Search Results - "Sampson, Robert D."

MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo by Fiedler, Lorna R., Chapman, Kathryn, Xie, Min, Maifoshie, Evie, Jenkins, Micaela, Golforoush, Pelin Arabacilar, Bellahcene, Mohamed, Noseda, Michela, Faust, Dörte, Jarvis, Ashley, Newton, Gary, Paiva, Marta Abreu, Harada, Mutsuo, Stuckey, Daniel J., Song, Weihua, Habib, Josef, Narasimhan, Priyanka, Aqil, Rehan, Sanmugalingam, Devika, Yan, Robert, Pavanello, Lorenzo, Sano, Motoaki, Wang, Sam C., Sampson, Robert D., Kanayaganam, Sunthar, Taffet, George E., Michael, Lloyd H., Entman, Mark L., Tan, Tse-Hua, Harding, Sian E., Low, Caroline M.R., Tralau-Stewart, Catherine, Perrior, Trevor, Schneider, Michael D.

“…Heart disease is a paramount cause of global death and disability. Although cardiomyocyte death plays a causal role and its suppression would be logical, no…”
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Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors by Gonzalez-Cordero, Anai, Kruczek, Kamil, Naeem, Arifa, Fernando, Milan, Kloc, Magdalena, Ribeiro, Joana, Goh, Debbie, Duran, Yanai, Blackford, Samuel J.I., Abelleira-Hervas, Laura, Sampson, Robert D., Shum, Ian O., Branch, Matthew J., Gardner, Peter J., Sowden, Jane C., Bainbridge, James W.B., Smith, Alexander J., West, Emma L., Pearson, Rachael A., Ali, Robin R.

“…Transplantation of rod photoreceptors, derived either from neonatal retinae or pluripotent stem cells (PSCs), can restore rod-mediated visual function in…”
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Use of bioreactors for culturing human retinal organoids improves photoreceptor yields by Ovando-Roche, Patrick, West, Emma L, Branch, Matthew J, Sampson, Robert D, Fernando, Milan, Munro, Peter, Georgiadis, Anastasios, Rizzi, Matteo, Kloc, Magdalena, Naeem, Arifa, Ribeiro, Joana, Smith, Alexander J, Gonzalez-Cordero, Anai, Ali, Robin R

“…The use of human pluripotent stem cell-derived retinal cells for cell therapy strategies and disease modelling relies on the ability to obtain healthy and…”
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The HSP70 co-chaperone DNAJC14 targets misfolded pendrin for unconventional protein secretion by Jung, Jinsei, Kim, Jiyoon, Roh, Shin Hye, Jun, Ikhyun, Sampson, Robert D., Gee, Heon Yung, Choi, Jae Young, Lee, Min Goo

“…Mutations in SLC26A4 , which encodes pendrin, are responsible for hearing loss with an enlarged vestibular aqueduct and Pendred syndrome. The most prevalent…”
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Activation of podocyte Notch mediates early Wt1 glomerulopathy by Asfahani, Rowan I, Tahoun, Mona M, Miller-Hodges, Eve V, Bellerby, Jack, Virasami, Alex K, Sampson, Robert D, Moulding, Dale, Sebire, Neil J, Hohenstein, Peter, Scambler, Peter J, Waters, Aoife M

“…The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations…”
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Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner by Waldron, Paul V., Di Marco, Fabiana, Kruczek, Kamil, Ribeiro, Joana, Graca, Anna B., Hippert, Claire, Aghaizu, Nozie D., Kalargyrou, Aikaterini A., Barber, Amanda C., Grimaldi, Giulia, Duran, Yanai, Blackford, Samuel J.I., Kloc, Magdalena, Goh, Debbie, Zabala Aldunate, Eduardo, Sampson, Robert D., Bainbridge, James W.B., Smith, Alexander J., Gonzalez-Cordero, Anai, Sowden, Jane C., Ali, Robin R., Pearson, Rachael A.

“…Human vision relies heavily upon cone photoreceptors, and their loss results in permanent visual impairment. Transplantation of healthy photoreceptors can…”
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Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration by Kruczek, Kamil, Gonzalez-Cordero, Anai, Goh, Debbie, Naeem, Arifa, Jonikas, Mindaugas, Blackford, Samuel J.I., Kloc, Magdalena, Duran, Yanai, Georgiadis, Anastasios, Sampson, Robert D., Maswood, Ryea N., Smith, Alexander J., Decembrini, Sarah, Arsenijevic, Yvan, Sowden, Jane C., Pearson, Rachael A., West, Emma L., Ali, Robin R.

“…The loss of cone photoreceptors that mediate daylight vision represents a leading cause of blindness, for which cell replacement by transplantation offers a…”
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Flow cytometric analysis of inflammatory and resident myeloid populations in mouse ocular inflammatory models by Liyanage, Sidath E., Gardner, Peter J., Ribeiro, Joana, Cristante, Enrico, Sampson, Robert D., Luhmann, Ulrich F.O., Ali, Robin R., Bainbridge, James W.

