Search Results - "Sammani, S"

Differential and opposing effects of imatinib on LPS- and ventilator-induced lung injury by Letsiou, E, Rizzo, A N, Sammani, S, Naureckas, P, Jacobson, J R, Garcia, J G N, Dudek, S M

“…Endothelial dysfunction underlies the pathophysiology of vascular disorders such as acute lung injury (ALI) syndromes. Recent work has identified the Abl…”
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Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro by Camp, S M, Bittman, R, Chiang, E T, Moreno-Vinasco, L, Mirzapoiazova, T, Sammani, S, Lu, X, Sun, C, Harbeck, M, Roe, M, Natarajan, V, Garcia, J G N, Dudek, S M

“…Novel therapies are needed to address the vascular endothelial cell (EC) barrier disruption that occurs in inflammatory diseases such as acute lung injury…”
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Suppression of endotoxin-induced inflammation by taxol by Mirzapoiazova, T, Kolosova, I. A, Moreno, L, Sammani, S, Garcia, J. G. N, Verin, A. D

“…The pathogenesis of acute lung injury includes transendothelial diapedesis of leukocytes into lung tissues and disruption of endothelial/epithelial barriers…”
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Amifostine reduces lung vascular permeability via suppression of inflammatory signalling by Fu, P, Birukova, A. A, Xing, J, Sammani, S, Murley, J. S, Garcia, J. G. N, Grdina, D. J, Birukov, K. G

“…Despite an encouraging outcome of antioxidant therapy in animal models of acute lung injury, effective antioxidant agents for clinical application remain to be…”
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242: Pre-B-Cell Colony Enhancing Factor (PBEF) Is a Novel target in Hypoxia-Induced Murine Pulmonary Hypertension by Machado, R.F, Moreno-Vinasco, L, Zaidi, R, Sammani, S, Garcia, J.G.N

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37 A REEVALUATION OF EVANS BLUE DYE AS A MARKER OF ALBUMIN CLEARANCE IN MOUSE MODELS OF ACUTE LUNG INJURY by Sammani, S., Moitra, J., Garcia, J. G.N.

“…BackgroundQuantifying the amount of albumin conjugated to Evans Blue dye (Alb-EB) fluxing across organ barriers is a popular technique to measure intactness of…”
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52 A NOVEL MYOSIN LIGHT CHAIN KINASE INHIBITOR, PIK, PROTECTS FROM LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY by Mirzapoiazova, T., Sammani, S., Moreno, L., Dudek, S. M., Turner, J. R., Garcia, J. G.

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are major causes of acute respiratory failure that are associated with high morbidity…”
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88 EFFECT OF THE S1P1 GENE KO ON LIPOPOLYSACCHARIDE-INDUCED MURINE ACUTE LUNG INJURY by Sammani, S., Mirzapoiazova, T., Moreno, L., Proia, R., Evenoski, C., Moitra, J., Natarajan, V., Singleton, P., Garcia, J. G.

“…Acute lung injury ALI/ARDS, a significant cause of morbidity and mortality, is characterized by a diffuse inflammatory parenchymal process with pulmonary EC…”
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89 LIPID RAFT REGULATION OF HEPATOCYTE GROWTH FACTOR/C-MET-MEDIATED VASCULAR INTEGRITY: ROLE OF CD44, TIAM1/RAC1, DYNAMIN 2, AND CORTACTIN by Singleton, P. A., Salgia, R., Moreno-Vinasco, L., Moitra, J., Sammani, S., Mirzapoiazova, T., Dudek, S. M., Garcia, J.

“…Endothelial cell (EC) barrier dysfunction results in increased vascular permeability, a feature of inflammation, tumor angiogenesis, atherosclerosis, and acute…”
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3 SUPPRESSION OF LIPOPOLYSACCHARIDE-INDUCED ACUTE LUNG INJURY BY TAXOL by Mirzapoiazova, T., Moreno, L., Sammani, S., Kolosova, I., Garcia, J. G., Verin, A. D.

