Search Results - "Samoylova, Olga"
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Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions
Published in The New England journal of medicine (06-06-2019)“…The combination of the BCL2 inhibitor venetoclax plus obinutuzumab was more effective in the treatment of older medically ill patients with untreated chronic…”
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Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions
Published in The New England journal of medicine (20-03-2014)“…Obinutuzumab, a glycoengineered anti-CD20 antibody with increased killing capacity, outperformed rituximab when used in combination with chlorambucil in…”
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Molecular Dynamics Simulations of Ion Transport in Carbon Nanotube Channels
Published in Journal of physical chemistry. C (29-01-2015)“…We present a computational modeling study examining ion transport dynamics of aqueous electrolytes under severely confined conditions. Ionic current and…”
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Evaluation of the QTc prolongation potential of a monoclonal antibody, siltuximab, in patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, or low-volume multiple myeloma
Published in Cancer chemotherapy and pharmacology (2014)“…Purpose A phase 1 study evaluated the QTc prolongation potential of siltuximab, a chimeric, anti-interleukin-6 mAb, in patients with monoclonal gammopathy of…”
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Selective ion transport in functionalized carbon nanotubes
Published in Applied surface science (30-11-2017)“…[Display omitted] •MD simulations show ion transport within nanotubes is enhanced via functionalization.•Dramatic increases in current result from appropriate…”
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Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial
Published in The lancet oncology (01-09-2020)“…Venetoclax plus obinutuzumab has been established as a fixed-duration treatment regimen for patients with chronic lymphocytic leukaemia. We compared the…”
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Immunogenicity and safety of the adjuvanted recombinant zoster vaccine in adults with haematological malignancies: a phase 3, randomised, clinical trial and post-hoc efficacy analysis
Published in The Lancet infectious diseases (01-09-2019)“…The adjuvanted recombinant zoster vaccine (Shingrix) can prevent herpes zoster in older adults and autologous haemopoietic stem cell transplant recipients. We…”
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Selective ion transport in functionalized carbon nanotubes
Published in Applied surface science (01-11-2017)“…Not provided…”
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Non-Intensive Continuous Treatment with a Tyrosine Kinase Inhibitor (TKI) Followed By Allo-HSCT Is an Effective Therapeutic Strategy for Adult Ph-Positive Acute Lymphoblastic Leukemia: Outcomes of the Russian Prospective Multicenter RALL Study
Published in Blood (23-11-2021)“…Introduction. As Ph-positive (Ph+) ALL in adults remains less favorable in prognosis than other ALL, and by expert opinion needs non-intensive chemotherapy…”
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A phase 2, randomized, double‐blind, placebo‐controlled study of siltuximab (anti‐IL‐6 mAb) and bortezomib versus bortezomib alone in patients with relapsed or refractory multiple myeloma
Published in American journal of hematology (01-01-2015)“…We compared the safety and efficacy of siltuximab (S), an anti‐interleukin‐6 chimeric monoclonal antibody, plus bortezomib (B) with placebo (plc) + B in…”
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Lisaftoclax (APG-2575) Safety and Activity As Monotherapy or Combined with Acalabrutinib or Rituximab in Patients (pts) with Treatment-Naïve, Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (R/R CLL/SLL): Initial Data from a Phase 2 Global Study
Published in Blood (15-11-2022)Get full text
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Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane
Published in Science advances (03-06-2022)“…The increasing occurrence of antibiotic-resistant bacteria and the dwindling antibiotic research and development pipeline have created a pressing global health…”
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Trial in Progress: Phase 1b Study of Lisaftoclax (APG-2575) As a Single Agent or Combined with Other Therapeutic Agents in Patients with Relapsed and/or Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (R/R CLL/SLL)
Published in Blood (23-11-2021)“…Background: BCL-2 inhibition with venetoclax has proved to be highly effective treatment for patients with CLL. However, when administered to patients with CLL…”
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Outcomes in Patients with Hematologic Disease and COVID-19 in Russia: Interim Analysis of CHRONOS19 Registry
Published in Blood (05-11-2020)“…Background: Patients (pts) with hematologic disease are at increased risk of severe SARS-CoV-2 infection. Recent observations reported poor outcomes of…”
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Implementation experiences and insights from the scale‐up of an HIV assisted partner notification intervention in Central Asia
Published in Journal of the International AIDS Society (01-07-2019)“…Introduction WHO recommends assisted partner notification (APN) for people living with HIV (PLHIV). These services have not been widely scaled in Central Asia…”
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Social network methods for HIV case‐finding among people who inject drugs in Tajikistan
Published in Journal of the International AIDS Society (01-07-2018)“…Introduction HIV testing programmes have struggled to reach the most marginalized populations at risk for HIV. Social network methods such as respondent‐driven…”
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Clinical Outcomes in Patients With COVID-19 and Hematologic Disease
Published in Clinical lymphoma, myeloma and leukemia (01-08-2023)“…•Patients with hematologic disease and COVID-19 have high all-cause mortality at short-term follow-up, predominantly due to COVID-19 complications.•Patients…”
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Guiding optical modes in chains of dielectric particles
Published in Optics express (10-12-2007)“…We have investigated low frequency guiding polariton modes in finite linear chains of closely packed dielectric spherical particles of different optical…”
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MM-128: Carfilzomib, Dexamethasone, and Daratumumab (KdD) Versus Carfilzomib and Dexamethasone (Kd) in Relapsed or Refractory Multiple Myeloma (RRMM): Subgroup Analysis of the Phase 3 CANDOR Study by Number of Prior Lines of Therapy (pLOTs) and Prior Therapies
Published in Clinical lymphoma, myeloma and leukemia (01-09-2020)“…RRMM requires effective and tolerable treatments, particularly for those exposed or refractory to lenalidomide (LEN) or bortezomib (BOR).The CANDOR trial found…”
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