Search Results - "Sample, Ashley"

Mechanisms and prevention of UV‐induced melanoma by Sample, Ashley, He, Yu‐Ying

“…Summary Melanoma is the deadliest form of skin cancer and its incidence is rising, creating a costly and significant clinical problem. Exposure to ultraviolet…”
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Autophagy in UV Damage Response by Sample, Ashley, He, Yu‐Ying

“…UV radiation exposure from sunlight and artificial tanning beds is the major risk factor for the development of skin cancer and skin photoaging. UV‐induced…”
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Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation by Sample, Ashley, Zhao, Baozhong, Qiang, Lei, He, Yu-Ying

“…Skin cancer is the most common cancer, and exposure to ultraviolet (UV) radiation, namely UVA and UVB, is the major risk factor for skin cancer development…”
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The Autophagy Receptor Adaptor p62 is Up‐regulated by UVA Radiation in Melanocytes and in Melanoma Cells by Sample, Ashley, Zhao, Baozhong, Wu, Chunli, Qian, Steven, Shi, Xianglin, Aplin, Andrew, He, Yu‐Ying

“…UVA (315–400 nm) is the most abundant form of UV radiation in sunlight and indoor tanning beds. However, much remains to be understood about the regulation of…”
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Examining the Entrepreneurial Leadership Propensities of Extension Educators by Jeffers-Sample, Ashley, Mars, Matthew M, Rice, Amber H, Torres, Robert M

“…Innovation and entrepreneurship are integral to the development and vitality of contemporary communities and economies. Accordingly, entrepreneurial leadership…”
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NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance by Yang, Seungwon, Qiang, Lei, Sample, Ashley, Shah, Palak, He, Yu-Ying

“…Macroautophagy (hereafter autophagy) is a catabolic cellular self-eating process by which unwanted organelles or proteins are delivered to lysosomes for…”
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Autophagy positively regulates DNA damage recognition by nucleotide excision repair by Qiang, Lei, Zhao, Baozhong, Shah, Palak, Sample, Ashley, Yang, Seungwon, He, Yu-Ying

“…Macroautophagy (hereafter autophagy) is a cellular catabolic process that is essential for maintaining tissue homeostasis and regulating various normal and…”
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Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis by Qiang, Lei, Sample, Ashley, Shea, Christopher R., Soltani, Keyoumars, Macleod, Kay F., He, Yu-Ying

“…Macroautophagy (hereafter autophagy) is a cellular "self-eating" process that is implicated in many human cancers, where it can act to either promote or…”
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Epidermal SIRT1 regulates inflammation, cell migration, and wound healing by Qiang, Lei, Sample, Ashley, Liu, Han, Wu, Xiaoyang, He, Yu-Ying

“…Sirtuins (SIRT1-7) are NAD-dependent proteins with the enzymatic activity of deacetylases and ADP ribosyltransferases. SIRT1 is the proto member of the…”
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Abstract 4060: The role of p62-dependent regulation of COX-2 in UVA response and skin tumor progression by Sample, Ashley, Qiang, Lei, Zhao, Baozhong, He, Yu-Ying

“…Abstract Skin cancer is the most common type of cancer in the US, with an estimated 3.5 million cases diagnosed each year. Exposure to ultraviolet (UV)…”
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EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion by Misek, Sean A, Chen, Jian, Schroeder, Laura, Rattanasinchai, Chotirat, Sample, Ashley, Sarkaria, Jann N, Gallo, Kathleen A

“…A hallmark of glioblastoma (GBM) tumors is their highly invasive behavior. Tumor dissemination into surrounding brain tissue is responsible for incomplete…”
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NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell ResistanceThis work was supported by National Institutes of Health Grants ES024373 and ES016936 from NIEHS (to Y.-Y. H.), American Cancer Society Grant RSG-13-078-01 (to Y.-Y. H.), University of Chicago Cancer Research Center Grant P30 CA014599, CTSA Grant UL1 TR000430, and the University of Chicago Friends of Dermatology Endowment Fund. The a by Yang, Seungwon, Qiang, Lei, Sample, Ashley, Shah, Palak, He, Yu-Ying

“…Macroautophagy (hereafter autophagy) is a catabolic cellular self-eating process by which unwanted organelles or proteins are delivered to lysosomes for…”
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Autophagy-Independent Regulation and Function of Autophagy Adaptor Protein P62 by Sample, Ashley

“…Skin cancer is the most common form of cancer, representing 40-50% of all cancers diagnosed. Exposure to ultraviolet (UV) radiation, namely UVA (315-400nm) and…”
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Dichotomous Roles for Hdac1 Haploinsufficiency in T Cell Acute Lymphoblastic Leukemia (T-ALL) by McConnell, Sean C., Denner, Darcy R., Sample, Ashley D., Restaino, Anthony C., Marin, Wilfredo, de Jong, Jill L.O.

“…Histone deacetylases (HDACs) are a family of enzymes that remove acetyl groups from histones and non-histone proteins, thereby modifying the structure of…”
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21ST Century Change Agents?: A Description of the Entrepreneurial Leadership Proclivities of Arizona Extension Educators by Jeffers-Sample, Ashley

“…The current knowledge-based economy demands a workforce equipped with the skills to advance innovation through entrepreneurial strategies (Powell & Snellman,…”
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