Search Results - "Samson, T."

MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer by Meng, Fanyin, Henson, Roger, Wehbe–Janek, Hania, Ghoshal, Kalpana, Jacob, Samson T, Patel, Tushar

“…Background & Aims: microRNAs (miRNAs) are short noncoding RNAs that regulate gene expression negatively. Although a role for aberrant miRNA expression in…”
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Solar Activity Dependence of Traveling Ionospheric Disturbance Amplitudes Using a Rapid‐Run Ionosonde in High Latitudes by Moges, Samson T., Kozlovsky, Alexander, Sherstyukov, Ruslan O., Ulich, Thomas

“…We investigated the amplitude of medium scale traveling ionospheric disturbances (MSTIDs, with periods 25–100 min) and their dependence on the solar activity…”
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Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver by Hsu, Shu-Hao, Wang, Bo, Kota, Janaiah, Yu, Jianhua, Costinean, Stefan, Kutay, Huban, Yu, Lianbo, Bai, Shoumei, La Perle, Krista, Chivukula, Raghu R, Mao, Hsiaoyin, Wei, Min, Clark, K Reed, Mendell, Jerry R, Caligiuri, Michael A, Jacob, Samson T, Mendell, Joshua T, Ghoshal, Kalpana

“…miR-122, an abundant liver-specific microRNA (miRNA), regulates cholesterol metabolism and promotes hepatitis C virus (HCV) replication. Reduced miR-122…”
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Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating Glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha by Wang, Bo, Hsu, Shu-Hao, Frankel, Wendy, Ghoshal, Kalpana, Jacob, Samson T.

“…Considerable effort has been made in elucidating the mechanism and functional significance of high levels of aerobic glycolysis in cancer cells, commonly…”
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The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer by Barajas, Juan M., Reyes, Ryan, Guerrero, Maria J., Jacob, Samson T., Motiwala, Tasneem, Ghoshal, Kalpana

“…Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. Thus, a better understanding of molecular aberrations involved…”
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Quantifying the impact of Wolbachia releases on dengue infection in Townsville, Australia by Ogunlade, Samson T., Adekunle, Adeshina I., Meehan, Michael T., McBryde, Emma S.

“…From October 2014 to February 2019, local authorities in Townsville, North Queensland, Australia continually introduced Wolbachia -infected mosquitoes to…”
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Statistics of Traveling Ionospheric Disturbances at High Latitudes Using a Rapid‐Run Ionosonde by Moges, Samson T., Sherstyukov, Ruslan O., Kozlovsky, Alexander, Ulich, Thomas, Lester, Mark

“…The potential of deep learning for the investigation of medium scale traveling ionospheric disturbances (MSTIDs) has been exploited through the Sodankylä…”
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Downregulation of miR-122 in the rodent and human hepatocellular carcinomas by Kutay, Huban, Bai, Shoumei, Datta, Jharna, Motiwala, Tasneem, Pogribny, Igor, Frankel, Wendy, Jacob, Samson T., Ghoshal, Kalpana

“…MicroRNAs (miRs) are conserved small non‐coding RNAs that negatively regulate gene expression. The miR profiles are markedly altered in cancers and some of…”
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Cationic lipid nanoparticles for therapeutic delivery of siRNA and miRNA to murine liver tumor by Hsu, Shu-hao, PhD, Yu, Bo, PhD, Wang, Xinmei, PhD, Lu, Yuanzhi, PhD, Schmidt, Carl R., MD, Lee, Robert J., PhD, Lee, L. James, PhD, Jacob, Samson T., PhD, Ghoshal, Kalpana, PhD

“…Abstract miR-122, a liver-specific tumor suppressor microRNA, is frequently down-regulated in hepatocellular carcinoma (HCC). LNP-DP1, a cationic lipid…”
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Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model by Teng, Kun-Yu, Han, Jianfeng, Zhang, Xiaoli, Hsu, Shu-Hao, He, Shun, Wani, Nissar A, Barajas, Juan M, Snyder, Linda A, Frankel, Wendy L, Caligiuri, Michael A, Jacob, Samson T, Yu, Jianhua, Ghoshal, Kalpana

“…Hepatocellular carcinoma, a deadly disease, commonly arises in the setting of chronic inflammation. C-C motif chemokine ligand 2 (CCL2/MCP1), a chemokine that…”
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Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice by Wang, Bo, Majumder, Sarmila, Nuovo, Gerard, Kutay, Huban, Volinia, Stefano, Patel, Tushar, Schmittgen, Thomas D., Croce, Carlo, Ghoshal, Kalpana, Jacob, Samson T.

