Search Results - "Samper, Sofía"
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New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages
Published in PLoS genetics (12-04-2018)“…The insertion Sequence IS6110, only present in the pathogens of the Mycobacterium tuberculosis Complex (MTBC), has been the gold-standard epidemiological…”
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Analysis of Mycobacterium africanum in the last 17 years in Aragon identifies a specific location of IS6110 in Lineage 6
Published in Scientific reports (14-05-2021)“…The purpose of this study was to increase our knowledge about Mycobacterium africanum and report the incidence and characteristics of tuberculosis (TB) due to…”
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Estimation of the mutation rate of Mycobacterium tuberculosis in cases with recurrent tuberculosis using whole genome sequencing
Published in Scientific reports (06-10-2022)“…The study of tuberculosis latency is problematic due to the difficulty of isolating the bacteria in the dormancy state. Despite this, several in vivo…”
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Hominin Dispersal and Settlement East of Huxley’s Line: The Role of Sea Level Changes, Island Size, and Subsistence Behavior
Published in Current anthropology (01-12-2017)“…The thousands of islands east of Huxley’s Line have never formed a single land mass or been connected to Sunda or Sahul. The earliest records of hominins in…”
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A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component
Published in Infection and immunity (01-08-2014)“…The ESX-1 secreted virulence factor ESAT-6 is one of the major and most well-studied virulence factors of Mycobacterium tuberculosis, given that its…”
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Analysis of the twenty-six largest outbreaks of tuberculosis in Aragon using whole-genome sequencing for surveillance purposes
Published in Scientific reports (05-11-2022)“…The incidence of tuberculosis in Aragon, Spain, is around ten cases per 100,000 inhabitants. Since 2004, a molecular surveillance protocol has been carried…”
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Fishing in life and death: Pleistocene fish-hooks from a burial context on Alor Island, Indonesia
Published in Antiquity (01-12-2017)“…Fish-hooks discovered among grave goods associated with an adult female burial at the Tron Bon Lei rockshelter on the island of Alor in Indonesia are the first…”
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Mapping IS6110 in high-copy number Mycobacterium tuberculosis strains shows specific insertion points in the Beijing genotype
Published in BMC genomics (25-06-2013)“…Mycobacterium tuberculosis Beijing strains are characterized by a large number of IS6110 copies, suggesting the potential implication of this element in the…”
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A Mycobacterium tuberculosis Beijing strain persists at high rates and extends its geographic boundaries 20 years after importation
Published in Scientific reports (18-03-2019)“…Transmission of Beijing Mycobacterium tuberculosis can be investigated based on genotypic analysis of clinical isolates. A Beijing strain began to spread on…”
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Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro–American genetic background confers optimal vaccine potential
Published in EBioMedicine (01-05-2020)“…Human tuberculosis (TB) is caused by a plethora of Mycobacterium tuberculosis complex (MTBC) strains belonging to seven phylogenetic branches. Lineages 2, 3…”
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Somewhere beyond the sea: Human cranial remains from the Lesser Sunda Islands (Alor Island, Indonesia) provide insights on Late Pleistocene peopling of Island Southeast Asia
Published in Journal of human evolution (01-09-2019)“…The migration of anatomically modern humans (AMH) from Africa to every inhabitable continent included their dispersal through Island Southeast Asia (ISEA) to…”
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Antimicrobial photodynamic activity of Rose Bengal, alone or in combination with Gentamicin, against planktonic and biofilm Staphylococcus aureus
Published in Photodiagnosis and photodynamic therapy (01-03-2018)“…•aPDT using Rose Bengal (RB) has a bactericidal effect against planktonic S. aureus.•In biofilm, bactericidal effect is achieved when gentamicin was used in…”
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The MtZ Strain: Molecular Characteristics and Outbreak Investigation of the Most Successful Mycobacterium tuberculosis Strain in Aragon Using Whole-Genome Sequencing
Published in Frontiers in cellular and infection microbiology (24-05-2022)“…Since 2004, a tuberculosis surveillance protocol has been carried out in Aragon, thereby managing to detect all tuberculosis outbreaks that take place in the…”
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Role of wild bird and rodents in the epidemiology of subclinical salmonellosis in finishing pigs
Published in Foodborne pathogens and disease (01-09-2014)“…Wild birds and rodents may play an important role in the dynamics of subclinical pig salmonellosis, either as the introducers of the bacteria into the farm or…”
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Rapid Identification of Lineage and Drug Resistance in Clinical Samples of Mycobacterium tuberculosis
Published in Microorganisms (Basel) (31-05-2023)“…is a slow-growing bacterium, which could delay its diagnosis and, therefore, promote the spread of the disease. Whole-genome sequencing allows us to obtain the…”
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Analysis of Mutations in Streptomycin-Resistant Strains Reveals a Simple and Reliable Genetic Marker for Identification of the Mycobacterium tuberculosis Beijing Genotype
Published in Journal of Clinical Microbiology (01-07-2013)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An essential role for phoP in Mycobacterium tuberculosis virulence
Published in Molecular microbiology (01-07-2001)“…Two‐component regulatory proteins function in bacteria as sensory and adaptive factors in response to a wide range of environmental stimuli. Some two‐component…”
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In-depth analysis of the genome sequence of a clinical, extensively drug-resistant Mycobacterium bovis strain
Published in Tuberculosis (Edinburgh, Scotland) (01-09-2016)“…Summary Although human-to-human transmission of Mycobacterium bovis strains and other members of the animal lineage of the tubercle bacilli is a rare event, an…”
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Deciphering the Tangible Spatio-Temporal Spread of a 25-Year Tuberculosis Outbreak Boosted by Social Determinants
Published in Microbiology spectrum (14-02-2023)“…Outbreak strains of Mycobacterium tuberculosis are promising candidates as targets in the search for intrinsic determinants of transmissibility, as they are…”
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