“…Our prior study demonstrated that similar to actin cytoskeleton, mictotubule (MT) network is a key participant in the regulation of endothelial (EC)…”
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B28 BARRIER DYNAMICS IN THE PULMONARY CIRCULATION: Pf-573,228, An Inhibitor Of Focal Adhesion Kinase, Uniquely Mediates Pulmonary Endothelial Barrier Protection by Lederer, P, Sammani, S, Jacobson, J R

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23 IDENTIFICATION OF ORGAN-SHARED AND STRAIN-INDEPENDENT CANDIDATE GENES DURING COMBINED VENTILATOR-ASSOCIATED LUNG AND KIDNEY INJURY by Grigoryev, D. N., Sammani, S., Ma, S.-F., Ye, S. Q., Barnes, K. C., Rabb, H., Garcia, J. G.N.

“…Combined ventilator-induced lung injury (VILI) and acute renal failure (ARF) have 80% mortality in the ICU. We hypothesized that analysis of global genetic…”
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27 PROTECTIVE EFFECT OF PURINERGIC AGONIST ATPgS AGAINST ACUTE LUNG INJURY by Kolosova, I. A., Mirzapoiazova, T., Moreno, L., Sammani, S., Garcia, J. G., Verin, A. D.

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are major causes of acute respiratory failure that are associated with high morbidity…”
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76 ATTENUATION OF A RODENT MODEL OF PULMONARY HYPERTENSION: A NOVEL ROLE FOR SORAFENIB, A MULTIKINASE INHIBITOR by Desai, A. A., Moreno, L., Gomberg-Maitland, M. M., Maitland, M., Collins, K., Sammani, S., Ma, S., Husain, A. N., Liu, Y., Sam, L., Lang, R. M., Ratain, M. J., Lussier, Y. A., Garcia, J.

“…Drawing from new drug discovery studies is the observation that severe pulmonary hypertension (PH) and cancer pathophysiology share common signal transduction…”
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Parkin regulates LPS-induced pro-inflammatory responses in acute lung injury by Letsiou, E, Sammani, S, Wang, H, Belvitch, P, Dudek, S.M

“…Abstract The Acute Respiratory Distress Syndrome (ARDS) is a serious condition resulting from direct or indirect lung injury that is associated with high…”
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C105 RESPIRATORY FAILURE: MECHANISTIC INSIGHTS FROM LUNG INJURY MODELS: Parkin Mediates Endothelial Inflammatory Responses In Acute Lung Injury by Letsiou, E, Sammani, S, Wang, H, Belvitch, P G, Dudek, S M

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C28 THE TIES THAT BIND: BASIC STUDIES IN ALI AND BARRIER FUNCTION: Trefoil Factor 2 Is A Novel Regulator Of Vascular Barrier Dysfunction In Lung Injury by Wu, X, Sammani, S, Infusino, G A, Dudek, S M, Garcia, J G N, Wang, T

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ID: 109: PARKIN MEDIATES ENDOTHELIAL PRO-INFLAMMATORY RESPONSES IN ACUTE LUNG INJURY by Letsiou, E, Wang, H, Belvitch, P, Dudek, S, Sammani, S

“…IntroductionAcute lung injury (ALI) and its more severe form, the Acute Respiratory Distress Syndrome (ARDS), are serious conditions resulting from direct or…”
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Parkin Mediates Endothelial Pro-Inflammatory Responses in Acute Lung Injury by Letsiou, E, Wang, H, Belvitch, P, Dudek, S, Sammani, S

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A57 LUNG INJURY, REPAIR, AND FIBROSIS: THE PLOT THICKENS FOR THREE'S COMPANY: Mice With Sickle Cell Disease Are Protected From Ventilator-Induced Lung Injury But Not LPS-Induced Lung Injury by Sysol, J R, Sammani, S, Letsiou, E, Singla, S, Dudek, S M, Machado, R F

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