Search Results - "Samson, Shiela C."
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1
ERK signaling for cell migration and invasion
Published in Frontiers in molecular biosciences (03-10-2022)“…The RAS - Extracellular signal-regulated kinase (RAS-ERK) pathway plays a conserved role in promoting cell migration and invasion. Growth factors, adhesion,…”
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2
3-OST-7 regulates BMP-dependent cardiac contraction
Published in PLoS biology (01-12-2013)“…The 3-O-sulfotransferase (3-OST) family catalyzes rare modifications of glycosaminoglycan chains on heparan sulfate proteoglycans, yet their biological…”
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Journal Article -
3
Sex reversal following deletion of a single distal enhancer of Sox9
Published in Science (American Association for the Advancement of Science) (29-06-2018)“…Cell fate decisions require appropriate regulation of key genes. , a direct target of SRY, is pivotal in mammalian sex determination. In vivo high-throughput…”
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4
NKX2-1 controls lung cancer progression by inducing DUSP6 to dampen ERK activity
Published in Oncogene (05-01-2022)“…The RAS→RAF→MEK→ERK pathway is hyperactivated in the majority of human lung adenocarcinoma (LUAD). However, the initial activating mutations induce homeostatic…”
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5
Nascent adhesions shorten the period of lamellipodium protrusion through the Brownian ratchet mechanism
Published in Molecular biology of the cell (01-11-2023)“…Directional cell migration is driven by the conversion of oscillating edge motion into lasting periods of leading edge protrusion. Actin polymerization against…”
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6
p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration
Published in The Journal of biological chemistry (12-07-2019)“…Cell migration is essential to embryonic development, wound healing, and cancer cell dissemination. Cells move via leading-edge protrusion, substrate adhesion,…”
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7
Nonthreaded Isomers of Sungsanpin and Ulleungdin Lasso Peptides Inhibit H1299 Cancer Cell Migration
Published in ACS chemical biology (19-01-2024)“…Lasso peptides are a structurally distinct class of biologically active natural products defined by their short sequences with impressively interlocked…”
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8
Microcionamides A and B, Bioactive Peptides from the Philippine Sponge Clathria (Thalysias) abietina
Published in Journal of organic chemistry (11-06-2004)“…Microcionamides A (1) and B (2) have been isolated from the Philippine marine sponge Clathria (Thalysias) abietina. These new linear peptides are cyclized via…”
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9
Sex reversal following deletion of a single far upstream enhancer of Sox9
Published in Science (American Association for the Advancement of Science) (14-06-2018)“…Cell fate decisions require appropriate regulation of key genes. Sox9 , a direct target of SRY, is pivotal in mammalian sex determination. In vivo…”
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Journal Article -
10
3-OST-7 Regulates BMP-Dependent Cardiac Contraction: e1001727
Published in PLoS biology (01-12-2013)“…The 3-O-sulfotransferase (3-OST) family catalyzes rare modifications of glycosaminoglycan chains on heparan sulfate proteoglycans, yet their biological…”
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Journal Article -
11
3-O-sulfotransferase is required for cardiac development and physiology in zebrafish
Published in Developmental biology (15-07-2008)Get full text
Journal Article -
12
3-ost-7 regulates cardiac function and development in zebrafish
Published 01-01-2011“…Heparan sulfate proteoglycans (HSPGs) are biologically relevant molecules composed of core proteins and glycosaminoglycan (GAG) chains. The location of HSPGs,…”
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Dissertation