Search Results - "Samsel, Jakob"
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Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIVAD8-EO infection
Published in Nature communications (29-08-2024)“…Anti-HIV-1 broadly neutralizing antibodies (bNAbs) have the dual potential of mediating virus neutralization and antiviral effector functions through their Fab…”
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Application of B cell immortalization for the isolation of antibodies and B cell clones from vaccine and infection settings
Published in Frontiers in immunology (13-12-2022)“…The isolation and characterization of neutralizing antibodies from infection and vaccine settings informs future vaccine design, and methodologies that…”
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Rhesus macaque Bcl-6/Bcl-xL B cell immortalization: Discovery of HIV-1 neutralizing antibodies from lymph node
Published in Journal of immunological methods (01-05-2023)“…Many HIV-1 vaccines are designed to elicit neutralizing antibodies, and pre-clinical testing is often carried out in rhesus macaques (RMs). We have therefore…”
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Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fcγ receptors during acute SHIV AD8-EO infection
Published in Nature communications (29-08-2024)“…Anti-HIV-1 broadly neutralizing antibodies (bNAbs) have the dual potential of mediating virus neutralization and antiviral effector functions through their Fab…”
Get full text
Journal Article -
5
Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site
Published in Science immunology (30-08-2024)“…Eliciting potent and broadly neutralizing antibodies (bnAbs) is a major goal in HIV-1 vaccine development. Here, we describe how germline-targeting immunogen…”
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