Search Results - "Sampedro, A."

Comprehensive splicing analysis of the alternatively spliced CHEK2 exons 8 and 10 reveals three enhancer/silencer‐rich regions and 38 spliceogenic variants by Sanoguera‐Miralles, Lara, Llinares‐Burguet, Inés, Bueno‐Martínez, Elena, Ramadane‐Morchadi, Lobna, Stuani, Cristiana, Valenzuela‐Palomo, Alberto, García‐Álvarez, Alicia, Pérez‐Segura, Pedro, Buratti, Emanuele, Hoya, Miguel, Velasco‐Sampedro, Eladio A

“…Splicing is controlled by a large set of regulatory elements (SREs) including splicing enhancers and silencers, which are involved in exon recognition…”
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Predictive value of body composition and core symptoms in schizophrenia for cardiorespiratory fitness: CORTEX-SP study by Tous-Espelosin, M., Iriarte Yoller, N., Pavón, C., Sanchez, P.M., Sampedro, A., Maldonado-Martín, S.

“…Introduction Cardiorespiratory fitness (CRF) can be directly measured and assessed by the cardiopulmonary exercise test (CPET) or estimated from different…”
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Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study by Rojo-Martínez, G., Valdés, S., Soriguer, F., Vendrell, J., Urrutia, I., Pérez, V., Ortega, E., Ocón, P., Montanya, E., Menéndez, E., Lago-Sampedro, A., González- Frutos, T., Gomis, R., Goday, A., García-Serrano, S., García-Escobar, E., Galán-García, J. L., Castell, C., Badía-Guillén, R., Aguilera-Venegas, G., Girbés, J., Gaztambide, S., Franch-Nadal, J., Delgado, E., Chaves, F. J., Castaño, L., Calle-Pascual, A.

“…Our aim was to determine the incidence of type 2 diabetes mellitus in a nation-wide population based cohort from Spain (di@bet.es study). The target was the…”
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Minigene‐based splicing analysis and ACMG/AMP‐based tentative classification of 56 ATM variants by Bueno‐Martínez, Elena, Sanoguera‐Miralles, Lara, Valenzuela‐Palomo, Alberto, Esteban‐Sánchez, Ada, Lorca, Víctor, Llinares‐Burguet, Inés, Allen, Jamie, García‐Álvarez, Alicia, Pérez‐Segura, Pedro, Durán, Mercedes, Easton, Douglas F, Devilee, Peter, Vreeswijk, Maaike PG, Hoya, Miguel, Velasco‐Sampedro, Eladio A

“…The ataxia telangiectasia‐mutated (ATM) protein is a major coordinator of the DNA damage response pathway. ATM loss‐of‐function variants are associated with…”
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Changes in thyroid function with age: results from the Pizarra population-based longitudinal study by Lago-Sampedro, A Ma, Gutiérrez-Repiso, C, Valdés, S, Maldonado, C, Colomo, N, Almaraz, M C, Rubio-Martín, E, Morcillo, S, Esteva, I, Ruiz de Adana, M S, Perez-Valero, V, Soriguer, F, Rojo-Martínez, G, García-Fuentes, E

“…Results of studies examining the influence of age on thyroid function and TSH levels, in the absence of thyroid disease, remain controversial. The aim of this…”
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Cost‐effectiveness analysis of dyevert™ Power XT in patients with chronic kidney disease undergoing percutaneous coronary intervention procedures in Spain by López‐Mínguez, Jose R., Martín de Francisco, A. L., Soler, M. J., Hernández, Felipe, Moreno, Raul, Pinar, Eduardo, Sampedro, A., Mareque, M., Oyagüez, I.

“…Objective To assess the efficiency of Dyevert™ Power XT compared to the standard clinical practice when used for percutaneous coronary interventions (PCI)…”
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Effect of Single Layer Centrifugation Porcicoll (70%, 80% and 90%) or supplementation with reduced glutathione, seminal plasma and bovine serum albumin on frozen-thawed boar sperm by Crespo-Félez, I., Castañeda-Sampedro, A., Sánchez, D.I., Fernández-Alegre, E., Álvarez-Rodríguez, M., Domínguez, J.C., Morrell, J.M., Martínez-Pastor, F.

“…•Single Layer Centrifugation in frozen-thawed boar sperm.•Porcicoll 80% selected high-quality boar sperm population.•Boar seminal plasma after thawing induce…”
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Fatty liver index as a predictor for type 2 diabetes in subjects with normoglycemia in a nationwide cohort study by García-Escobar, E., Valdés, S., Soriguer, F., Vendrell, J., Urrutia-Etxebarria, I. M., Maldonado-Araque, C., Ortega, E., Ocón, P., Montanya, E., Menéndez, E., Lago-Sampedro, A., González-Frutos, T., Gomis, R., Goday, A., García-Serrano, S., Galán-García, J. L., Castell, C., Bordiú, E., Badía, R., Aguilera-Venegas, G., Girbés, J., Gaztambide, S., Delgado, E., Chaves, F. J., Castaño, L., Calle-Pascual, A., Rojo-Martínez, G., Franch-Nadal, J.

“…Our aim was to evaluate whether fatty liver index (FLI) is associated with the risk of type 2 diabetes (T2DM) development within the Spanish adult population…”
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Maximum adenoma diameter, regardless of uni- or bilaterality, is a risk factor for autonomous cortisol secretion in adrenal incidentalomas by Araujo-Castro, M., Robles Lázaro, C., Parra Ramírez, P., García Centeno, R., Gracia Gimeno, P., Fernández-Ladreda, M. T., Sampedro Núñez, M. A., Marazuela, M., Escobar-Morreale, H. F., Valderrabano, P.

