Search Results - "Samiulla, Dodheri Syed"

Exploration of the Plausible Mechanism of Ethambutol Induced Ocular Toxicity by Using Proteomics Informed Physiologically Based Pharmacokinetic (PBPK) Modeling by Balhara, Ankit, Ladumor, Mayur K., Nankar, Rakesh P., Syed, Samiulla Dodheri, Giri, Sanjeev, Prasad, Bhagwat, Singh, Saranjit

“…Purpose Ethambutol (EMB) is a first-line anti-tubercular drug that is known to cause optic neuropathy. The exact mechanism of its eye toxicity is unknown;…”
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Bioavailability of Eurycomanone in Its Pure Form and in a Standardised Eurycoma longifolia Water Extract by Ahmad, Norzahirah, Samiulla, Dodheri Syed, Teh, Bee Ping, Zainol, Murizal, Zolkifli, Nor Azlina, Muhammad, Amirrudin, Matom, Emylyn, Zulkapli, Azlina, Abdullah, Noor Rain, Ismail, Zakiah, Syed Mohamed, Ami Fazlin

“…is one of the commonly consumed herbal preparations and its major chemical compound, eurycomanone, has been described to have antimalarial, antipyretic,…”
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Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis by Balhara, Ankit, Kumar, Avinash, Kumar, Suryakant, Samiulla, Dodheri Syed, Giri, Sanjeev, Singh, Saranjit

“…•First report regarding investigation of inhibition potential of isoniazid and its four major metabolites towards CYP2E1 enzyme.•Fraction unbound in microsomal…”
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Discovery of indole tetrafluorophenoxymethylketone-based potent novel small molecule inhibitors of caspase-3 by Samiulla, Dodheri Syed, Naidu, Andra, Rao, Gummadi Venkateshwar, Ramachandra, Murali

“…Background Caspase-3 inhibition has been demonstrated to be therapeutically effective in moderating excessive programmed cell death. Interest in caspase-3 as a…”
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