Search Results - "Samorì, Bruno"

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    Conformational equilibria in monomeric alpha-synuclein at the single-molecule level by Sandal, Massimo, Valle, Francesco, Tessari, Isabella, Mammi, Stefano, Bergantino, Elisabetta, Musiani, Francesco, Brucale, Marco, Bubacco, Luigi, Samorì, Bruno

    Published in PLoS biology (01-01-2008)
    “…Human alpha-Synuclein (alphaSyn) is a natively unfolded protein whose aggregation into amyloid fibrils is involved in the pathology of Parkinson disease. A…”
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    Journal Article
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    Evidence of Orientation-Dependent Early States of Prion Protein Misfolded Structures from Single Molecule Force Spectroscopy by Raspadori, Andrea, Vignali, Valentina, Murello, Anna, Giachin, Gabriele, Samorì, Bruno, Tanaka, Motomasa, Bustamante, Carlos, Zuccheri, Giampaolo, Legname, Giuseppe

    Published in Biology (Basel, Switzerland) (16-09-2022)
    “…Prion diseases are neurodegenerative disorders characterized by the presence of oligomers and amyloid fibrils. These are the result of protein aggregation…”
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    Journal Article
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    Probing Italy: A Scanning Probe Microscopy Storyline by Dinelli, Franco, Brucale, Marco, Valle, Francesco, Ascoli, Cesare, Samorì, Bruno, Sartore, Marco, Adami, Manuela, Galletti, Riccardo, Prato, Stefano, Troian, Barbara, Albonetti, Cristiano

    Published in Micro (01-06-2023)
    “…Starting from the late 1980’s, scanning probe microscopy has progressively diffused in Italy until today. In this paper, we provide a brief account of the main…”
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    Journal Article
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    Observing the osmophobic effect in action at the single molecule level by Aioanei, Daniel, Tessari, Isabella, Bubacco, Luigi, Samorì, Bruno, Brucale, Marco

    “…Protecting osmolytes are widespread small organic molecules able to stabilize the folded state of most proteins against various denaturing stresses in vivo…”
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    DNA Codes for Nanoscience by Samorì, Bruno, Zuccheri, Giampaolo

    Published in Angewandte Chemie International Edition (11-02-2005)
    “…The nanometer scale is a special place where all sciences meet and develop a particularly strong interdisciplinarity. While biology is a source of inspiration…”
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    Mastering the complexity of DNA nanostructures by Brucale, Marco, Zuccheri, Giampaolo, Samorì, Bruno

    Published in Trends in biotechnology (Regular ed.) (01-05-2006)
    “…The self-assembly of oligodeoxynucleotides is a versatile and powerful tool for the construction of objects in the nanoscale. The strictly information-driven…”
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    How Strong Is the Coordination Bond between a Histidine Tag and Ni - Nitrilotriacetate? An Experiment of Mechanochemistry on Single Molecules by Conti, Matteo, Falini, Giuseppe, Samorì, Bruno

    Published in Angewandte Chemie International Edition (03-01-2000)
    “…Isolation of a His‐tagged protein by means of a Ni – nitrilotriacetate‐functionalized chromatographic matrix or biosensor was simulated in a single‐molecule…”
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    Mapping the Intrinsic Curvature and Flexibility along the DNA Chain by Zuccheri, Giampaolo, Scipioni, Anita, Cavaliere, Valeria, Gargiulo, Giuseppe, De Santis, Pasquale, Samori, Bruno

    “…The energy of DNA deformation plays a crucial and active role in its packaging and its function in the cell. Considerable effort has gone into developing…”
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    Journal Article
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    The reaction of alpha-synuclein with tyrosinase: possible implications for Parkinson disease by Tessari, Isabella, Bisaglia, Marco, Valle, Francesco, Samorì, Bruno, Bergantino, Elisabetta, Mammi, Stefano, Bubacco, Luigi

    Published in The Journal of biological chemistry (13-06-2008)
    “…Oxidative stress appears to be directly involved in the pathogenesis of Parkinson disease. Several different pathways have been identified for the production…”
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    Journal Article
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    Chip cleaning and regeneration for electrochemical sensor arrays by Bhalla, Vijayender, Carrara, Sandro, Stagni, Claudio, Samorì, Bruno

    Published in Thin solid films (02-04-2010)
    “…Sensing systems based on electrochemical detection have generated great interest because electronic readout may replace conventional optical readout in…”
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    Journal Article
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    Recognition of the DNA Sequence by an Inorganic Crystal Surface by Sampaolese, Beatrice, Bergia, Anna, Scipioni, Anita, Zuccheri, Giampaolo, Savino, Maria, Samorì, Bruno, De Santis, Pasquale

    “…The sequence-dependent curvature is generally recognized as an important and biologically relevant property of DNA because it is involved in the formation and…”
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    Screen-printed electrodes based on carbon nanotubes and cytochrome P450scc for highly sensitive cholesterol biosensors by Carrara, Sandro, Shumyantseva, Victoria V., Archakov, Alexander I., Samorì, Bruno

    Published in Biosensors & bioelectronics (15-09-2008)
    “…This paper is concerned with an investigation of electron transfer between cytochrome P450scc (CYP11A1) immobilized on nanostructured rhodium–graphite…”
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    Pathogenic Mutations Shift the Equilibria of α-Synuclein Single Molecules towards Structured Conformers by Brucale, Marco, Sandal, Massimo, Di Maio, Selena, Rampioni, Aldo, Tessari, Isabella, Tosatto, Laura, Bisaglia, Marco, Bubacco, Luigi, Samorì, Bruno

    “…α-synuclein (α-Syn) is an abundant brain protein whose mutations have been linked to early-onset Parkinson's disease (PD). We recently demonstrated, by means…”
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    Journal Article
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    CMOS DNA Sensor Array With Integrated A/D Conversion Based on Label-Free Capacitance Measurement by Stagni, C., Guiducci, C., Benini, L., Ricco, B., Carrara, S., Samori, B., Paulus, C., Schienle, M., Augustyniak, M., Thewes, R.

    Published in IEEE journal of solid-state circuits (01-12-2006)
    “…This paper presents a fully electronic label-free DNA chip in 0.5-mum CMOS technology, with 5-V supply voltage, suitable for low-cost highly integrated…”
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    Journal Article Conference Proceeding
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    Worm-Like Ising Model for Protein Mechanical Unfolding under the Effect of Osmolytes by Aioanei, Daniel, Brucale, Marco, Tessari, Isabella, Bubacco, Luigi, Samorì, Bruno

    Published in Biophysical journal (18-01-2012)
    “…We show via single-molecule mechanical unfolding experiments that the osmolyte glycerol stabilizes the native state of the human cardiac I27 titin module…”
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    Open source platform for the execution and analysis of mechanical refolding experiments by ALOANEL, Daniel, BRUCALE, Marco, SAMORI, Bruno

    Published in Bioinformatics (01-02-2011)
    “…Single-molecule force spectroscopy has facilitated the experimental investigation of biomolecular force-coupled kinetics, from which the kinetics at zero force…”
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