“…Purpose To evaluate differences between patients with unilateral and bilateral adrenal incidentalomas (AIs) in the prevalence of autonomous cortisol secretion…”
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Structural and functional alterations associated with deutan N94K and R330Q mutations of green cone opsin by Srinivasan, Sundaramoorthy, Fernández-Sampedro, Miguel A., Ramon, Eva, Garriga, Pere

“…Deuteranopia is an X-linked congenital dichromatic condition in which single point mutations in green cone opsin lead to defective non-functional cone…”
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Comparing RNA extraction methods to face the variations in RNA quality using two human biological matrices by Ortega-Pinazo, J., Pacheco-Rodríguez, M. J., Serrano-Castro, P. J., Martínez, B., Pinto-Medel, M. J., Gómez-Zumaquero, J. M., Lago-Sampedro, A., García-Díaz, B., Estivill-Torrús, Guillermo, Emilio Ferro Gallego, Pedro

“…Background Nucleic acids, RNA among them, are widely used in biomedicine and Biotechnology. Because of their susceptibility to degradation by RNases, the…”
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Human Blue Cone Opsin Regeneration Involves Secondary Retinal Binding with Analog Specificity by Srinivasan, Sundaramoorthy, Fernández-Sampedro, Miguel A., Morillo, Margarita, Ramon, Eva, Jiménez-Rosés, Mireia, Cordomí, Arnau, Garriga, Pere

“…Human color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein…”
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Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis by Lupiañez, C B, Martínez-Bueno, M, Sánchez-Maldonado, J M, Badiola, J, Cunha, C, Springer, J, Lackner, M, Segura-Catena, J, Canet, L M, Alcazar-Fuoli, L, López-Nevot, M A, Fianchi, L, Aguado, J M, Pagano, L, López-Fernández, E, Alarcón-Riquelme, M, Potenza, L, Gonçalves, S M, Luppi, M, Moratalla, L, Solano, C, Sampedro, A, González-Sierra, P, Cuenca-Estrella, M, Lagrou, K, Maertens, J A, Lass-Flörl, C, Einsele, H, Vazquez, L, Loeffler, J, Ríos-Tamayo, R, Carvalho, A, Jurado, M, Sainz, J

“…Invasive aspergillosis (IA) is a life-threatening infection that affects an increasing number of patients undergoing chemotherapy or allo-transplantation, and…”
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Long-term treatment with pegvisomant for acromegaly: a 10-year experience by Ramos-Leví, Ana M., Bernabeu, Ignacio, Álvarez-Escolá, Cristina, Aller, Javier, Lucas, Tomás, de Miguel, Paz, Rodríguez-Cañete, Leticia, Sampedro-Núñez, Miguel A., Halperin, Irene, Puig-Domingo, Manuel, Marazuela, Mónica

“…Summary Background Efficacy of the GH‐receptor antagonist pegvisomant (PEG) has differed between preclinical and observational studies mainly due to dose…”
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COVID-19 Lockdown and Changes of the Dietary Pattern and Physical Activity Habits in a Cohort of Patients with Type 2 Diabetes Mellitus by Ruiz-Roso, María Belén, Knott-Torcal, Carolina, Matilla-Escalante, Diana C, Garcimartín, Alba, Sampedro-Nuñez, Miguel A, Dávalos, Alberto, Marazuela, Mónica

“…The COVID-19 lockdown clearly affected the lifestyle of the population and entailed changes in their daily habits, which involved potential health…”
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Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution by Fernández-Sampedro, Miguel A., Invergo, Brandon M., Ramon, Eva, Bertranpetit, Jaume, Garriga, Pere

“…Visual rhodopsins are membrane proteins that function as light photoreceptors in the vertebrate retina. Specific amino acids have been positively selected in…”
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Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression by Unzu, C, Melero, I, Hervás-Stubbs, S, Sampedro, A, Mancheño, U, Morales-Kastresana, A, Serrano-Mendioroz, I, de Salamanca, R E, Benito, A, Fontanellas, A

“…Helper-dependent adenoviral (HDA) vectors constitute excellent gene therapy tools for metabolic liver diseases. We have previously shown that an HDA vector…”
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Seroprevalence of Leishmania infection among asymptomatic renal transplant recipients from southern Spain by Elmahallawy, E.K., Cuadros-Moronta, E., Liébana-Martos, M.C., Rodríguez-Granger, J.M., Sampedro-Martínez, A., Agil, A., Navarro-Mari, J.M., Bravo-Soto, J., Gutierrez-Fernández, J.

“…Background The aim of this article is to assess the seroprevalence of Leishmania infection among asymptomatic renal transplant recipients in a population in…”
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Hypophysitis following Treatment with Ustekinumab: Radiological and Pathological Findings by Ramos-Leví, Ana M, Gargallo, Manuel, Serrano-Somavilla, Ana, Sampedro-Núñez, Miguel A, Fraga, Javier, Marazuela, Monica

“…Ustekinumab is a human IgG1 monoclonal antibody that targets interleukin (IL)-12 and IL-23, which may be useful in the treatment of autoimmune conditions such…”
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Homing in on the specific phenotype(s) of central respiratory chemoreceptors by Richerson, G. B., Wang, W., Hodges, M. R., Dohle, C. I., Diez-Sampedro, A.

“…To some it may seem that we now know less about respiratory chemoreception than we did 20 years ago. Back then, it was widely accepted that the central…”
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