“…MicroRNAs (miRs) are conserved, small (20‐25 nucleotide) noncoding RNAs that negatively regulate expression of messenger RNAs (mRNAs) at the…”
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Reciprocal regulation of microRNA‐122 and c‐Myc in hepatocellular cancer: Role of E2F1 and transcription factor dimerization partner 2 by Wang, Bo, Hsu, Shu‐hao, Wang, Xinmei, Kutay, Huban, Bid, Hemant Kumar, Yu, Jianhua, Ganju, Ramesh K., Jacob, Samson T., Yuneva, Mariia, Ghoshal, Kalpana

“…c‐Myc is a well‐known oncogene frequently up‐regulated in different malignancies, whereas liver‐specific microRNA (miR)‐122, a bona fide tumor suppressor, is…”
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Down-regulation of Micro-RNA-1 (miR-1) in Lung Cancer: Suppression of Tumorigenic Property of Lung Cancer Cells and Their Sensitization to Doxorubicin-Induced Apoptosis by miR-1 by Nasser, Mohd W., Datta, Jharna, Nuovo, Gerard, Kutay, Huban, Motiwala, Tasneem, Majumder, Sarmila, Wang, Bo, Suster, Saul, Jacob, Samson T., Ghoshal, Kalpana

“…Micro-RNAs are ∼21–25-nucleotide-long noncoding RNAs that regulate gene expression primarily at the post-transcriptional level in animals. Here, we report that…”
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A Systematic Review of Mathematical Models of Dengue Transmission and Vector Control: 2010-2020 by Ogunlade, Samson T, Meehan, Michael T, Adekunle, Adeshina I, McBryde, Emma S

“…Vector control methods are considered effective in averting dengue transmission. However, several factors may modify their impact. Of these controls, chemical…”
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Modelling the ecological dynamics of mosquito populations with multiple co-circulating Wolbachia strains by Ogunlade, Samson T., Adekunle, Adeshina I., McBryde, Emma S., Meehan, Michael T.

“…Wolbachia intracellular bacteria successfully reduce the transmissibility of arthropod-borne viruses (arboviruses) when introduced into virus-carrying vectors…”
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Retraction: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes by Majumder, Sarmila, Roy, Satavisha, Kaffenberger, Thomas, Wang, Bo, Costinean, Stefan, Frankel, Wendy, Bratasz, Anna, Kuppusamy, Periannan, Hai, Tsonwin, Ghoshal, Kalpana, Jacob, Samson T

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Retraction: Physical and Functional Interaction of DNA Methyltransferase 3A with Mbd3 and Brg1 in Mouse Lymphosarcoma Cells by Datta, Jhrana, Majumder, Sarmila, Bai, Shoumei, Ghoshal, Kalpana, Kutay, Huban, Smith, David Spencer, Crabb, John W, Jacob, Samson T

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Anti-microRNA-222 (Anti-miR-222) and -181B Suppress Growth of Tamoxifen-resistant Xenografts in Mouse by Targeting TIMP3 Protein and Modulating Mitogenic Signal by Lu, Yuanzhi, Roy, Satavisha, Nuovo, Gerard, Ramaswamy, Bhuvaneswari, Miller, Tyler, Shapiro, Charles, Jacob, Samson T., Majumder, Sarmila

“…We have shown earlier that miR-221 and -222 are up-regulated in tamoxifen-resistant MCF-7 (OHTR) cells and Her2-positive human breast tumors when compared with…”
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Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells by Bai, Shoumei, Ghoshal, Kalpana, Jacob, Samson T

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Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations by Wang, Xinmei, Yu, Bo, Ren, Wei, Mo, Xiaokui, Zhou, Chenguang, He, Hongyan, Jia, HuLiang, Wang, Lu, Jacob, Samson T., Lee, Robert J., Ghoshal, Kalpana, Lee, L. James

“…Many cationic lipids have been developed for lipid-based nanoparticles (LNPs) for delivery of siRNA and microRNA (miRNA). However, less attention has been paid…”
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