Search Results - "Samoszuk, Michael K"
-
1
Use of blood biomarkers to screen for obstructive sleep apnea
Published in Nature and science of sleep (01-01-2018)“…Obstructive sleep apnea (OSA) is a highly prevalent disorder associated with increased risk for cardiovascular disease, diabetes, and other chronic conditions…”
Get full text
Journal Article -
2
Eosinophils Are a Major Source of Nitric Oxide-Derived Oxidants in Severe Asthma: Characterization of Pathways Available to Eosinophils for Generating Reactive Nitrogen Species
Published in The Journal of immunology (1950) (01-05-2001)“…Eosinophil recruitment and enhanced production of NO are characteristic features of asthma. However, neither the ability of eosinophils to generate NO-derived…”
Get full text
Journal Article -
3
Improved Immunohistochemical Method for Detecting Hypoxia Gradients in Mouse Tissues and Tumors
Published in The journal of histochemistry and cytochemistry (01-06-2004)“…We describe an improved immunohistochemical procedure for detecting regions of hypoxia in normal organs and tumors in mice. The method employs a primary…”
Get full text
Journal Article -
4
Blood biomarkers of endocrine, immune, inflammatory, and metabolic systems in obstructive sleep apnea
Published in Clinical biochemistry (01-08-2016)“…Obstructive sleep apnea (OSA) is a common disorder, affecting over 100 million adults. Untreated OSA leads to serious health consequences and perturbations in…”
Get full text
Journal Article -
5
Selective Thrombosis of Tumor Blood Vessels in Mammary Adenocarcinoma Implants in Rats
Published in The American journal of pathology (01-07-2001)“…Adenocarcinomas in rats and humans frequently contain perivascular, degranulating mast cells that release heparin. Protamine is a low-molecular weight,…”
Get full text
Journal Article -
6
Eosinophils generate brominating oxidants in allergen-induced asthma
Published in The Journal of clinical investigation (15-05-2000)“…Eosinophils promote tissue injury and contribute to the pathogenesis of allergen-triggered diseases like asthma, but the chemical basis of damage to eosinophil…”
Get full text
Journal Article -
7
Assessment of protamine-induced thrombosis of tumor vessels for cancer therapy using dynamic contrast-enhanced MRI
Published in NMR in biomedicine (01-04-2002)“…Since the role of angiogenesis in cancer development has been recognized, the study of anti‐angiogenic or anti‐vascular therapeutic agents has become…”
Get full text
Journal Article -
8
Occult deposition of eosinophil peroxidase in a subset of human breast carcinomas
Published in The American journal of pathology (01-03-1996)“…Degranulation of eosinophils has been observed in a variety of human tumors and in other diseases but has not been previously described in breast cancer. To…”
Get full text
Journal Article -
9
Eradication of interleukin 5-transfected J558L plasmacytomas in mice by hydrogen peroxide-generating stealth liposomes
Published in Cancer research (Chicago, Ill.) (1996)“…Certain human tumors are extensively infiltrated by eosinophils and contain extracellular deposits of eosinophil peroxidase, which uses hydrogen peroxide as a…”
Get full text
Journal Article -
10
Effects of sonicated eosinophils on the in vitro sensitivity of human lymphoma cells to glucose oxidase
Published in Cancer research (Chicago, Ill.) (15-05-1994)“…We report here that cultured human lymphoma cells in the absence of sonicated eosinophils are sensitive to killing by glucose oxidase…”
Get full text
Journal Article -
11
-
12
-
13
-
14
-
15
-
16
Pharmacokinetic changes induced by vasomodulators in kidneys, livers, muscles, and implanted tumors in rats as measured by dynamic Gd-DTPA-enhanced MRI
Published in Magnetic resonance in medicine (01-12-1996)“…The effects of three physiologically different vasomodulators, angiotensin II (a vasoconstrictor), hydralazine (a vasodilator), and histamine (a permeability…”
Get more information
Journal Article -
17
An immunofluorescent assay for acute promyelocytic leukemia cells
Published in American journal of clinical pathology (01-02-1998)“…Sequential treatment with all-trans retinoic acid followed by chemotherapy significantly improves the long-term survival of patients who have acute…”
Get full text
Journal Article -
18
Radioimmunodetection of Hodgkin's Disease and Non-Hodgkin's Lymphomas with Monoclonal Antibody to Eosinophil Peroxidase
Published in The Journal of nuclear medicine (1978) (01-08-1993)“…The purpose of this study was to determine if a radiolabeled murine monoclonal antibody (EOS) directed against eosinophil peroxidase would localize…”
Get full text
Journal Article -
19
In-vitro sensitivity of Hodgkin's disease to hydrogen peroxide toxicity. Correlation with peroxidase activity
Published in Cancer (01-06-1989)“…Hodgkin's disease of nodular sclerosis and mixed cellularity subtypes contains numerous eosinophils and substantial amounts of extracellular eosinophil…”
Get more information
Journal Article -
20
Occult infections with M. intracellulare in bone-marrow biopsy specimens from patients with AIDS
Published in The New England journal of medicine (16-06-1983)Get more information
Journal Article