Search Results - "Sampaio, Claudio A M"
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The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition
Published in Biochemical journal (01-01-2005)“…Several IAP (inhibitor of apoptosis) proteins regulate cell fate decisions, and the X-linked IAP (XIAP) does so in part by inhibiting caspases, proteases that…”
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2
BmTI antigens induce a bovine protective immune response against Boophilus microplus tick
Published in International immunopharmacology (01-03-2002)“…Boophilus microplus trypsin inhibitors (BmTIs) present in larvae were preliminarily characterized as active proteins, approximately 10–18 kDa, by SDS-PAGE…”
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3
A proteinase inhibitor from Caesalpinia echinata (pau-brasil) seeds for plasma kallikrein, plasmin and factor XIIa
Published in Biological chemistry (01-11-2004)“…Caesalpinia echinata is a tree belonging to the Leguminosae family. The red color of the trunk, looking like burning wood ('brasa' in Portuguese), is the…”
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4
Purification, Characterization, and Amino Acid Sequence of a Serine Proteinase, PA-BJ, with Platelet-Aggregating Activity from the Venom of Bothrops jararaca
Published in Biochemistry (Easton) (30-05-1995)“…A platelet-aggregating enzyme, PA-BJ, was isolated from the venom of the snake Bothrops jararaca. PA-BJ in a concentration of 3.2 x 10(-8) M promoted 95%…”
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5
Glycosaminoglycans affect the action of human plasma kallikrein on kininogen hydrolysis and inflammation
Published in International immunopharmacology (01-12-2002)“…Human plasma kallikrein (huPK) is a serine proteinase involved in many biological processes including those of the kallikrein–kinin system. The action of huPK…”
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6
The complete amino acid sequence of a trypsin inhibitor from Bauhinia variegata var. candida seeds
Published in Journal of Protein Chemistry (01-11-1998)“…Trypsin inhibitors of two varieties of Bauhinia variegata seeds have been isolated and characterized. Bauhinia variegata candida trypsin inhibitor (BvcTI) and…”
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Purification and characterization of a kinin‐releasing and fibrinogen‐clotting serine proteinase (KN‐BJ) from the venom of Bothrops jararaca, and molecular cloning and sequence analysis of its cDNA
Published in European journal of biochemistry (01-02-1998)“…Two forms of a proteinase, KN‐BJ 1 and 2, were purified to homogeneity from the venom of Bothrops jararaca. In SDS/PAGE reduced KN‐BJ 1 and 2 migrated as…”
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8
A prothrombin activator from Bothrops erythromelas (jararaca-da-seca) snake venom: characterization and molecular cloning
Published in Biochemical journal (01-01-2003)“…A novel prothrombin activator enzyme, which we have named 'berythractivase', was isolated from Bothrops erythromelas (jararaca-da-seca) snake venom…”
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9
Kunitz-type Bauhinia bauhinioides inhibitors devoid of disulfide bridges: isolation of the cDNAs, heterologous expression and structural studies
Published in Biological chemistry (01-06-2005)“…Bauhinia bauhinoides cruzipain inhibitor (BbCI) and Bauhinia bauhinioides kallikrein inhibitor (BbKI) are cysteine and serine proteinase inhibitors…”
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10
Characterization of a Kunitz Trypsin Inhibitor with One Disulfide Bridge Purified from Swartzia pickellii
Published in Biochemical and biophysical research communications (01-03-2002)“…Swartzia pickellii is a Leguminosae that belongs to the Caesalpinioideae sub-family the Swartzia pickellii Trypsin Inhibitor (SWTI), a serine proteinase…”
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11
Cloning, expression and characterization of Bauhinia variegata trypsin inhibitor BvTI
Published in Biological chemistry (01-11-2005)“…A Bauhinia variegata trypsin inhibitor (BvTI) cDNA fragment was cloned into the pCANTAB5E phagemid. The clone pAS 1.1.3 presented a cDNA fragment of 733 bp,…”
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12
Vitamin E prevents cell death induced by mild oxidative stress in chicken skeletal muscle cells
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-07-2005)“…Apoptosis and necrosis are two forms of cell death that can occur in response to various agents and oxidative damage. In addition to necrosis, apoptosis…”
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13
Primary sequence determination of a Kunitz inhibitor isolated from Delonix regia seeds
Published in Phytochemistry (Oxford) (01-07-2001)“…A serine proteinase inhibitor was purified from Delonix regia seeds a Leguminosae tree of the Caesalpinioideae subfamily. The inhibitor named DrTI, inactivated…”
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14
Effect of plant Kunitz inhibitors from Bauhinia bauhinioides and Bauhinia rufa on pulmonary edema caused by activated neutrophils
Published in Biological chemistry (01-06-2003)“…Mediators released from polymorphonuclear neutrophils, in particular elastase, are known to induce acute edematous lung injury. In this study we show that the…”
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15
Evaluation of phage display system and leech-derived tryptase inhibitor as a tool for understanding the serine proteinase specificities
Published in Archives of biochemistry and biophysics (01-05-2004)“…A small combinatorial library of LDTI mutants (5.2 × 10 4) restricted to the P1–P4 ′ positions of the reactive site was displayed on the pCANTAB 5E phagemid,…”
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A Prothrombin Activator Serine Protease from the Lonomia obliqua Caterpillar Venom (Lopap) : Biochemical Characterization
Published in Thrombosis research (01-06-2001)“…Lonomia obliqua venom causes a severe consumptive coagulopathy, which can lead to a hemorrhagic syndrome. The crude bristles extract displays a procoagulant…”
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Plasma prekallikrein/kallikrein processing by lysosomal cysteine proteases
Published in Biological chemistry (01-11-2004)“…Plasma kallikrein plays a role in coagulation, fibrinolysis and inflammation. Cathepsins B and L participate in (patho)physiological processes such as peptide…”
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High molecular weight kininogen as substrate for cathepsin B
Published in Biological chemistry (01-06-2004)“…We investigated the influence of pH and divalent cations (Zn2+, Mg2+ and Ca2+) on high molecular weight kininogen processing by cathepsin B. At pH 6.3, high…”
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A new factor Xa inhibitor (lefaxin) from the Haementeria depressa leech
Published in Thrombosis and haemostasis (01-11-1999)“…The salivary complex of the leech Haementeria depressa produces potent anticoagulant components. Among them, a protein named lefaxin inhibits factor Xa (FXa)…”
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Action of Bauhinia bauhinioides synthetic peptides on serine proteinases
Published in Biochemical and biophysical research communications (07-11-2003)“…The kallikrein inhibitor found in Bauhinia bauhinioides seeds (BbKI) differs from classical Kunitz plant inhibitors in the lack of disulfide bridges in its…”
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