Search Results - "Samra, Yara A."

Turkish coffee has an antitumor effect on breast cancer cells in vitro and in vivo by Amin, Mohamed N, Abdelmohsen, Usama Ramadan, Samra, Yara A

“…Breast cancer is the most diagnosed cancer in women. Its pathogenesis includes several pathways in cancer proliferation, apoptosis, and metastasis. Some…”
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Homocysteine Induces Inflammation in Retina and Brain by Elsherbiny, Nehal M, Sharma, Isha, Kira, Dina, Alhusban, Suhib, Samra, Yara A, Jadeja, Ravirajsinh, Martin, Pamela, Al-Shabrawey, Mohamed, Tawfik, Amany

“…Homocysteine (Hcy) is an amino acid that requires vitamins B and folic acid for its metabolism. Vitamins B and folic acid deficiencies lead to…”
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Warburg Effect as a Novel Mechanism for Homocysteine-Induced Features of Age-Related Macular Degeneration by Samra, Yara A, Zaidi, Yusra, Rajpurohit, Pragya, Raghavan, Raju, Cai, Lun, Kaddour-Djebbar, Ismail, Tawfik, Amany

“…Age-related macular degeneration (AMD) is a major cause of blindness. Recent studies have reported impaired glycolysis in AMD patients with a high…”
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Cardio-protective impact of gabapentin against doxorubicin-induced myocardial toxicity in rats; emphasis on modulation of inflammatory-apoptotic signaling by Samra, Yara A., Amin, Mohamed N., Said, Eman

“…•Gabapentin revealed a cardio-protective impact against doxorubicin-induced myocardial injury.•Gabapentin improved the heart rate, ST segment elevation, QRS…”
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Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction by Tawfik, Amany, Samra, Yara A, Elsherbiny, Nehal M, Al-Shabrawey, Mohamed

“…Elevated plasma homocysteine (Hcy) level, known as hyperhomocysteinemia (HHcy) has been linked to different systemic and neurological diseases, well-known as a…”
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Implication of N -Methyl-d-Aspartate Receptor in Homocysteine-Induced Age-Related Macular Degeneration by Samra, Yara A, Kira, Dina, Rajpurohit, Pragya, Mohamed, Riyaz, Owen, Leah A, Shakoor, Akbar, Kim, Ivana K, DeAngelis, Margaret M, Sheibani, Nader, Al-Shabrawey, Mohamed, Tawfik, Amany

“…Age-related macular degeneration (AMD) is a leading cause of vision loss. Elevated homocysteine (Hcy) (Hyperhomocysteinemia) (HHcy) has been reported in AMD…”
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Cinnamaldehyde Relieves Induced Hepatocellular Carcinoma in Rat Model via Targeting Wnt/β-Catenin Pathway by Abd El Salam, Al Shaima G., Samra, Yara A., El-Shishtawy, Mamdouh M.

“…Cinnamaldehyde (CA) is a natural compound that has promising biological activity. The current study investigates the antitumor activity of CA in thioacetamide…”
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A novel role of nifuroxazide in attenuation of sepsis-associated acute lung and myocardial injuries; role of TLR4/NLPR3/IL-1β signaling interruption by Khodir, Ahmed E., Samra, Yara A., Said, Eman

“…Acute lung injury (ALI) and the subsequent multi-system organ failure is a serious health problem with devastating impacts on the health care systems. Indeed,…”
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Rutin and selenium nanoparticles protected against STZ-induced diabetic nephropathy in rats through downregulating Jak-2/Stat3 pathway and upregulating Nrf-2/HO-1 pathway by Zaghloul, Randa A., Abdelghany, Amr M., Samra, Yara A.

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P-Coumaric acid alleviates experimental diabetic nephropathy through modulation of Toll like receptor-4 in rats by Zabad, Omar M., Samra, Yara A., Eissa, Laila A.

“…Diabetic nephropathy (DN) is responsible for the occurrence of 30–47% of the incident cases of end-stage renal disease (ESRD) worldwide. DN is a chronic…”
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Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice by Helal, Manar G., Samra, Yara A.

“…Hepatotoxicity induced by acetaminophen (APAP)‐overdose is a major concern in clinical practice. In the present work, the detoxifying effect of irbesartan…”
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Cepharanthine and Piperine ameliorate diabetic nephropathy in rats: role of NF-κB and NLRP3 inflammasome by Samra, Yara A., Said, Heba S., Elsherbiny, Nehal M., Liou, Gregory I., El-Shishtawy, Mamdouh M., Eissa, Laila A.

“…Hyperglycemia leads to elevation of oxidative stress and proinflammatory cytokines which are the main causes of diabetic nephropathy (DN). NLRP3 inflammasome…”
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Polydatin gold nanoparticles potentiate antitumor effect of doxorubicin in Ehrlich ascites carcinoma‐bearing mice by Samra, Yara A., Abdelghany, Amr M., Zaghloul, Randa A.

“…Breast cancer is a leading cause of death. Anticancer treatment such as gold nanoparticles (AuNP) seems highly promising in this regard. Therefore, this study…”
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Hepatoprotective effect of allicin against acetaminophen‐induced liver injury: Role of inflammasome pathway, apoptosis, and liver regeneration by Samra, Yara A., Hamed, Mohamed F., El‐Sheakh, Ahmed R.

“…Acetaminophen (APAP) overdose leads to liver injury. NLRP3 inflammasome is a key player in APAP‐induced inflammation. Also, apoptosis and liver regeneration…”
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Adenosine Deaminase-2-Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA-146b-3p by Samra, Yara A, Saleh, Heba M, Hussein, Khaled A, Elsherbiny, Nehal M, Ibrahim, Ahmed S, Elmasry, Khaled, Fulzele, Sadanand, El-Shishtawy, Mamdouh M, Eissa, Laila A, Al-Shabrawey, Mohamed, Liou, Gregory I

“…We recently demonstrated that adenosine deaminase-2 (ADA2) contributes to diabetic retinopathy (DR) via up-regulating the production of inflammatory cytokines…”
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Syringic acid ameliorates experimental diabetic nephropathy in rats through its antiinflammatory, anti-oxidant and anti-fibrotic effects by suppressing Toll like receptor-4 pathway by Zabad, Omar M., Samra, Yara A., Eissa, Laila A.

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Cepharanthine improves glycemic status and slows the progression of renal and vascular injury in streptozotocin‐induced diabetic rats by Samra, Yara A., Katary, Mohamed A., El‐Shishtawy, Mamdouh M., Essa, Laila A., Baban, Babak, Elmarakby, Ahmed A.

“…We have previously demonstrated that Cepharanthine improves glycemic status and reduces renal injury in streptozotocin‐induced diabetic rats via antioxidant…”
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