Search Results - "Samir, Saheb"
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Preemptive rituximab prevents long-term relapses in immune-mediated thrombotic thrombocytopenic purpura
Published in Blood (15-11-2018)“…Preemptive rituximab infusions prevent relapses in immune thrombotic thrombocytopenic purpura (iTTP) by maintaining normal ADAMTS13 activity. However, the…”
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Late antibody-mediated rejection after heart transplantation: Mortality, graft function, and fulminant cardiac allograft vasculopathy
Published in The Journal of heart and lung transplantation (01-08-2015)“…Background Late antibody-mediated rejection (AMR) after heart transplantation is suspected to be associated with a poor short-term prognosis. Methods A…”
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A 10 Patient Case Report on the Impact of Plasmapheresis Upon Neutralizing Factors Against Adeno-associated Virus (AAV) Types 1, 2, 6, and 8
Published in Molecular therapy (01-11-2011)“…Adeno-associated viruses (AAV) are small, nonenveloped single-stranded DNA viruses which require helper viruses to facilitate efficient replication. These…”
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Predictive features of severe acquired ADAMTS13 deficiency in idiopathic thrombotic microangiopathies: the French TMA reference center experience
Published in PloS one (23-04-2010)“…Severe ADAMTS13 deficiency occurs in 13% to 75% of thrombotic microangiopathies (TMA). In this context, the early identification of a severe,…”
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Long-term efficacy of lipoprotein apheresis and lomitapide in the treatment of homozygous familial hypercholesterolemia (HoFH): a cross-national retrospective survey
Published in Orphanet journal of rare diseases (08-09-2021)“…Abstract Background Homozygous familial hypercholesterolemia (HoFH) is a rare life-threatening condition that represents a therapeutic challenge. The vast…”
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LDL apheresis as an alternate method for plasma LPS purification in healthy volunteers and dyslipidemic and septic patients
Published in Journal of lipid research (01-12-2020)“…Lipopolysaccharide (LPS) is a key player for innate immunity activation. It is therefore a prime target for sepsis treatment, as antibiotics are not sufficient…”
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Thrombotic Thrombocytopenic Purpura in Black People: Impact of Ethnicity on Survival and Genetic Risk Factors
Published in PloS one (06-07-2016)“…Black people are at increased risk of thrombotic thrombocytopenic purpura (TTP). Whether clinical presentation of TTP in Black patients has specific features…”
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Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infection
Published in Stem cell research & therapy (29-07-2019)“…Familial hypercholesterolemia type IIA (FH) is due to mutations in the low-density lipoprotein receptor (LDLR) resulting in elevated levels of low-density…”
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Impact of Sex in the Efficacy of Perioperative Desensitization Procedures in Heart Transplantation: A Retrospective Cohort Study
Published in Frontiers in immunology (07-07-2021)“…Background Sensitized patients, i.e. recipients with preformed donor-specific HLA antibodies (pfDSA), are at high-risk of developing antibody-mediated…”
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Small, dense high-density lipoprotein 3 particles exhibit defective antioxidative and anti-inflammatory function in familial hypercholesterolemia: Partial correction by low-density lipoprotein apheresis
Published in Journal of clinical lipidology (01-01-2016)“…Background Familial hypercholesterolemia (FH) features elevated oxidative stress and accelerated atherosclerosis driven by elevated levels of atherogenic…”
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Tremor Associated with Chronic Inflammatory Demyelinating Polyneuropathy and Anti-Neurofascin-155 Antibodies
Published in Tremor and other hyperkinetic movements (New York, N.Y.) (04-12-2018)“…BackgroundTremor is an underrecognized feature in certain neuropathy subtypes. Phenomenology shownWe show a patient with a disabling neuropathic tremor and…”
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LDL-apheresis depletes apoE-HDL and pre-β1-HDL in familial hypercholesterolemia: relevance to atheroprotection
Published in Journal of lipid research (01-12-2011)“…Subnormal HDL-cholesterol (HDL-C) and apolipoprotein (apo)AI levels are characteristic of familial hypercholesterolemia (FH), reflecting perturbed…”
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Urgent therapeutic plasma exchange
Published in Transfusion and apheresis science (01-12-2020)“…Therapeutic plasma exchange (TPE) is a well-established therapeutic procedure commonly used in many disorders of autoimmune etiology. The beneficial effects of…”
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Long-term efficacy of evinacumab and improved cardiovascular outcome in patients with homozygous familial hypercholesterolaemia
Published in Atherosclerosis (01-08-2024)Get full text
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Evinacumab and Cardiovascular Outcome in Patients With Homozygous Familial Hypercholesterolemia
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2024)“…Patients with homozygous familial hypercholesterolemia (HoFH) remain at very high cardiovascular risk despite the best standard of care lipid-lowering…”
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Homozygous familial hypercholesterolaemia: Low density lipoprotein-cholesterol (LDL-C) monitoring for 15 years
Published in Atherosclerosis (01-08-2024)Get full text
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Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis
Published in Cancer discovery (04-05-2023)“…Immune-checkpoint-inhibitor (ICI)-associated myotoxicity involves the heart (myocarditis) and skeletal muscles (myositis), which frequently occur concurrently…”
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Plasma exchange response in 34 patients with severe optic neuritis
Published in Journal of neurology (01-05-2016)“…Optic neuritis could lead to severe visual impairment despite corticosteroids. Our aim was to evaluate the rate of visual improvement in patients treated with…”
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Impact of LDL apheresis on aortic root atheroma in children with homozygous familial hypercholesterolemia
Published in Atherosclerosis (01-03-2015)“…Abstract Background Homozygous familial hypercholesterolemia (HFH) is a rare genetic disease leading to early onset atherosclerosis, due to high concentrations…”
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Evinacumab in homozygous familial hypercholesterolaemia: long-term safety and efficacy
Published in European heart journal (12-07-2024)“…Abstract Background and Aims Homozygous familial hypercholesterolaemia (HoFH) is a rare genetic disorder characterized by severely elevated LDL cholesterol…”
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