Search Results - "Samraj, Ajoy K."

Loss of Caspase-9 Provides Genetic Evidence for the Type I/II Concept of CD95-mediated Apoptosis by Samraj, Ajoy K., Keil, Eric, Ueffing, Nana, Schulze-Osthoff, Klaus, Schmitz, Ingo

“…The death receptor CD95 triggers apoptosis upon formation of a death-inducing signaling complex and the activation of caspase-8. Two types of CD95-mediated…”
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Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization by Samraj, Ajoy K, Sohn, Dennis, Schulze-Osthoff, Klaus, Schmitz, Ingo

“…Caspase-9 plays an important role in apoptosis induced by genotoxic stress. Irradiation and anticancer drugs trigger mitochondrial outer membrane…”
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Role of Unphosphorylated Transcription Factor STAT3 in Late Cerebral Ischemia after Subarachnoid Hemorrhage by Samraj, Ajoy K, Müller, Anne H, Grell, Anne-Sofie, Edvinsson, Lars

“…Molecular mechanisms behind increased cerebral vasospasm and local inflammation in late cerebral ischemia after subarachnoid hemorrhage (SAH) are poorly…”
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The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells by Stroh, Christopher, Cassens, Uwe, Samraj, Ajoy K., Sibrowski, Walter, Schulze‐Osthoff, Klaus, Los, Marek

“…ABSTRACT Cryopreserved cells and tissues are increasingly used for stem cell transplantation and tissue engineering. However, their freezing, storage, and…”
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Differentiation of mouse embryonic stem cells into cardiomyocytes via the hanging-drop and mass culture methods by Fuegemann, Christopher J, Samraj, Ajoy K, Walsh, Stuart, Fleischmann, Bernd K, Jovinge, Stefan, Breitbach, Martin

“…Herein, we describe two protocols for the in vitro differentiation of mouse embryonic stem cells (mESCs) into cardiomyocytes. mESCs are pluripotent and can be…”
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Viral modulation of cell death by inhibition of caspases by Cassens, Uwe, Lewinski, Grzegorz, Samraj, Ajoy K, von Bernuth, Horst, Baust, Heinrich, Khazaie, Khashayarsha, Los, Marek

“…Caspases are key effectors of the apoptotic process. Some of them play important roles in the immune system, being involved in the proteolytic maturation of…”
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