–Small Cell Lung Carcinoma by Lin, Sherman, Samsoondar, Joshua P., Bandari, Ela, Keow, Samantha, Bikash, Binit, Tan, Djarren, Martinez-Acevedo, Jacobo, Loggie, John, Pham, Michelle, Wu, Nina J., Misra, Tanya, Lam, Victor H.K., Sansano, Irene, Cecchini, Matthew J.

“…Non–small cell lung carcinoma is currently staged based on the size and involvement of other structures. Tumor size may be a surrogate measure of the total…”
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Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation by Fifield, Bre-Anne, Talia, John, Stoyanovich, Carlee, Elliott, Mitchell J, Bakht, Martin K, Basilious, Amy, Samsoondar, Joshua P, Curtis, Madison, Stringer, Keith F, Porter, Lisa A

“…Abstract Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. A variety of factors can contribute to the onset of…”
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Abstract 14653: Prevention of Diet-induced Metabolic Dysregulation, Inflammation and Atherosclerosis in Ldlr-/- Mice by Treatment With the ACL Inhibitor ETC-1002 by Samsoondar, Joshua P, Sutherland, Brian G, Telford, Dawn E, Sawyez, Cynthia G, Edwards, Jane Y, Filippov, Sergey, Pinkosky, Stephen L, Newton, Roger S, Huff, Murray W

“…ETC-1002 (8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid) is a novel LDL cholesterol-lowering compound. Preclinical studies revealed that ETC-1002…”
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Abstract 244: The Flavonoids Naringenin and Nobiletin Stimulate the AMPKinase Pathway in Primary Mouse Hepatocytes by Samsoondar, Joshua P, Bojic, Lazar A, Sutherland, Brian G, Steinberg, Gregory R, Edwards, Jane Y, Telford, Dawn E, Huff, Murray W

“…Abstract only Dyslipidemia associated with insulin resistance and obesity are core features of the metabolic syndrome and type 2 diabetes, which contribute…”
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Prevention of Murine Atherosclerosis with Bempedoic Acid by Samsoondar, Joshua P

“…Bempedoic acid (BA) is a novel LDL cholesterol-lowering compound. Preclinical studies revealed that BA inhibits hepatic cholesterol and fatty acid synthesis…”
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