“…Myeloid cells make a pivotal contribution to tissue homeostasis during inflammation. Both tissue-specific resident populations and infiltrating myeloid cells…”
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Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT by Gilbert, Rose M, Zhang, Xiaozhe, Sampson, Robert D, Ehrenstein, Michael R, Nguyen, Dao X, Chaudhry, Mahid, Mein, Charles, Mahmud, Nadiya, Galatowicz, Grazyna, Tomkins-Netzer, Oren, Calder, Virginia L, Lightman, Sue

“…Non-infectious uveitis can cause chronic relapsing and remitting ocular inflammation, which may require high dose systemic immunosuppression to prevent severe…”
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PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection by Pollock, Katrina M, Montamat-Sicotte, Damien J, Grass, Lisa, Cooke, Graham S, Kapembwa, Moses S, Kon, Onn M, Sampson, Robert D, Taylor, Graham P, Lalvani, Ajit

“…HIV co-infection is an important risk factor for tuberculosis (TB) providing a powerful model in which to dissect out defective, protective and dysfunctional…”
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MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo by Fiedler, Lorna R., Chapman, Kathryn, Xie, Min, Maifoshie, Evie, Jenkins, Micaela, Golforoush, Pelin Arabacilar, Bellahcene, Mohamed, Noseda, Michela, Faust, Dörte, Jarvis, Ashley, Newton, Gary, Paiva, Marta Abreu, Harada, Mutsuo, Stuckey, Daniel J., Song, Weihua, Habib, Josef, Narasimhan, Priyanka, Aqil, Rehan, Sanmugalingam, Devika, Yan, Robert, Pavanello, Lorenzo, Sano, Motoaki, Wang, Sam C., Sampson, Robert D., Kanayaganam, Sunthar, Taffet, George E., Michael, Lloyd H., Entman, Mark L., Tan, Tse-Hua, Harding, Sian E., Low, Caroline M.R., Tralau-Stewart, Catherine, Perrior, Trevor, Schneider, Michael D.

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Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction by Rosenthal, Nadia, Schneider, Michael D., Sattler, Susanne, Sampson, Robert D., Gallego-Colon, Enrique, Tonkin, Joanne

“…Strategies to limit damage and improve repair after myocardial infarct remain a major therapeutic goal in cardiology. Our previous studies have shown that…”
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Fields of Battle: The Problem of Base Ball Playing Space in Post-Civil War Illinois by Sampson, Robert D.

“…In 1865, he was one of the organizers of the Capital Railway Company, which operated a horse railway from the center of town to the western edge.Besides…”
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Insulin-like growth factor-1 induces regulatory T cell-mediated suppression of allergic contact dermatitis in mice by Johannesson, Bjarki, Sattler, Susanne, Semenova, Ekaterina, Pastore, Saveria, Kennedy-Lydon, Teresa M, Sampson, Robert D, Schneider, Michael D, Rosenthal, Nadia, Bilbao, Daniel

“…Allergic contact dermatitis (ACD) is triggered by an aberrant hyperinflammatory immune response to innocuous chemical compounds and ranks as the world's most…”
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Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization by Tonkin, Joanne, Temmerman, Lieve, Sampson, Robert D, Gallego-Colon, Enrique, Barberi, Laura, Bilbao, Daniel, Schneider, Michael D, Musarò, Antonio, Rosenthal, Nadia

“…Insulin-like growth factor 1 (IGF-1) is a potent enhancer of tissue regeneration, and its overexpression in muscle injury leads to hastened resolution of the…”
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Interview with James R. Barrett by Sampson, Robert D.

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Interview with Mark DePue by Sampson, Robert D.

“…In early 2006, I was working as a civilian contractor at the National Guard Bureau headquarters in Arlington, Virginia, when I received a letter from…”
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Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance by Tung, Kenneth S K, Harakal, Jessica, Qiao, Hui, Rival, Claudia, Li, Jonathan C H, Paul, Alberta G A, Wheeler, Karen, Pramoonjago, Patcharin, Grafer, Constance M, Sun, Wei, Sampson, Robert D, Wong, Elissa W P, Reddi, Prabhakara P, Deshmukh, Umesh S, Hardy, Daniel M, Tang, Huanghui, Cheng, C Yan, Goldberg, Erwin

“…Autoimmune responses to meiotic germ cell antigens (MGCA) that are expressed on sperm and testis occur in human infertility and after vasectomy. Many MGCA are…”
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T-Cell Immunophenotyping Distinguishes Active From Latent Tuberculosis by Pollock, Katrina M., Whitworth, Hilary S., Montamat-Sicotte, Damien J., Grass, Lisa, Cooke, Graham S., Kapembwa, Moses S., Kon, Onn M., Sampson, Robert D., Taylor, Graham P., Lalvani, Ajit

“…Background. Changes in the phenotype and function of Mycobacterium tuberculosis (M. tuberculosis)-specific CD4⁺ and CD8⁺ T-cell subsets in response to stage of…”
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Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia by Villacampa, Pilar, Liyanage, Sidath E., Klaska, Izabela P., Cristante, Enrico, Menger, Katja E., Sampson, Robert D., Barlow, Maeve, Abelleira-Hervas, Laura, Duran, Yanai, Smith, Alexander J., Ali, Robin R., Luhmann, Ulrich F. O., Bainbridge, James W. B.

“…The retinal vasculature is tightly organized in a structure that provides for the high metabolic demand of neurons while minimizing interference with incident…”
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