Search Results - "Samir, Eman M."

Synthesis and anti-proliferative activity of some new quinoline based 4,5-dihydropyrazoles and their thiazole hybrids as EGFR inhibitors by George, Riham F., Samir, Eman M., Abdelhamed, Mennatullah N., Abdel-Aziz, Hatem A., Abbas, Safinaz E-S.

“…The quinolinyl/pyrazolinyl thiazole hybrid 6b exhibited promising anti-proliferative activity against MCF-7 (breast), HeLa (cervical) and DLD1(colon) cancer…”
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Synthesis and docking studies of pyran, pyridine and thiophene derivatives and their antitumor evaluations against cancer, hepatocellular carcinoma and cervical carcinoma cell lines by Mohareb, Rafat M., Ibrahim, Rehab A., Samir, Eman M.

“…This work aimed to produce novel heterocyclic compounds such as chromene, thieno[3,2-f]chromene, chromeno[5,6-d]thiazole and quinoline derivatives. The newly…”
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Synthesis, and anti-proliferative, Pim-1 kinase inhibitors and molecular docking of thiophenes derived from estrone by Mohareb, Rafat M., Samir, Eman M., Halim, Peter A.

“…[Display omitted] •Heterocyclization reactions of estrone were studied.•Structures of the newly synthesized products were confirmed.•Cytotoxicity, toxicity,…”
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Synthesis and evaluation of novel 4H‐pyrazole and thiophene derivatives derived from chalcone as potential anti‐proliferative agents, Pim‐1 kinase inhibitors, and PAINS by Megally Abdo, Nadia Y., Samir, Eman M., Mohareb, Rafat M.

“…The chalcone derivatives 3a‐d reacted with either malononitrile or ethyl cyanoacetate in ethanol in the presence of catalytic amount of ammonium acetate in an…”
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Synthesis and anticancer activity of some pyrido[2,3- d ]pyrimidine derivatives as apoptosis inducers and cyclin-dependent kinase inhibitors by Abbas, Safinaz E-S, George, Riham F, Samir, Eman M, Aref, Mostafa Ma, Abdel-Aziz, Hatem A

“…Due to emergence of resistance to available anticancer agents, there is a need to search for new cytotoxic agents. Pyrido[2,3- ]pyrimidines ( - ) and their…”
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Novel synthesis of pyran-3-hydrazide derivatives and their uses to the synthesis hydrazide-hydrazone, pyrazole and thiazole derivatives with anticancer activities by Samir, Eman M, Mohareb, Rafat M

“…The multi-component reaction of ethyl acetoacetate with each of malononitrile (3) benzaldehyde (1) in ethanol containing triethylamine gave the ethyl…”
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Synthesis and in vitro antiproliferative activity of certain novel pyrazolo[3,4‐b]pyridines with potential p38α MAPK‐inhibitory activity by Farahat, Aya A., Samir, Eman M., Zaki, Mayssoune Y., Serya, Rabah A. T., Abdel‐Aziz, Hatem A.

“…Novel series of pyrazolo[3,4‐b]pyridines 9a–j and 14a–f were prepared via a one‐pot three‐component reaction. Compounds 9a–j were synthesized by the reaction…”
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Synthesis and cytotoxicity of novel thiophene, pyran and pyridine derivatives by W. Wardakhan, W., M. Samir, E., E. El-Arab, E.

“…The reaction of 2-amino-3-cyano-tetrahydrobenzothiophene 3 with ethyl acetoacetate gave the amide derivatives 5. The reactivity of 5 toward a variety of…”
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The Reaction of Cyclopentanone with Cyanomethylene Reagents: Novel Synthesis of Pyrazole, Thiophene, and Pyridazine Derivatives by Wardakhan, Wagnat W., Samir, Eman M.

“…The reaction of cyclopentanone with either malononitrile or ethyl cyanoacetate gave the corresponding condensated products. The latter underwent some…”
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Synthesis and evaluation of novel 4 H ‐pyrazole and thiophene derivatives derived from chalcone as potential anti‐proliferative agents, Pim‐1 kinase inhibitors, and PAINS by Megally Abdo, Nadia Y., Samir, Eman M., Mohareb, Rafat M.

“…Abstract The chalcone derivatives 3a‐d reacted with either malononitrile or ethyl cyanoacetate in ethanol in the presence of catalytic amount of ammonium…”
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Synthesis and in vitro antiproliferative activity of certain novel pyrazolopyridines with potential p38α MAPK‐inhibitory activity by Farahat, Aya A, Samir, Eman M, Zaki, Mayssoune Y, Serya, Rabah A T, Hatem A Abdel‐Aziz

“…Novel series of pyrazolo[3,4‐b]pyridines 9a–j and 14a–f were prepared via a one‐pot three‐component reaction. Compounds 9a–j were synthesized by the reaction…”
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The Reaction of Cyclopentanone with Cyanomethylene Reagents : Novel Synthesis of Pyrazole, Thiophene, and Pyridazine Derivatives by Wardakhan, Wagnat W., Samir, Eman M.

“…The reaction of cyclopentanone with either malononitrile or ethyl cyanoacetate gave the corresponding condensated products. The latter underwent some…”
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