Search Results - "Sampaio, Raimunda Nonata"
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Comparison of cardiotoxicity between N-methyl-glucamine and miltefosine in the treatment of American cutaneous leishmaniasis
Published in Anais brasileiros de dermatología (01-07-2021)Get full text
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2
Leprosy detection rate in patients under immunosuppression for the treatment of dermatological, rheumatological, and gastroenterological diseases: a systematic review of the literature and meta-analysis
Published in BMC infectious diseases (13-04-2021)“…Recently developed immunosuppressive drugs, especially TNF antagonists, may enhance the risk of granulomatous infections, including leprosy. We aimed to…”
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Meglumine antimoniate was associated with a higher cure rate than liposomal amphotericin B in the treatment of American tegumentary leishmaniasis: A retrospective cohort study from a Leishmania braziliensis-endemic area
Published in Frontiers in cellular and infection microbiology (23-09-2022)“…Background Pentavalent antimonials (PAs) are the primary therapeutic option for American tegumentary leishmaniasis (ATL). However, the use of these drugs is…”
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Successful treatment of diffuse cutaneous leishmaniasis caused by Leishmania amazonensis
Published in Anais brasileiros de dermatología (01-09-2021)“…Diffuse cutaneous leishmaniasis is a rare universal disease associated with an inadequate host cell immune response, caused by different species: infantum,…”
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The Presence of Leishmania braziliensis DNA in the Nasal Mucosa of Cutaneous Leishmaniasis Patients and the Search for Possible Clinical and Immunological Patterns of Disease Progression: A Cross Sectional Study
Published in Frontiers in cellular and infection microbiology (14-10-2021)“…Leishmania braziliensis is the most important causal agent of American tegumentary leishmaniasis (ATL), and 3 to 5% of patients develop mucosal lesions. The…”
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A Pilot Randomized Clinical Trial: Oral Miltefosine and Pentavalent Antimonials Associated With Pentoxifylline for the Treatment of American Tegumentary Leishmaniasis
Published in Frontiers in cellular and infection microbiology (01-07-2021)“…Introduction American tegumentary leishmaniasis (ATL), which can present as either cutaneous (CL) or mucosal leishmaniasis (ML), is endemic in South America,…”
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PD-L1 May Mediate T-Cell Exhaustion in a Case of Early Diffuse Leishmaniasis Caused by Leishmania (L.) amazonensis
Published in Frontiers in immunology (11-05-2018)“…Diffuse cutaneous leishmaniasis (DCL) is a rare disease form associated with (L.) in South America. It represents the "anergic" pole of American Tegumentary…”
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Complementary exams in the diagnosis of American tegumentary leishmaniasis
Published in Anais brasileiros de dermatología (01-09-2014)“…The diagnosis of American Tegumentary Leishmaniasis is a difficult but essential task when considering the high toxicity profile of the drugs available. Since…”
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A retrospective cohort study of the effectiveness and adverse events of intralesional pentavalent antimonials in the treatment of cutaneous leishmaniasis
Published in International journal for parasitology -- drugs and drug resistance (01-12-2020)“…The standard therapy for American cutaneous leishmaniasis (ACL) is intravenous meglumine antimoniate (IV-MA). However, treatment interruptions due to adverse…”
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A comprehensive systematic review of leishmaniasis in patients undergoing drug-induced immunosuppression for the treatment of dermatological, rheumatological and gastroenterological diseases
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-01-2020)“…Immunosuppression is an important risk factor for leishmaniasis. We assessed the clinical profile, geographic distribution and prevalence of leishmaniasis in…”
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The accuracy of the Montenegro skin test for leishmaniasis in PCR-negative patients
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2020)“…As highly specific molecular biology-based techniques may not be sensitive enough for the diagnosis of American tegumentary leishmaniasis (ATL), clinicians…”
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American cutaneous leishmaniasis triggered by electrocoagulation
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2018)“…Cutaneous leishmaniasis is usually transmitted by infected phlebotomine sand fly bites that initiate local cutaneous lesions. Few reports in the literature…”
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Field validation of a Leishmania (Leishmania) mexicana exo-antigens ELISA for diagnosing tegumentary leishmaniasis in regions of Leishmania (Viannia) predominance
Published in The Brazilian journal of infectious diseases (01-05-2015)“…Several tests are performed to obtain better accuracy when diagnosing American tegumentary leishmaniasis (ATL). It is believed that antigens released via…”
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A randomized, open-label clinical trial comparing the long-term effects of miltefosine and meglumine antimoniate for mucosal leishmaniasis
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2019)“…The treatment of mucosal leishmaniasis (ML) is difficult due to the toxicity and route of administration of standard drugs. Miltefosine is an oral agent used…”
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The interference of polypharmacy and the importance of clinical pharmacy advice in the treatment of leprosy: a case-control study
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2020)“…INTRODUCTIONAlthough supervised doses are essential for reducing leprosy treatment failure, the impact of specific drug interactions has rarely been assessed…”
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Accuracy of mucocutaneous leishmaniasis diagnosis using polymerase chain reaction: systematic literature review and meta-analysis
Published in Memórias do Instituto Oswaldo Cruz (01-04-2015)“…The diagnosis of mucocutaneous leishmaniasis (MCL) is hampered by the absence of a gold standard. An accurate diagnosis is essential because of the high…”
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Miltefosine enhances phagocytosis but decreases nitric oxide production by peritoneal macrophages of C57BL/6 mice
Published in International immunopharmacology (01-05-2012)“…Miltefosine is an anticancer drug currently used to treat visceral and cutaneous leishmaniasis, also presents a broad-spectrum of fungicidal and antiamoebae…”
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Field Validation of SYBR Green- and TaqMan-Based Real-Time PCR Using Biopsy and Swab Samples To Diagnose American Tegumentary Leishmaniasis in an Area Where Leishmania (Viannia) braziliensis Is Endemic
Published in Journal of clinical microbiology (01-02-2017)“…The precise diagnosis of American tegumentary leishmaniasis (ATL) is an essential task due to the disease's associated morbidity. A noninvasive, extremely…”
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Effectiveness of miltefosine-pentoxifylline compared to miltefosine in the treatment of cutaneous leishmaniasis in C57Bl/6 mice
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-07-2014)“…The treatment of leishmaniasis ischallenging, given the difficulties in drug administration and resistance. Therefore, we chose to test the efficacy of…”
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No evidence for cardiotoxicity of miltefosine – Reply
Published in Anais brasileiros de dermatología (01-07-2022)Get full text
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